Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06718283Recruiting
A study of blood tests in young people with lupus
This study looks at blood test results in children and teenagers with lupus to see if they relate to how active the disease is or if it has caused long-term damage. It may help doctors better understand the disease.
SohagAges Up to 18 years - NCT07098351Recruiting
A trial for a new itchy skin medicine for people on peritoneal dialysis
This trial tests if a medication called nalfurafine hydrochloride (taken as a tablet that melts in your mouth) can help reduce moderate to severe itching in people receiving peritoneal dialysis for chronic kidney disease.
Guangzhou, GuangdongAges 18–85 - NCT04018729RecruitingPhase 2/Phase 3
Cell treatment through a breathing tube for severe emphysema
This trial tests a cell-based treatment placed into the lung using an airway valve, to help people with severe emphysema breathe easier. You may be eligible if your emphysema is uneven in the lungs and testing suggests your “collateral ventilation” is low, meaning the treatment area may benefit more from blocking airflow.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06419036Enrolling by invitation
Using medical devices to monitor COPD at home
This study tests whether wearable medical devices can help monitor your COPD symptoms at home. You will use a smartphone app and a small chest patch to track your breathing, which may help you and your doctor better manage your condition.
GlasgowAges 18 years+ - NCT06531798RecruitingPhase 4
Safety study of Breztri aerosphere in Indian COPD patients
This study tests a medication called Breztri aerosphere (a triple-combination inhaler) to see how safe and well-tolerated it is in Indian patients with COPD who have had recent flare-ups. It may help people who need better control of their breathing symptoms.
Dalgate, DrugjanAges 18 years+ - NCT07192016RecruitingPhase 4
MRI study of triple inhaler for COPD with breathlessness
This study uses a special MRI scan to see how well a single triple inhaler works for people with COPD who have moderate to severe shortness of breath or feel their health is not good. It compares two groups: those with a low risk of flare-ups and those with a high risk, to find out if the treatment helps both groups.
London, OntarioAges 50–85 - NCT07728695RecruitingPhase 1/Phase 2
Cannabis product for gynecologic pain study
This trial tests a new cannabis-based product to see if it helps with gynecologic pain (like endometriosis). It looks at how the product works and whether it is safe and effective.
Belmont, MassachusettsAges 21 years+ - NCT07413172RecruitingPhase 2
Testing serum tears for severe dry eye
This study tests whether eye drops made from your own blood serum (with a natural lubricant) can relieve moderate-to-severe dry eye better than a standard salt solution. If you have dry eye from certain immune conditions or nerve damage, this may help find a more effective treatment.
Miami, FloridaAges 18 years+ - NCT06958666Recruiting
Comparing two breathing exercises for COPD symptoms
This study compares two breathing exercise methods (DITM vs IMT) for people with COPD to see which helps improve symptoms and quality of life better. It's for people who are already using a specific type of inhaler.
Hangzhou, ZhejiangAges 40 years+ - NCT06862206Recruiting
Benralizumab study for severe asthma in China
This study looks at people in China with severe eosinophilic asthma who are starting a new medicine called benralizumab. It will collect information about their symptoms and quality of life to understand who benefits most.
AnhuiAges Any age - NCT06334575RecruitingPhase 4
COPD treatment study based on eosinophil levels
This trial tests if inhaled corticosteroids (ICS) work better for COPD patients with different eosinophil levels. You must already be taking two long-acting bronchodilators and have stopped smoking for at least 6 months.
MarburgAges 40 years+ - NCT07707245Recruiting
Finding biomarkers in lung disease and lung cancer
This trial studies blood and tissue samples from people with COPD, IPF, or lung cancer to find markers that can help diagnose and predict these conditions. It aims to discover why some lung diseases progress to cancer.
Milan, MilanAges 18 years+ - NCT07707271Recruiting
Continuous vs. interval exercise for COPD
This trial compares two types of exercise training—steady moderate exercise versus short bursts of higher intensity—to see which is more helpful for people with COPD. It aims to find a better way to improve your breathing and fitness.
Thessaloniki, ExohiAges Any age - NCT03033251Recruiting
Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups
This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.
Toronto, OntarioAges 40 years+ - NCT03331302RecruitingPhase 1/Phase 2
Tested lung imaging scans in stable COPD patients
This study compares two ways of seeing how well your lungs work: a special MRI scan and another scan that uses a different gas. It may help researchers find which imaging test best reflects lung function in people with COPD.
Charlottesville, VirginiaAges 18 years+ - NCT03799354Recruiting
Strength training study for people with COPD
This trial tests whether a maximal strength training program can help people with COPD who are stable. It is looking at people with moderate-to-severe airflow limitation and excludes several other lung and health problems.
Lumezzane, BresciaAges 50–80 - NCT04179981Recruiting
CPAP treatment effects in older COPD and sleep apnea patients
This study looks at whether using positive airway pressure (often called CPAP) improves health outcomes in older adults who have both COPD and obstructive sleep apnea. It may help find ways to reduce symptoms and complications from “overlap” breathing problems.
Detroit, MichiganAges 60 years+ - NCT04200079Recruiting
Long-term follow-up study for people with COPD
This study follows people with COPD over time to better understand their lung health and how it changes. It may help researchers and doctors learn what factors affect breathing and long-term outcomes.
Kingston, OntarioAges 40–85 - NCT04220463Recruiting
Hypnosis during noninvasive breathing support for ICU lung illness
This trial tests whether hypnosis can help people in the ICU who need noninvasive breathing support (breathing help without a tube) for breathing flare-ups related to COPD and/or obesity. It aims to make this treatment easier and safer while you are awake.
Rennes, Brittany RegionAges 18 years+ - NCT04664491Recruiting
Program to reduce COPD flare-ups with standardized care
This study tests whether a structured care program for COPD can lower how often your symptoms flare up. It may help by improving everyday management and preventing future worsening.
Beijing, Beijing MunicipalityAges 40 years+ - NCT04722835Recruiting
Study lung immune cells in people at risk for COPD
This study looks at different lung immune cell patterns and how they work in smokers who are not yet diagnosed with COPD or asthma. It may help researchers understand why some people are more likely to develop COPD, which could guide future prevention or early treatments.
San Francisco, CaliforniaAges 40–75 - NCT04918095Recruiting
COPD home monitoring with a phone or tablet
This study tests a home monitoring program for people with COPD (a long-term lung condition) to track symptoms using a phone or tablet. It may help clinicians spot changes earlier and improve how COPD care is managed.
Ventura, CaliforniaAges 40–100 - NCT05008081Recruiting
Study for COPD flare-ups given standard rescue medicines
This study looks at people hospitalized for a COPD flare-up (“exacerbation”). It may help improve how flare-ups are treated because participants need to receive the usual rescue medicines like steroids and/or antibiotics and then follow a study plan.
LinzAges 18 years+ - NCT05061368RecruitingPhase 2
Sildenafil by mouth to improve breathing in COPD
This Phase 2 trial tests whether sildenafil tablets can improve exercise ability, shortness of breath, and heart-lung function in people with COPD. It also compares against people without COPD to better understand how sildenafil affects breathing tests.
Edmonton, AlbertaAges 40–80
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,253 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.