Clinical trials
Chronic Low Back Pain clinical trials
Below are recruiting chronic low back pain clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03168802Recruiting
Ultrasound and nerve treatment for facet-joint low back pain
This study tests whether a procedure that uses focused ultrasound (MRgFUS) and/or a radiofrequency nerve treatment can reduce long-lasting low back pain caused by facet-joint arthritis. It may help people whose pain improves strongly after a targeted numbing injection to specific back nerves.
Taipei, Please SelectAges 20–79 - NCT06517342Recruiting
Using a health app for low back pain
This study looks at what helps or stops people with chronic low back pain from using a smartphone app to become more active. It aims to find ways to make it easier for you to stay active.
Clermont-FerrandAges 18 years+ - NCT06384001Recruiting
Meditation for chronic low back pain in older adults
This trial tests whether a meditation program can help reduce chronic low back pain in adults aged 50 and older. You'll learn meditation techniques that you can do at home using an internet connection, and the study will track how your pain changes over time.
Tallahassee, FloridaAges 50–89 - NCT07111286Recruiting
Imagining movements to help chronic low back pain
This trial tests whether imagining movements (motor imagery) can help improve daily function and reduce pain in people with chronic low back pain. You will participate in a rehabilitation program, and if you are in the motor imagery group, you will also practice mentally rehearsing specific movements.
DijonAges 18 years+ - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT06806514Recruiting
Exercise and muscle strength in chronic low back pain
This trial measures how well you can use your arms and how strong your breathing and other muscles are if you have chronic low back pain. It aims to understand the links between these factors to improve future treatments.
KırşehirAges 18–65 - NCT07286630Enrolling by invitation
Disability and fear avoidance in physical therapists
This study looks at how common disability and fear-related beliefs are among Egyptian physical therapists who have long-term low back pain. If you qualify, you will answer questionnaires about your pain, your thoughts about movement, and how it affects your daily life.
CairoAges 25–55 - NCT07215104Recruiting
Spinal cord stimulation for chronic low back pain
This trial tests a special type of spinal cord stimulation (called BurstDR) in people with chronic low back pain. If you already have a spinal cord stimulator and it helps your pain, researchers want to see if adding muscle stimulation can provide even more relief.
Charleston, West VirginiaAges 18 years+ - NCT07551323Recruiting
Myofascial Release vs. Pilates for Chronic Low Back Pain
This study compares two hands-on treatment approaches—myofascial release (deep tissue massage) and Pilates exercises—to see which works better for chronic low back pain that isn't caused by nerve damage. If you have persistent lower-back pain, this trial might help you find relief through one of these therapies.
Istanbul, IstanbulAges 18–45 - NCT07132762Recruiting
Shock wave therapy for chronic low back pain
This study tests whether adding a special sound wave therapy (called ESWT) to standard care (like exercise and education) can reduce pain and improve daily function in people with long-term low back pain. It is designed for people whose back pain does not have a specific known cause.
DenizliAges 18–65 - NCT06724679Recruiting
Virtual reality for chronic back pain treatment
This trial tests if using a virtual reality (VR) headset can help people with long-term lower back pain during a spine rehabilitation program. It will see if VR is a practical and helpful addition to the program.
AngersAges 18–65 - NCT07559890Recruiting
Nerve ablation for low back pain with Modic changes
This study tests a procedure that uses heat to stop a nerve in the lower back from sending pain signals. It may help people with long-term central low back pain who have not gotten better with other treatments and have Modic changes on MRI.
PragueAges 18 years+ - NCT06113185Recruiting
Pain Scale Study for Low Back Pain
This study tests a pain scale for people with long-term low back pain. It is a questionnaire study, not a treatment trial, so you will fill out forms about your pain.
Istanbul, None SelectedAges 18–55 - NCT07712406Recruiting
Nerve block for lower back pain from nerve entrapment
This trial tests whether a nerve block can help people with chronic lower back or buttock pain caused by a trapped nerve near the hip bone. You may be eligible if you have had this pain for at least 3 months and it did not get better with other treatments.
Gaziosmanpaşa, IstanbulAges 18–75 - NCT07719699Recruiting
Vibration and Pilates for chronic low back pain
This study tests if whole-body vibration or Pilates exercises can reduce pain and improve balance and movement in people with long-lasting low back pain. It aims to find a helpful treatment for chronic back pain that has lasted more than 12 weeks.
Lahore, Punjab ProvinceAges 18–40 - NCT06310226Recruiting
Studying spinal cord stimulation for chronic low back pain
This study is looking at how people with chronic low back pain respond to spinal cord stimulation (a device that sends gentle electrical pulses to the spine to reduce pain). If you already have a spinal cord stimulator, you may help researchers understand how well it works and how it affects your brain.
Los Angeles, CaliforniaAges 18–80 - NCT06471920Recruiting
Telerehab for chronic low back pain in rural areas
This study tests whether a video-based physical therapy program can help people with chronic low back pain who live in rural areas. If you qualify, you'll get telerehabilitation (rehab done at home through video calls) to reduce pain and improve function.
Baltimore, MarylandAges 18 years+ - NCT06025201Recruiting
Brain activity markers for chronic low back pain
This study uses a safe, non-invasive cap with sensors (EEG) to measure your brain activity and look for patterns linked to chronic low back pain. It aims to better understand pain so doctors can improve treatments.
Palo Alto, CaliforniaAges 18–80 - NCT05780021Recruiting
Support program for long-term low back pain after rehab
This trial tests whether a structured motivational support program can help people with long-term low back pain after they finish a rehab program. It may help you stay motivated and improve your day-to-day progress after treatment.
ParisAges 18 years+ - NCT07415941Recruiting
Mindfulness and nerve stimulation for back pain and depression
This trial tests if combining mindfulness-based meditation with a gentle nerve stimulation device (applied to the ear) can help people aged 50–85 with chronic low back pain and depression. The goal is to reduce pain and improve mood without changing your current medications.
Tallahassee, FloridaAges 50–85 - NCT05880212Recruiting
STOPS low back and leg pain approach for Bangladesh
This trial tests a specific physiotherapy program (“STOPS approach”) for people with long-lasting low back pain or leg pain from the back. It aims to see if the structured treatment, delivered by trained physiotherapists, improves pain and function over about 10 weeks.
Dhaka, UttaraAges 18–65 - NCT06453291Recruiting
Comparing treatments for chronic low back pain
This study compares different ways to treat chronic low back pain that has lasted more than 3 months. It aims to find which approach works best for adults aged 40 to 60.
LahoreAges 40–60 - NCT06491121Recruiting
Can high-intensity training with a smartphone help chronic back pain?
This trial tests if a technology-supported high-intensity exercise program can help adults with chronic low back pain. You'll use your own smartphone to help guide the training and attend regular therapy sessions.
Wilrijk, AntwerpenAges 18–65 - NCT07277517Recruiting
Pain education plus physical therapy for new back pain
This study tests whether adding Pain Neuroscience Education (learning how your brain and nerves process pain) to standard physical therapy can help people with new low back pain feel better and move more easily. It's for adults whose pain started within the past 6 weeks and who do not have a serious spine condition.
TehranAges 18 years+
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Common questions
- Are there clinical trials for chronic low back pain?
- Yes. Clin2 currently lists 270 recruiting chronic low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.