Clinical trials
Chronic Disease clinical trials
Below are recruiting chronic disease clinical trials, each written for real people, not researchers. We’re tracking 1,253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05196698Recruiting
Home high-flow oxygen after COPD hospital flare
This study tests whether using a special oxygen device at home helps prevent another acute COPD flare after you’ve been hospitalized. It’s mainly for people with severe breathing problems who may need oxygen support long-term.
RouenAges 18–85 - NCT05237505RecruitingPhase 2
Sleep apnea plus COPD study to check heart and breathing effects
This Phase 2 study looks at the cardiovascular (heart/blood vessel) effects of having both sleep apnea and COPD. It may help doctors better understand who is at risk and how to manage these breathing problems together.
La Jolla, CaliforniaAges 40–79 - NCT05297279Recruiting
Omega-3 diet program for people with COPD
This trial tests whether increasing omega-3 (from diet and/or supplements) helps people with COPD. It enrolls people with low omega-3 intake and asks them to follow a specific dietary plan during the study.
Baltimore, MarylandAges 40 years+ - NCT05306743Recruiting
Quality program for high-risk COPD, tested with primary care teams
This study looks at how well a quality-improvement program (called CONQUEST) helps people with higher-risk chronic lung disease (COPD) when delivered through primary care teams. It compares the program given right away versus usual care for a while, then the program later.
Denver, ColoradoAges 18 years+ - NCT05399056Recruiting
Peer support and storytelling to help COPD lung rehab
This study aims to improve how well people with COPD can take part in pulmonary rehabilitation by using peer coaching and short storytelling videos. If you recently had a COPD flare and are being referred to lung rehab, this may offer extra support to help you complete the program.
Springfield, MassachusettsAges 40 years+ - NCT05437198Recruiting
Breath sample study comparing lung bacteria in and out of COPD
This study looks at the germs in exhaled (breathed-out) air to compare people with COPD to people without COPD. It may help researchers better understand lung differences and what could drive COPD.
CréteilAges 18–70 - NCT05495698Recruiting
One or multiple inhalers plus app support for COPD
This trial looks at whether using one or more inhalers, together with a smartphone app, can help people manage chronic obstructive pulmonary disease (COPD) better. You may be eligible if you have COPD, need “triple therapy” (three medicine types), and can use the app and surveys.
Rotterdam, South HollandAges 40 years+ - NCT05572632Recruiting
COPD wellness rehab program for safety-net patients
This trial studies a COPD (chronic lung disease) wellness and rehabilitation program for people who get care through the safety-net health system. It may help improve day-to-day outcomes by supporting safer exercise and better COPD management.
San Francisco, CaliforniaAges 40–90 - NCT05581368Recruiting
Study how cannabis affects blood vessels
This trial tests whether regular cannabis use changes how your blood vessels work, compared with people who do not use cannabis. It may help researchers understand potential effects on heart and circulation health.
London, OntarioAges 19–80 - NCT05652439Recruiting
Assess heart and stroke events after starting triple COPD inhalers
This study looks at how often heart problems or stroke happen in people with COPD after they start a specific “triple therapy” inhaler. It may help doctors understand whether these inhalers change cardiovascular (heart) or cerebrovascular (stroke) risk.
LondonAges 40 years+ - NCT05697159Recruiting
7-tesla brain MRI to study how filgotinib eases RA pain
This trial uses a very high-strength brain MRI to understand how the RA medicine filgotinib may reduce pain. If you have active rheumatoid arthritis and can safely complete the scan, the study may help researchers better target pain relief in RA.
GlasgowAges 18–74 - NCT05703919RecruitingPhase 4
Compare standard vs targeted oxygen for COPD flare-ups
This trial tests whether giving oxygen in a standard way or a more targeted way helps people who are having a COPD flare-up before they reach the hospital. It may help reduce oxygen-related harms while still treating low oxygen during emergency care.
Aarhus NAges 40 years+ - NCT05717192Recruiting
Bronchoscopy treatment to shrink severe emphysema using heat
This trial studies a bronchoscopy procedure that uses heat (thermoablation) to reduce over-inflated lung tissue in people with severe emphysema. If you qualify, it aims to improve breathing and walking ability after trying standard treatments first.
BerlinAges 40–75 - NCT05743582Recruiting
Studying natural immunity in COPD and in healthy adults
This study looks at how the body’s “innate” (first-line) immune system works in people with COPD compared with healthy volunteers. It may help researchers understand COPD inflammation and how immune responses could be targeted in the future.
EdinburghAges 18–77 - NCT05772013RecruitingPhase 4
Checking azithromycin prevention for COPD flare-ups
This Phase 4 study looks at optimizing how people with COPD take azithromycin to reduce flare-ups (exacerbations). If you already take azithromycin regularly, the trial may test ways to improve how it’s used safely.
CambridgeAges 40 years+ - NCT05785026Recruiting
Menthol to reduce breathlessness in COPD and healthy adults
This trial tests whether menthol helps with breathlessness (dyspnea) during exercise. You may be asked to do breathing and exercise tests, and to use menthol under study supervision to see if symptoms improve.
LeuvenAges 18 years+ - NCT05896579Recruiting
Study heart function during rest and exercise in COPD
This study measures how well the right side of your heart works when you are resting and when you exercise, in people with chronic obstructive pulmonary disease (COPD). It may help researchers better understand COPD-related heart strain and guide future care.
Aurora, ColoradoAges 40 years+ - NCT05928169Recruiting
Tracking how inflammatory skin conditions change over time
This study looks at what affects the “path” (trajectory) of long-lasting inflammatory skin conditions. It may help researchers understand why symptoms change and how treatments or factors influence those changes.
KielAges birth–80 years - NCT05937854RecruitingPhase 2
Tadalafil to help breathing in COPD with pulmonary hypertension
This Phase 2 study tests whether tadalafil can improve breathlessness in people with COPD and pulmonary hypertension (high blood pressure in the lungs). It may help you breathe more easily if your symptoms are driven by this specific lung circulation problem.
Aurora, ColoradoAges 35–89 - NCT05989698Recruiting
Validating a wearable cough monitor (C-mo)
This study tests a wearable device (C-mo) that monitors coughing. It is for people of all ages who are currently coughing and can cooperate with wearing a small sensor on their belly for a short time.
AlfenaAges 2 years+ - NCT06068322Recruiting
Very intense interval training for people with COPD
This study tests whether a very intense, short burst of exercise (supramaximal high-intensity interval training) is safe and effective for people aged 60 and older with or without COPD. It aims to see if this type of exercise can improve fitness and daily life.
Hasselt, DiepenbeekAges 60 years+ - NCT06163131Recruiting
How endobronchial valves affect diaphragm movement in emphysema
This trial measures how well your diaphragm (the main breathing muscle) moves after you get endobronchial valves (tiny one-way valves in your airways) for emphysema. It helps doctors see if the valves improve your breathing muscle function.
AarhusAges 18 years+ - NCT06188065Recruiting
Eosinopenia and Recovery in Severe COPD Exacerbation
This study is looking at people admitted to the hospital for a severe COPD flare-up. It checks if a low level of eosinophils (a type of white blood cell) in the blood is linked to how quickly you recover from the flare-up.
North ShieldsAges 35 years+ - NCT06201403Recruiting
COPD: Breathing Muscle Strength and Flexibility Study
This study looks at the strength and flexibility of muscles you use to breathe, including muscles in your chest and neck. If you have moderate-to-severe COPD and have been stable on your medications, it may help researchers understand how these muscles are affected.
Istanbul, ZeytinburnuAges 18–75
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Common questions
- Are there clinical trials for chronic disease?
- Yes. Clin2 currently lists 1,253 recruiting chronic disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.