Clinical trials
Chronic Low Back Pain clinical trials
Below are recruiting chronic low back pain clinical trials, each written for real people, not researchers. We’re tracking 268 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07766200Recruiting
Pain types in people with long-term low back pain
This study looks at different types of chronic low back pain. It aims to understand how pain affects people differently, which might help improve future treatments.
Kütahya, TürkiyeAges 18–70 - NCT07760142Recruiting
Electrical stimulation with core exercise for chronic low back pain
This study tests whether adding electrical stimulation to a core exercise program helps relieve chronic low back pain. You would attend two sessions a week for six weeks.
ŞırnakAges 18–55 - NCT07742111Recruiting
Virtual reality for long-term low back pain
This study tests whether virtual reality exercises can help people with chronic low back pain feel better and move more comfortably. You might join if you have had low back pain for a while, your pain is moderate, and you have some fear of movement.
AmaranteAges 18 years+ - NCT07731750Recruiting
Smart pain treatment plan for chronic low back pain
This study tests a computer-based tool to help choose the best pain treatments for people with chronic low back pain. It compares different treatments to see which ones work best for each person.
Ann Arbor, MichiganAges 25 years+ - NCT07731269Enrolling by invitation
Kinesiology taping for acute low back pain
This study tests if kinesiology tape (a special stretchy tape placed on the skin) can help relieve pain and improve movement in people with sudden, short-term low back pain. It may be an option if your pain just started and you haven't had long-term back issues.
IstanbulAges 18–50 - NCT07724704Recruiting
Exercise comparison for long-term low back pain
This study compares two sets of exercises (called McGill and Sahrmann) to see which is better at reducing chronic low back pain. If you have had non-specific low back pain for more than 12 weeks, this trial may help you strengthen your core and feel better without surgery or medication.
Lahore, Punjab ProvinceAges 20–50 - NCT07719452Enrolling by invitation
Strengthening exercise for chronic low back pain
This study tests if adding a specific low back strengthening exercise to standard physical therapy helps people with long-lasting low back pain. It is for Tricare beneficiaries who have had back pain for at least 3 months without leg pain.
Fort Sam Houston, TexasAges 18–65 - NCT07719699Recruiting
Vibration and Pilates for chronic low back pain
This study tests if whole-body vibration or Pilates exercises can reduce pain and improve balance and movement in people with long-lasting low back pain. It aims to find a helpful treatment for chronic back pain that has lasted more than 12 weeks.
Lahore, Punjab ProvinceAges 18–40 - NCT07712406Recruiting
Nerve block for lower back pain from nerve entrapment
This trial tests whether a nerve block can help people with chronic lower back or buttock pain caused by a trapped nerve near the hip bone. You may be eligible if you have had this pain for at least 3 months and it did not get better with other treatments.
Gaziosmanpaşa, IstanbulAges 18–75 - NCT07709416Recruiting
Testing toludesvenlafaxine for long-lasting low back pain
This study tests an experimental medication called toludesvenlafaxine to see if it can help people with long-lasting low back pain that has no clear cause. If you have moderate to severe lower back pain for more than 3 months and haven't taken antidepressants before, this may be an option for you to explore.
BeijingAges 18–75 - NCT07693998Enrolling by invitation
Pain education class for fibromyalgia or chronic back pain
This trial tests a class to help people with fibromyalgia or chronic low back pain learn about their pain and how to manage it. It might help you feel better and understand your pain.
Valencia, ValenciaAges 18 years+ - NCT07696741Recruiting
Pain Reprocessing Therapy for Chronic Lower Back Pain
This study tests a type of talk therapy called pain reprocessing therapy (PRT) for adults with chronic lower back pain. The goal is to see if PRT can help reduce pain and improve quality of life.
Toronto, OntarioAges 18–65 - NCT07688915Recruiting
High-intensity laser vs. steroid injection for chronic back and leg pain from a herniated disc
This study compares two treatments for long-lasting low back and leg pain caused by a herniated disc: high-intensity laser therapy and a steroid shot near the spine. Researchers want to see which option works better to reduce pain.
AnkaraAges 18–65 - NCT06656156Recruiting
Stretching technique for chronic low back pain relief
This trial tests a physical therapy stretching method called PNF on the hip and hamstring muscles to see if it reduces chronic low back pain. It may help if you have had non-specific low back pain for over 3 months with tightness in your hips or legs.
Karachi, SindhAges 15–40 - NCT07685340Recruiting
Cupping vs Massage Tool for Chronic Low Back Pain
This trial tests two hands-on therapies—dry cupping and a special massage technique—to see which works better for long-term low back pain caused by muscle knots. You may be able to join if your pain has lasted over 3 months and you have trigger points.
Rawalpindi, Punjab ProvinceAges 25–45 - NCT07684118Enrolling by invitation
Egoscue vs core exercises for chronic low back pain
This study compares two types of exercises—Egoscue and core stabilization—to help people with chronic low back pain and an exaggerated lower back curve. The goal is to find which approach better reduces pain and improves function.
Lahore, Punjab ProvinceAges 25–55 - NCT07681336Recruiting
Ear nerve stimulation for chronic low back pain
This trial tests if stimulating the vagus nerve through the ear can reduce chronic low back pain in people who haven't gotten enough relief from painkillers. It aims to see if this non-invasive treatment can help manage pain without medication.
Ghent, Oost-VlaanderenAges 30–60 - NCT07675304RecruitingEarly Phase 1
Mesotherapy for chronic low back pain study
This trial tests whether injecting a natural substance (collagen) into the lower back can safely reduce chronic pain. It may help people with pain that hasn't spread to the legs.
WarsawAges 18–65 - NCT06671132RecruitingPhase 2
Computer training for pain relief using smell exercises
This trial tests a computer program that uses smell training to help people with chronic low back pain. It aims to reduce pain by retraining brain connections.
Washington D.C., District of ColumbiaAges 18–85 - NCT07652944Recruiting
Magnetic field therapy for chronic lower back pain
This trial tests whether magnetic fields applied to your back can relieve chronic lower back pain that has lasted at least 12 weeks. It's for people aged 18 to 64 who are willing to attend all study visits.
Edwards Air Force Base, CaliforniaAges 18–64 - NCT07641504RecruitingPhase 2
Testing LY4065967 for chronic low back pain relief
This study tests whether a new medication called LY4065967 can reduce chronic low back pain. Researchers want to see if it works better than current treatments for people who have had lower back pain for at least 3 months.
Birmingham, AlabamaAges 18 years+ - NCT07639060Recruiting
Pain Relief Study Using Freezing Nerve Treatment
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
Old Saybrook, ConnecticutAges 18 years+ - NCT07645859Recruiting
High-Intensity vs. Moderate Exercise for Chronic Lower Back Pain
This trial compares two types of exercise programs—one with short, intense bursts of activity and one with steady, moderate activity—to see which works better for people with long-lasting lower back pain that has no clear medical cause. You would participate in supervised exercise sessions over several weeks.
KarachiAges 20–48 - NCT07636967Recruiting
Ankle Muscle Strength in Chronic Low Back Pain
This study measures the strength and function of ankle muscles in people with chronic low back pain lasting over 3 months. Understanding how ankle muscles work may help explain why some people develop long-term low back pain.
Tanta, Gharbia GovernorateAges 20–25
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Common questions
- Are there clinical trials for chronic low back pain?
- Yes. Clin2 currently lists 268 recruiting chronic low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.