Clinical trials
Chronic Low Back Pain clinical trials
Below are recruiting chronic low back pain clinical trials, each written for real people, not researchers. We’re tracking 270 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07244913Recruiting
Tools for chronic low back pain relief
This trial compares two types of handheld tools—one with metal instruments and one that uses sound waves—to see which works better for long-term low back pain. It may help if you have had pain for at least 6 months and feel tightness in your hamstrings.
Lahore, Punjab ProvinceAges 40–55 - NCT06355414RecruitingPhase 1
Psilocybin for chronic back pain and depression
This trial tests if psilocybin, a psychedelic drug, can help people with long-term low back pain who also have depression. If you qualify, you'll receive psilocybin in a controlled setting, and researchers will see how it affects your pain and mood.
Baltimore, MarylandAges 21–80 - NCT07193212Recruiting
Osteopathic treatment for low back pain and leg health
This study tests whether a hands-on osteopathic treatment can improve how your legs and feet work if you have chronic low back pain. It may help you understand if this type of manual therapy is a good option for your pain.
Auburn, AlabamaAges 18–65 - NCT07028034Recruiting
Six-minute step test for chronic back pain
This trial uses a simple step test to measure how chronic low back pain affects your daily function. It may help doctors better understand your condition without needing expensive equipment.
KırşehirAges 18–65 - NCT07719452Enrolling by invitation
Strengthening exercise for chronic low back pain
This study tests if adding a specific low back strengthening exercise to standard physical therapy helps people with long-lasting low back pain. It is for Tricare beneficiaries who have had back pain for at least 3 months without leg pain.
Fort Sam Houston, TexasAges 18–65 - NCT07731269Enrolling by invitation
Kinesiology taping for acute low back pain
This study tests if kinesiology tape (a special stretchy tape placed on the skin) can help relieve pain and improve movement in people with sudden, short-term low back pain. It may be an option if your pain just started and you haven't had long-term back issues.
IstanbulAges 18–50 - NCT07645859Recruiting
High-Intensity vs. Moderate Exercise for Chronic Lower Back Pain
This trial compares two types of exercise programs—one with short, intense bursts of activity and one with steady, moderate activity—to see which works better for people with long-lasting lower back pain that has no clear medical cause. You would participate in supervised exercise sessions over several weeks.
KarachiAges 20–48 - NCT07241559Recruiting
Low back pain treatment study: injection and mobilization
This study tests two treatments for chronic low back pain: a special injection of dextrose (a sugar solution) guided by ultrasound, and a technique to mobilize the fascia (connective tissue) in the lower back. It aims to see if these help people who haven't found relief from standard treatments.
Ankara, AltındağAges 18–65 - NCT07163117Recruiting
Back exercises for female university students with back pain
This study tests two different types of back exercises to see which works better for reducing mechanical low back pain (pain not caused by injury or disease) in female university students. It may help you find a good exercise routine if you have had this type of back pain for a while.
CairoAges 18–24 - NCT07742111Recruiting
Virtual reality for long-term low back pain
This study tests whether virtual reality exercises can help people with chronic low back pain feel better and move more comfortably. You might join if you have had low back pain for a while, your pain is moderate, and you have some fear of movement.
AmaranteAges 18 years+ - NCT07386548Recruiting
Biologic injection for low back disc problems
This study tests if an injection can help people with a herniated disc in the lower back who have not gotten better with other treatments and are already planning surgery. It aims to see if the injection can reduce symptoms and possibly avoid or improve surgery outcomes.
Manhattan, New YorkAges 18 years+ - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT07724704Recruiting
Exercise comparison for long-term low back pain
This study compares two sets of exercises (called McGill and Sahrmann) to see which is better at reducing chronic low back pain. If you have had non-specific low back pain for more than 12 weeks, this trial may help you strengthen your core and feel better without surgery or medication.
Lahore, Punjab ProvinceAges 20–50 - NCT06661850Recruiting
Using Nociscan to guide discogenic low back pain surgery
This trial tests whether using a tool called Nociscan helps improve outcomes in people having surgery for low back pain caused by damaged discs. It may help doctors decide which discs need treatment.
Beverly Hills, CaliforniaAges 18–70 - NCT07251959Enrolling by invitation
Exercise vs. exercise plus manual therapy for chronic back pain
This study tests whether a workplace exercise program, with or without hands-on manual therapy, can help reduce chronic spinal pain in desk workers. It is designed for UCAM University staff who have had persistent back pain for at least 3 months.
Murcia, MurciaAges 18 years+ - NCT07426562Recruiting
Stretching vs. Dry Needling for Tight Hamstrings in Chronic Back Pain
This trial tests two treatments for tight hamstrings in people with long-lasting low back pain: a special stretch and dry needling (thin needles placed in trigger points). It aims to find which helps reduce tightness and pain.
Peshawar, Khyber PakhtunkhwaAges 20–50 - NCT07474610Recruiting
Belly muscle and arm function in chronic low back pain
This study looks at how a deep belly muscle (transversus abdominis) relates to arm and shoulder function in people with long-term low back pain. It may help understand why some people have trouble with upper body movements.
AnkaraAges 18–45 - NCT07636967Recruiting
Ankle Muscle Strength in Chronic Low Back Pain
This study measures the strength and function of ankle muscles in people with chronic low back pain lasting over 3 months. Understanding how ankle muscles work may help explain why some people develop long-term low back pain.
Tanta, Gharbia GovernorateAges 20–25 - NCT07684118Enrolling by invitation
Egoscue vs core exercises for chronic low back pain
This study compares two types of exercises—Egoscue and core stabilization—to help people with chronic low back pain and an exaggerated lower back curve. The goal is to find which approach better reduces pain and improves function.
Lahore, Punjab ProvinceAges 25–55 - NCT03836248Recruiting
Osteopathic care added to standard treatment for chronic low back pain
This study tests whether adding osteopathic treatment to usual medical care can improve chronic low back pain. It focuses on people whose back pain has no clear structural cause and has lasted more than 3 months.
ToulouseAges 18–64 - NCT04074798Recruiting
Breathing over fast and slow movements for back pain
This study tests how breathing changes (hyperventilation) might affect people with long-lasting low back pain. It may help researchers understand triggers or symptoms, and compare them to people who do not have back pain.
HasseltAges 20–60 - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Phoenix, ArizonaAges 18 years+ - NCT04164225Recruiting
Testing how qigong affects brain activity in chronic low back pain
This study looks at how doing qigong may change brain activity and physical symptoms in adults with long-lasting low back pain. It’s mainly to see whether the brain and symptom measures can be identified and tracked after qigong practice.
Minneapolis, MinnesotaAges 18–70 - NCT04226716Recruiting
Studying pelvic pain causes in multiple or first pregnancies
This study looks at why pelvic girdle pain happens during pregnancy, focusing on body sensing (proprioception), stress factors, and inflammation. You may be able to help researchers understand the causes and who is most at risk.
HasseltAges 18–40
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Common questions
- Are there clinical trials for chronic low back pain?
- Yes. Clin2 currently lists 270 recruiting chronic low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.