Clinical trials
Chronic Low Back Pain clinical trials
Below are recruiting chronic low back pain clinical trials, each written for real people, not researchers. We’re tracking 268 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07306312Enrolling by invitation
How thoughts affect low back pain with manual therapy
This study looks at how your thoughts and feelings about your chronic low back pain affect your pain and ability to move, during a course of manual therapy (hands-on treatment by a therapist). It may help you understand if your mindset influences your recovery.
AthensAges 18–65 - NCT07298109Recruiting
Diaphragm Release for Chronic Low Back Pain
This study tests if releasing tension in the diaphragm muscle can help reduce chronic low back pain. It may be a treatment option for people whose back pain has lasted at least 12 weeks and has no clear cause.
KarabükAges 18–65 - NCT07298941RecruitingPhase 2
Sleep treatment to help with chronic low back pain
This study tests if improving sleep can help people with chronic low back pain feel better and cope with pain. It involves a sleep-focused treatment program and looks at how it affects your overall well-being.
Charlottesville, VirginiaAges 18 years+ - NCT07304076Recruiting
JHG002 Injection for Chronic Low Back Pain
This study tests if JHG002 injections (made from human placenta) are safe and effective for treating chronic low back pain. It may help people who have had low back pain for at least 6 months and rate their pain as a 5 or higher on a 0–10 scale.
Seoul, Gangdong-guAges 19–70 - NCT07296653RecruitingEarly Phase 1
Prolotherapy for chronic low back pain
This trial tests a treatment called prolotherapy, which uses injections of a sugar solution into specific acupuncture points to help relieve chronic low back pain. It is for people who have had low back pain for at least 3 months, have not had previous back surgery, and have not received similar injections recently.
Athens, AtticaAges 35 years+ - NCT07286630Enrolling by invitation
Disability and fear avoidance in physical therapists
This study looks at how common disability and fear-related beliefs are among Egyptian physical therapists who have long-term low back pain. If you qualify, you will answer questionnaires about your pain, your thoughts about movement, and how it affects your daily life.
CairoAges 25–55 - NCT07284407Recruiting
Learning about pain and touch training for long-term back pain
This study tests two types of therapy for ongoing low back pain: learning about how pain works (pain education) and training your sense of touch (sensory discrimination). The goal is to help your brain process pain better and reduce discomfort.
LahoreAges 19–44 - NCT05706103Recruiting
Exercise therapy for recurrent low back pain with brain changes
This trial studies whether a specific exercise program can improve recurrent low back pain by changing activity in muscles and the brain. If you have non-specific low back pain that comes and goes over time, you may be asked to do exercises and undergo brain and muscle testing (including MRI).
Ghent, Oost-VlaanderenAges 18–45 - NCT07277517Recruiting
Pain education plus physical therapy for new back pain
This study tests whether adding Pain Neuroscience Education (learning how your brain and nerves process pain) to standard physical therapy can help people with new low back pain feel better and move more easily. It's for adults whose pain started within the past 6 weeks and who do not have a serious spine condition.
TehranAges 18 years+ - NCT06679205Recruiting
Multidisciplinary care for long-term low back pain
This study tests a team-based, non-drug treatment program for long-term low back pain. It combines physical therapy, education, and support to help reduce pain and improve daily function.
Barcelona, BarcelonaAges 18 years+ - NCT07251959Enrolling by invitation
Exercise vs. exercise plus manual therapy for chronic back pain
This study tests whether a workplace exercise program, with or without hands-on manual therapy, can help reduce chronic spinal pain in desk workers. It is designed for UCAM University staff who have had persistent back pain for at least 3 months.
Murcia, MurciaAges 18 years+ - NCT07248813Recruiting
Home-based rehab program for chronic low back pain
This trial tests a telerehabilitation program you can do from home using a smartphone or computer. It aims to improve function and reduce pain for people with chronic low back pain compared to usual care.
México, TexcocoAges 18–60 - NCT07241559Recruiting
Low back pain treatment study: injection and mobilization
This study tests two treatments for chronic low back pain: a special injection of dextrose (a sugar solution) guided by ultrasound, and a technique to mobilize the fascia (connective tissue) in the lower back. It aims to see if these help people who haven't found relief from standard treatments.
Ankara, AltındağAges 18–65 - NCT07222462Recruiting
Radiofrequency ablation for chronic low back pain
This study tests if radiofrequency ablation, a procedure that uses heat to block pain signals from the facet joints in your spine, can help people with long-term low back pain that hasn't improved with other treatments like physical therapy.
Atlanta, GeorgiaAges 18 years+ - NCT07216417Recruiting
Virtual yoga for chronic low back pain
This study tests whether a virtual yoga program can help reduce chronic low back pain. You'll attend online yoga classes from home, and the study will also ask about your experience.
Kansas City, KansasAges 30–80 - NCT07214844Recruiting
Freezing vs. heating nerves for chronic low back pain
This study compares two procedures to treat long-term low back pain from the small joints in your spine. One uses extreme cold, the other uses heat to stop pain signals. It may help if you have had at least three months of back pain and other treatments haven't worked.
The Bronx, New YorkAges 18 years+ - NCT07215104Recruiting
Spinal cord stimulation for chronic low back pain
This trial tests a special type of spinal cord stimulation (called BurstDR) in people with chronic low back pain. If you already have a spinal cord stimulator and it helps your pain, researchers want to see if adding muscle stimulation can provide even more relief.
Charleston, West VirginiaAges 18 years+ - NCT06915896Recruiting
Chronic back or neck pain: predicting therapy outcomes
This study looks at people with long-term low back or neck pain who are waiting for physical therapy. It aims to find what factors predict how well they will do with different treatment paths.
Florence, FIAges 18 years+ - NCT06347991Recruiting
Chiropractic self-care app study for back pain in Alberta
This study tests an app called SelfBack that helps chiropractic patients manage their own long-term low back pain. You will use your smartphone to receive personalized exercises and tips. It may help you take control of your back pain between chiropractic visits.
Edmonton, AlbertaAges 18 years+ - NCT07207083Enrolling by invitation
Can virtual reality exercise help restore body and mind in chronic low back pain
This trial tests whether doing exercises in a virtual reality (VR) environment can help people with chronic low back pain feel better both physically and mentally. You would use a VR headset to perform gentle movements and see how it affects your pain and fear of moving.
Seoul, SeoulAges 18–40 - NCT07211464Recruiting
ACT plus exercise for older adults with chronic low back pain
This study tests whether combining acceptance and commitment therapy (ACT) with exercise helps older adults manage ongoing low back pain. If you've had pain for at least 3 months and it's been bothering you, this approach might teach you new ways to cope and move better.
Hong KongAges 60 years+ - NCT07195422Recruiting
Study of a new device for low back pain relief
This trial tests a wearable device called Japet.W+ to see if it can help reduce chronic low back pain. It might be an option for people who have had lower back pain for a long time and are looking for non-surgical relief.
Clermont-FerrandAges 18–80 - NCT06544525Recruiting
Pain test to predict physical therapy results for back pain
This trial tests whether a simple pain test can predict how much you will improve with physical therapy for chronic low back pain. It looks at how your body naturally handles pain, which may help tailor your treatment.
Fort Sam Houston, TexasAges 18–64 - NCT07198412Recruiting
Study on sedation's effect on back pain after spinal anesthesia
This study looks at whether giving sedation (medicine to help you relax) during spinal anesthesia can reduce back pain after surgery. It's for people having certain types of surgery on their lower abdomen or legs.
Banhā, Qalyubia GovernorateAges 18–65
Hear when a new Chronic Low Back Pain trial opens
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Common questions
- Are there clinical trials for chronic low back pain?
- Yes. Clin2 currently lists 268 recruiting chronic low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.