Clinical trials
Chronic Low Back Pain clinical trials
Below are recruiting chronic low back pain clinical trials, each written for real people, not researchers. We’re tracking 268 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07190807Recruiting
Optimizing spinal cord stimulation for chronic back and leg pain
This trial tests if a spinal cord stimulator with a new way of adjusting electrical settings (called independent current control) can better manage chronic pain in the back, trunk, or limbs. The goal is to find more effective sequences to reduce pain and improve daily life.
Greenwood, ColoradoAges 18 years+ - NCT07193212Recruiting
Osteopathic treatment for low back pain and leg health
This study tests whether a hands-on osteopathic treatment can improve how your legs and feet work if you have chronic low back pain. It may help you understand if this type of manual therapy is a good option for your pain.
Auburn, AlabamaAges 18–65 - NCT06944730Recruiting
Trunk muscle training for better movement and balance in low back pain
This study tests whether trunk muscle training can improve the quality of your movements and balance if you have chronic low back pain. It is designed for people with moderate pain and no other major health issues.
Hong KongAges 18–55 - NCT07176845Recruiting
Tracking back pain patterns with your smartphone
This study uses your smartphone's motion sensors to track how your back pain changes over time. It might help you understand your pain patterns — and helps researchers learn more about low back pain.
BernAges 18 years+ - NCT07178561Recruiting
Exercise for older adults with chronic back pain and anxiety
This study tests whether a supervised exercise program can reduce disability and improve mental health in older adults with chronic low back pain, poor sleep, and mild to moderate anxiety or depression.
Gaza, Gaza StripAges 55–70 - NCT07173335Recruiting
Healthy lifestyle and pain care for rural residents
This trial tests a program that combines healthy lifestyle coaching with pain management for people living in rural areas who have chronic joint or back pain. It aims to help you feel better and move easier by addressing both pain and habits like diet, exercise, sleep, and smoking.
Coffs Harbour, New South WalesAges 18 years+ - NCT07161661Recruiting
Osteopathic treatment for chronic low back pain in veterans
This trial tests whether adding osteopathic manipulative treatment (OMT) to standard VA care helps reduce chronic low back pain. OMT involves a healthcare provider using their hands to move and stretch muscles and joints.
Hines, IllinoisAges 18 years+ - NCT05100381Recruiting
Dry needling for long-lasting lower back muscle pain
This study tests whether dry needling (thin needles placed into specific muscles) can reduce moderate, long-lasting lower back pain. It focuses on people who have pain from trigger points in a specific back muscle, rather than pain caused by other medical problems.
Tehran, Tehran ProvinceAges 18–45 - NCT07163117Recruiting
Back exercises for female university students with back pain
This study tests two different types of back exercises to see which works better for reducing mechanical low back pain (pain not caused by injury or disease) in female university students. It may help you find a good exercise routine if you have had this type of back pain for a while.
CairoAges 18–24 - NCT07163546Enrolling by invitation
Lifestyle redesign for chronic low back pain
This trial tests a person-centered lifestyle program to help people with chronic low back pain learn new ways to manage daily activities and reduce pain. It may be a good fit if you have had low back pain for at least 3 months and are looking for non-surgical support.
Ankara, AltındağAges 18–65 - NCT07150702Recruiting
Close follow-up for low back pain
This study is testing whether closer follow-up care helps people with long-term low back pain feel better faster. You'll receive a standard physical therapy program but with more frequent check-ins to see if extra support improves your recovery.
Istanbul, FatihAges 18–65 - NCT05832918Recruiting
Core exercises plus brain tasks for chronic low back pain
This study tests whether doing core (stability) exercises along with simple cognitive (thinking) tasks can reduce long-lasting low back pain. It may help if your pain has lasted at least 3 months and you can safely take part in exercise.
Tehran, Iran (the Islamic Republic Of)Ages 18–55 - NCT07141082Recruiting
Art therapy for older adults with long-term back pain
This study tests whether expressive art therapy (like drawing, painting, or music) can help older adults manage chronic low back pain. It aims to reduce pain and improve quality of life without medication.
Hong KongAges 60 years+ - NCT07141069Recruiting
Art therapy for adults with chronic low back pain
This study tests whether making art (art therapy) can help adults with ongoing low back pain feel better. You would take part in art sessions to see if this approach reduces pain and improves your quality of life.
Hong Kong, Hong KongAges 18–59 - NCT07134699Recruiting
Back pain's effect on thinking in older adults
This study looks at how long-term lower back pain affects thinking skills like memory and attention in adults aged 60 to 85. Participants must speak Cantonese, be right-handed, and have normal thinking abilities. The study uses email or text for some tasks.
Hong KongAges 60–85 - NCT07127380Recruiting
Comparing two types of spine surgery for disc-related low back pain
This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.
Lodz, Łódź VoivodeshipAges 18 years+ - NCT07133139Recruiting
Dry needling for chronic low back pain
This study tests whether a treatment called dry needling (using thin needles on muscle knots) helps people with long-term low back pain tied to muscle tightness. It is for those who have not tried this treatment before and whose main pain is in the lower back.
Pittsburgh, PennsylvaniaAges 20–70 - NCT07132762Recruiting
Shock wave therapy for chronic low back pain
This study tests whether adding a special sound wave therapy (called ESWT) to standard care (like exercise and education) can reduce pain and improve daily function in people with long-term low back pain. It is designed for people whose back pain does not have a specific known cause.
DenizliAges 18–65 - NCT07122453RecruitingPhase 1
Study of CNTX-3001 for severe chronic low back pain
This trial tests a medicine called CNTX-3001, given as a spinal injection, for people with long-term, severe low back pain that hasn't improved with other treatments.
Napa, CaliforniaAges 18–75 - NCT07125027Recruiting
Exercise and mindfulness for sciatica pain
This study tests a program called Move-MORE that combines exercise and mindfulness to help people with nerve-related leg pain (sciatica) that has lasted at least 3 months. You would use the program at home, attend weekly video sessions for 8 weeks, and complete questionnaires and daily surveys to see if the program improves your pain and quality of life.
Portland, OregonAges 18–75 - NCT07111286Recruiting
Imagining movements to help chronic low back pain
This trial tests whether imagining movements (motor imagery) can help improve daily function and reduce pain in people with chronic low back pain. You will participate in a rehabilitation program, and if you are in the motor imagery group, you will also practice mentally rehearsing specific movements.
DijonAges 18 years+ - NCT07112404Recruiting
Dry Needling for Low Back Pain Study
This study tests a type of dry needling (inserting thin needles into muscles) to see if it helps people with and without chronic low back pain. You may join if you have no recent low back pain or if you have had low back pain for at least 3 months, as long as you have not had major back surgery or certain treatments.
Galveston, TexasAges 18–65 - NCT07058376Enrolling by invitation
Herbal medicine for chronic low back pain
This trial tests whether a herbal medicine strategy can safely and effectively reduce chronic low back pain lasting over 3 months. It may be an option if your pain has been moderate to severe and you are looking for alternative treatments.
Seoul, Gangnam-GuAges 19–69 - NCT07051772Recruiting
Predicting success in back pain rehab
This study looks for factors that help people with long-term low back pain succeed in rehabilitation programs. Researchers will track participants during their rehab to learn what works best.
Clermont-Ferrand, AuvergneAges 18–65
Hear when a new Chronic Low Back Pain trial opens
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Common questions
- Are there clinical trials for chronic low back pain?
- Yes. Clin2 currently lists 268 recruiting chronic low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.