Clinical trials
Chronic Kidney Disease Stage 4 clinical trials
Below are recruiting chronic kidney disease stage 4 clinical trials, each written for real people, not researchers. We’re tracking 147 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05858437Recruiting
Testing propionic acid to improve immune function in children with kidney failure
This study tests whether propionic acid can help the immune system work differently in children with advanced chronic kidney disease who receive regular dialysis. It may help regulate immune cells, aiming for better immune function while keeping you medically stable.
BerlinAges 12–20 - NCT05944016RecruitingPhase 3
Dapagliflozin for early Alport kidney disease in teens and young adults
This trial tests dapagliflozin, a daily medicine, to slow kidney problems in people with early-stage chronic kidney disease caused by Alport syndrome. It may help protect kidney function and reduce worsening over time.
Heidelberg, Baden-WürttenbergAges 10–39 - NCT05970172RecruitingPhase 3
Roxadustat for anemia in kids with chronic kidney disease
This study tests roxadustat, a medicine that helps the body make more red blood cells, in children and teens with anemia caused by chronic kidney disease. It may help improve anemia and related blood counts, while also monitoring safety.
BrusselsAges 2–17 - NCT06001827Recruiting
Study of a wrap to help new dialysis access points heal
This trial tests a special wrap placed around a new arm access point for dialysis (called an AV fistula) to see if it helps the access stay healthy and work better. It is for people who need a new AV fistula for kidney dialysis.
Bullhead City, ArizonaAges 18 years+ - NCT06155604RecruitingPhase 2
SGLT2 inhibitor for lupus nephritis with kidney disease
This study tests if an SGLT2 inhibitor can help protect kidney function in people who have lupus nephritis (kidney inflammation caused by lupus) and chronic kidney disease (CKD). The goal is to see if this medicine can slow down further kidney damage.
Hong KongAges 18 years+ - NCT06173323Recruiting
Improving decision-making for kidney disease patients and their caregivers
This study tests a program to help people with advanced chronic kidney disease (stage 4 CKD) and their caregiver work together on medical decisions. It aims to see if the program improves communication and partnership.
Birmingham, AlabamaAges 18 years+ - NCT06224153Recruiting
Tracking Protein Intake in Advanced Kidney Disease
This study compares two ways to track how much protein you eat using a mobile app or website. It is for people with advanced chronic kidney disease who are already in a nutrition program and want to follow a low-protein diet.
Marseille, FranceAges 18 years+ - NCT07694791Recruiting
Gut health supplements for people on peritoneal dialysis
This trial tests whether taking probiotic and prebiotic supplements can improve gut health in people receiving peritoneal dialysis at home. It may help with digestion and overall well-being.
Monterrey, Nuevo LeónAges 18 years+ - NCT06383208Recruiting
Heart and kidney risk study for people with both diseases
This study looks at how well we can predict heart and kidney problems in people who have both coronary heart disease and chronic kidney disease. By analyzing certain markers, researchers hope to create a better risk assessment tool.
Beijing, Beijing MunicipalityAges 18–80 - NCT06463483Recruiting
Automated Insulin Delivery for People with Advanced Kidney Disease
This trial tests an automated insulin pump system for people with diabetes who also have advanced kidney disease. It may help manage blood sugar more easily.
LondonAges 18–70 - NCT06542016Recruiting
Heart risk prediction in dialysis patients using a questionnaire
This study looks at how a simple questionnaire (called KCCQ) about your heart health and quality of life can help predict future heart risks for people on dialysis. Researchers want to see if your answers to this questionnaire can help doctors take better care of you.
Guangdong, GuangdongAges 18 years+ - NCT07592000RecruitingPhase 1/Phase 2
New Treatment for Type 1 Diabetes With Kidney Disease
This study tests a new experimental medication for people with type 1 diabetes who experience dangerous low blood sugar episodes and have early-stage kidney disease. The trial aims to help improve blood sugar control and reduce these risky episodes.
Chicago, IllinoisAges 18–70 - NCT06621264Recruiting
Exercise study to improve walking in kidney and artery disease
This trial tests whether a supervised exercise program can help people with chronic kidney disease and peripheral artery disease walk better and feel stronger. It aims to improve mobility and quality of life.
Ferrara, ItalyAges 18–80 - NCT06660277Recruiting
Dialysis with expanded solute removal study
This trial tests a special dialysis filter (Elisio HX) that removes more waste products from the blood. It aims to see if this approach improves health outcomes for people on regular in-center hemodialysis.
London, OntarioAges 45 years+ - NCT06671535Recruiting
Dialysis filter for itching in hemodialysis patients
This study tests a special type of dialysis filter (made of PMMA) to see if it can reduce severe itching and improve quality of life for people on long-term dialysis. If you have bothersome itching that standard treatment hasn't helped, this trial might be an option for you.
Saint PetersburgAges 18 years+ - NCT07613593Recruiting
Digital kidney disease care platform evaluation study
This study evaluates whether MyRenalCare, a digital platform that helps patients with chronic kidney disease (CKD) monitor and manage their condition, improves health outcomes and patient experience. Researchers will compare people using the platform with those receiving standard care, and interview patients and staff about their experiences.
Portsmouth, HampshireAges 18 years+ - NCT06725810RecruitingPhase 4
Enarodustat for anemia in chronic kidney disease (not on dialysis)
This trial tests enarodustat, a pill for anemia, in people with chronic kidney disease who are not on dialysis. It aims to see if it can safely raise hemoglobin levels.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06799936Recruiting
Helping older kidney patients decide on treatment with their doctor
This trial tests a program that helps older adults with advanced kidney disease talk with their doctors about treatment options. The goal is to improve shared decision-making before they need dialysis or a transplant.
Hong KongAges 65 years+ - NCT06858280RecruitingPhase 3
Patiromer and diet for potassium in dialysis patients
This trial tests if a medication called patiromer, combined with a low-potassium diet, can help manage potassium levels in people on chronic dialysis. The goal is to improve quality of life by allowing a more flexible diet.
Bergamo, BGAges 18 years+ - NCT06897605RecruitingPhase 2
Dapagliflozin for anemia in kidney disease
This trial tests whether a medication called dapagliflozin can help improve anemia in people with chronic kidney disease. If you have moderate to severe kidney disease and low red blood cell counts despite taking standard anemia treatment, this study may explore a new option.
Al MansurahAges 18 years+ - NCT06933108Recruiting
Predicting Nerve Damage with Simple Function Tests
This study looks at whether simple function tests can predict nerve damage in people with advanced kidney disease or diabetes. It aims to find early signs of nerve problems before they become serious.
Le MansAges 60–80 - NCT06933472RecruitingPhase 3
Study of a new phosphate binder for dialysis patients
This trial tests a new drug called AP301 to lower high phosphate levels in people on dialysis. It's designed to help control phosphate, which can be hard to manage with diet and current medications.
Granada Hills, CaliforniaAges 12 years+ - NCT06935786Recruiting
Sedentary lifestyle and health risks in kidney disease
This study looks at how a sedentary (mostly sitting or lying down) lifestyle affects people with advanced chronic kidney disease. It aims to see if being less active is linked to higher risks of death or major health problems.
PoriAges 40 years+ - NCT06940414Recruiting
Study of high potassium in kidney disease patients in community
This study looks at how common high potassium levels are in people with chronic kidney disease who are not on dialysis. It may help find who is at risk and how to prevent it.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for chronic kidney disease stage 4?
- Yes. Clin2 currently lists 147 recruiting chronic kidney disease stage 4 studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic kidney disease stage 4 trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic kidney disease stage 4 trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.