Clinical trials · Riverside–San Bernardino, CA
Chronic Disease clinical trials in Riverside–San Bernardino
We’re tracking 56 recruiting chronic disease studies with a site in or near Riverside–San Bernardino — including Phase 1, Phase 2, Phase 2/Phase 3 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies near Riverside–San Bernardino
- NCT06585774RecruitingPhase 3
Axatilimab plus steroids for new chronic GVHD
This study tests a new drug called axatilimab combined with steroids as a first treatment for chronic graft-versus-host disease (GVHD) after a stem cell transplant. It aims to see if this combination helps control symptoms better than steroids alone.
Duarte, CaliforniaAges 12 years+ - NCT06859424RecruitingPhase 2
Testing a new GVHD prevention method after donor stem cell transplant
This trial tests a new way to prevent graft-versus-host disease (a common side effect of stem cell transplant) using a drug called cyclophosphamide after transplant. It is for adults with certain blood cancers who need a transplant from a partially matched unrelated donor.
Duarte, CaliforniaAges 18–66 - NCT05996627RecruitingPhase 2
Belumosudil for early treatment of chronic graft-versus-host disease
This trial tests a pill called belumosudil to see if it can help people with chronic graft-versus-host disease (a common complication after a stem cell transplant where donor cells attack your body). It is for patients who have symptoms but are not yet on strong immune-suppressing drugs.
Duarte, CaliforniaAges 18 years+ - NCT07025538RecruitingPhase 1
Preventing chronic graft-versus-host disease with ruxolitinib
This trial tests whether the drug ruxolitinib, given based on a blood test that predicts risk, can prevent chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It may help people who have a higher risk of developing this complication.
Duarte, CaliforniaAges 18 years+ - NCT04710576RecruitingPhase 2
Axatilimab for chronic graft-versus-host disease
This trial tests a new drug called axatilimab to help patients whose chronic graft-versus-host disease (a condition where transplanted immune cells attack the body) isn't responding well to standard treatments. Researchers want to find the right dose and see if it can improve symptoms and quality of life.
Duarte, CaliforniaAges 2 years+ - NCT07662135RecruitingPhase 3
A study of elecoglipron for type 2 diabetes with kidney problems
This trial tests a new medicine called elecoglipron to see if it helps control blood sugar in people with type 2 diabetes who also have reduced kidney function. You would continue taking your current SGLT2i medication (like dapagliflozin).
Victorville, CaliforniaAges 18 years+ - NCT07363694RecruitingPhase 2/Phase 3
Study of PF-07275315 for moderate to severe COPD
This trial tests a new medicine called PF-07275315 for people with moderate to severe COPD. It aims to see if it can help reduce flare-ups (sudden worsening of symptoms) when added to your usual treatment.
La Palma, CaliforniaAges 35–80 - NCT07190209RecruitingPhase 3
Testing lunsekimig for COPD with frequent flare-ups
This trial tests a new medicine called lunsekimig for people with COPD that still causes flare-ups despite standard treatment. It focuses on people with higher blood eosinophils (a type of white blood cell). If you smoke or used to smoke and have had at least 2 moderate or 1 severe flare-up in the past year, this study may be an option.
La Palma, CaliforniaAges 40–80 - NCT07304154RecruitingPhase 1
Study of KITE-363 for autoimmune nerve diseases
This trial tests a new treatment called KITE-363 for people with certain autoimmune nerve diseases, such as multiple sclerosis, myasthenia gravis, or chronic inflammatory demyelinating polyneuropathy, that have not responded well to standard therapies. The goal is to see if it is safe and effective.
Newport Beach, CaliforniaAges 18–75 - NCT07177339RecruitingPhase 3
Testing depemokimab for COPD with type 2 inflammation
This study tests an early treatment called depemokimab for people with moderate to severe COPD who have a type of inflammation linked to high eosinophils. It aims to reduce flare-ups and improve breathing.
Newport Beach, CaliforniaAges 40–75 - NCT07759245RecruitingPhase 2
Brenipatide for moderate-to-severe COPD
This trial tests a new medicine called Brenipatide to see if it can help people with moderate-to-severe COPD who still have symptoms despite using standard inhalers. The study will compare the effects of Brenipatide against a placebo to understand if it is safe and effective.
Newport Beach, CaliforniaAges 40–75 - NCT07793409RecruitingPhase 3
Long-term safety study of lunsekimig for COPD
This study is a long-term follow-up for people with COPD who have already completed an earlier lunsekimig study. It aims to check the safety and effectiveness of the treatment over a longer period.
Newport Beach, CaliforniaAges 40–80 - NCT06959095RecruitingPhase 3
Depemokimab for adults with COPD and type 2 inflammation
This trial tests a new biologic medicine called depemokimab, given as an injection, to see if it reduces flare-ups (exacerbations) in people with COPD who have a specific type of inflammation (high eosinophils). It may help if you have frequent flare-ups despite using your regular inhalers.
Newport Beach, CaliforniaAges 40–80 - NCT07753993RecruitingPhase 3
Study of elecoglipron for chronic kidney disease
This trial tests an investigational medicine called elecoglipron for people with chronic kidney disease. It aims to see if it can improve kidney health compared to a placebo (inactive pill) and may be an option for those already on standard blood pressure and kidney protective medications.
Huntington Beach, CaliforniaAges 18 years+ - NCT07714252Enrolling by invitation
Virtual palliative care team for veterans with heart or lung disease
This study tests a virtual team of nurses and social workers who provide palliative care to veterans with heart failure, COPD, or interstitial lung disease. The goal is to improve quality of life by offering extra support at home.
Long Beach, CaliforniaAges 18 years+ - NCT07190222RecruitingPhase 3
New medicine for COPD with frequent flare-ups
This study tests a new medicine called Lunsekimig for people with COPD that has frequent flare-ups and high eosinophil levels (a sign of inflammation). It aims to see if it can help control symptoms better than a placebo (a dummy treatment).
Long Beach, CaliforniaAges 40–80 - NCT05465044Recruiting
Twice-weekly dialysis for veterans starting kidney treatment
This study compares starting hemodialysis two times per week versus three times per week for veterans in their first year of dialysis. It aims to see if a less frequent schedule can be just as safe and effective for those who still make urine.
Long Beach, CaliforniaAges 18 years+ - NCT07391904Enrolling by invitation
Testing lab result communication for older adults
This study tests a tool designed to help older adults understand their lab results more easily. Researchers want to see if the tool improves patient understanding and engagement.
Los Angeles, CaliforniaAges 65 years+ - NCT05457283RecruitingPhase 3
Finerenone safety study for children with kidney disease
This trial studies how safely finerenone works over 18 months in children and young adults with chronic kidney disease who also take an ACE inhibitor or ARB. It aims to better understand long-term side effects when used together with standard kidney blood-pressure medicines.
Los Angeles, CaliforniaAges 1–18 - NCT03633708RecruitingPhase 3
Etelcalcetide for children with dialysis-related overactive parathyroid hormone
This trial studies etelcalcetide in children who have chronic kidney disease and too much parathyroid hormone while on hemodialysis. It aims to safely lower the hormone levels and help manage related bone/mineral problems.
Los Angeles, CaliforniaAges birth–18 years - NCT06476132RecruitingPhase 2
Belumosudil for lung transplant patients at risk of chronic rejection
This trial tests whether the drug Belumosudil can help prevent chronic lung rejection in people who recently had a lung transplant and showed signs of early rejection. It may improve long-term lung health.
Los Angeles, CaliforniaAges 12 years+ - NCT06376994RecruitingPhase 3
Clean air study for COPD
This study tests if using air cleaners at home improves lung health in people with COPD. If you qualify, you may get an air cleaner for your home and be followed for 12 months.
Los Angeles, CaliforniaAges 40 years+ - NCT06877169Recruiting
Staged heart and kidney transplant study
This study compares two ways of doing a combined heart and kidney transplant. It looks at doing the surgeries in separate stages instead of all at once, to see if that is safer or works better.
Los Angeles, CaliforniaAges 18 years+ - NCT06016257Recruiting
Virtual home exercise program for shoulder rehab
This study tests a virtual home exercise program (VirtuaCare) for people with shoulder problems who need physical therapy. It aims to see if doing exercises at home with virtual guidance works as well as standard care.
Los Angeles, CaliforniaAges 18 years+
Hear when a new Chronic Disease trial opens near Riverside–San Bernardino, CA
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Chronic Disease trials in other cities
Where these studies are running near Riverside–San Bernardino
Institutions with a site for the recruiting chronic disease studies listed above.
- City of Hope · 5 studies
- Cedars-Sinai Medical Center · 2 studies
- GSK Investigational Site · 2 studies
- NewportNativeMD, Inc. · 2 studies
- Research Site · 2 studies
- VA Long Beach Healthcare System, Long Beach, CA · 2 studies
- Alliance Clinical - West Hills
- Ark Clinical Research
What taking part in a chronic disease study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting chronic disease studies in California.
Common questions
- Are there chronic disease clinical trials near Riverside–San Bernardino?
- Yes. We're currently tracking 56 recruiting chronic disease studies with a site near Riverside–San Bernardino, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a chronic disease study near Riverside–San Bernardino?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Riverside–San Bernardino to take part?
- Not necessarily. These studies have a site near Riverside–San Bernardino, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New chronic disease studies open near Riverside–San Bernardino regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.