Clinical trials
Chronic Non-specific Low Back Pain clinical trials
Below are recruiting chronic non-specific low back pain clinical trials, each written for real people, not researchers. We’re tracking 61 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03836248Recruiting
Osteopathic care added to standard treatment for chronic low back pain
This study tests whether adding osteopathic treatment to usual medical care can improve chronic low back pain. It focuses on people whose back pain has no clear structural cause and has lasted more than 3 months.
ToulouseAges 18–64 - NCT04631133Recruiting
Study of outcomes after surgery using the LISA implant
This study follows adults who get back surgery using the LISA implant to see how well they do afterward and how outcomes change over time. It focuses on people whose long-term, non-surgical care did not relieve low-back pain from specific age-related disc changes.
SilkeborgAges 18 years+ - NCT05422040Recruiting
Dry needling or tecartherapy for long-term low back pain
This study compares two physical therapies—dry needling versus tecartherapy—to see which helps people with long-lasting, non-specific low back pain. You may be eligible if your pain has lasted more than 6 weeks and is not caused by nerve or serious underlying conditions.
Alcalá de Henares, MadridAges 18–65 - NCT05706103Recruiting
Exercise therapy for recurrent low back pain with brain changes
This trial studies whether a specific exercise program can improve recurrent low back pain by changing activity in muscles and the brain. If you have non-specific low back pain that comes and goes over time, you may be asked to do exercises and undergo brain and muscle testing (including MRI).
Ghent, Oost-VlaanderenAges 18–45 - NCT05832918Recruiting
Core exercises plus brain tasks for chronic low back pain
This study tests whether doing core (stability) exercises along with simple cognitive (thinking) tasks can reduce long-lasting low back pain. It may help if your pain has lasted at least 3 months and you can safely take part in exercise.
Tehran, Iran (the Islamic Republic Of)Ages 18–55 - NCT05851196Recruiting
Personalized exercise for recurrent low back pain
This study looks at how back muscle features can help tailor an exercise program for people with recurring, non-specific low back pain. It may help by matching exercises to your specific back function and symptoms.
DiepenbeekAges 18–60 - NCT05909709RecruitingPhase 1
Tested injections for chronic facet-related back pain
This Phase 1 study tests the safety of an injection called Alocyte in adults with long-lasting back pain coming from the facet joints. If you qualify, you may be followed closely to check side effects and how you respond over multiple visits.
North Miami, FloridaAges 18 years+ - NCT05991440Recruiting
Race and income differences in chronic low back pain study
This study looks at how race and income affect chronic low back pain. Researchers want to understand differences in pain and daily function between Black and White adults with long-lasting back pain.
St Louis, MissouriAges 18–85 - NCT06271447Recruiting
Pain questionnaire study for chronic low back pain
This study looks at how well pain questionnaires measure changes in chronic low back pain over time. If you have had long-term low back pain, researchers want to see if these surveys can accurately detect meaningful improvements.
Istanbul, None SelectedAges 18–65 - NCT06310096Recruiting
Stretching for chronic low back pain
This study tests whether a special stretching technique for the connective tissue in your lower back can help reduce pain and improve function in people with chronic low back pain (pain lasting 3 months or more). You would attend physiotherapy sessions and do regular stretches.
AnkaraAges 20–60 - NCT06452030Recruiting
Testing a new exercise for trunk muscles in low back pain
This study is testing a special training program for the muscles that support your spine. It is for people who have had frequent but mild episodes of low back pain that have recently calmed down. The goal is to see if changing how these muscles work can prevent future pain.
GhentAges 18–65 - NCT06566144Recruiting
Adding osteopathy to standard care for chronic low back pain
This study tests whether adding osteopathy (a type of hands-on therapy) to standard care helps people with long-term low back pain feel better and move more easily. It is for adults with chronic, nonspecific back pain that has lasted at least 6 weeks.
São PauloAges 18–70 - NCT06679205Recruiting
Multidisciplinary care for long-term low back pain
This study tests a team-based, non-drug treatment program for long-term low back pain. It combines physical therapy, education, and support to help reduce pain and improve daily function.
Barcelona, BarcelonaAges 18 years+ - NCT06696300Recruiting
Breathing muscle training for chronic low back pain
This study tests whether training the muscles you use to breathe can help reduce chronic low back pain. You will practice specific breathing exercises and see if they improve your pain and function.
Kırşehir, CenterAges 18–65 - NCT06704425Recruiting
How back pain affects thinking in older adults
This study looks at how chronic low back pain might affect memory, attention, and other thinking skills in adults aged 60 to 85. You will complete questionnaires, thinking tasks, and a brain scan to help researchers understand the link between pain and cognitive function.
Hong Kong, Hong KongAges 60–85 - NCT06856642Recruiting
Comparing belly drawing exercises with ultrasound for chronic back pain
This study compares two types of physical therapy for chronic low back pain: one uses real-time ultrasound to help you learn a special belly-drawing maneuver, the other is standard physical therapy. The goal is to see which method reduces pain better.
BoluAges 18–65 - NCT06928597Recruiting
GPR therapy for chronic low back pain
This study tests a physical therapy method called Global Postural Re-education (GPR) for people with long-term low back pain that is not caused by a specific disease. It aims to see if GPR can help reduce pain and improve function.
Salvador, Estado de BahiaAges 18–55 - NCT06963658Recruiting
Isometric Exercise and Pain Sensitivity in Chronic Low Back Pain
This study tests whether a simple, still (isometric) exercise can reduce how sensitive you are to pain. It is for adults with long-term low back pain who can safely do physical therapy exercises.
Bisha, 'Asir RegionAges 18 years+ - NCT06973837Recruiting
Brain study on chronic back pain and insomnia
This study looks at how the brain works in people with chronic low back pain and/or chronic insomnia. It compares these groups to healthy volunteers using MRI and pain tests.
LeuvenAges 18–60 - NCT06984354Recruiting
Digital treatments for chronic low back pain
This trial tests a smartphone app to help people with long-term low back pain. It aims to see if digital treatments can reduce pain and improve daily function.
Randwick, New South WalesAges 18 years+ - NCT06999772Recruiting
Combining brain stimulation with physiotherapy for chronic back pain
This study tests if adding a non-invasive brain stimulation technique to physiotherapy can help veterans with chronic low back pain. It aims to improve pain and function by targeting both the brain and the body.
Québec, QuebecAges 18–65 - NCT07026097Recruiting
Online vs. supervised Pilates for low back pain
This study compares doing Pilates exercises online with doing them in-person under supervision. It's for people with ongoing low back pain to see which method is more effective for reducing pain and improving function.
Lahore, Punjab ProvinceAges 18–45 - NCT07134699Recruiting
Back pain's effect on thinking in older adults
This study looks at how long-term lower back pain affects thinking skills like memory and attention in adults aged 60 to 85. Participants must speak Cantonese, be right-handed, and have normal thinking abilities. The study uses email or text for some tasks.
Hong KongAges 60–85 - NCT07141069Recruiting
Art therapy for adults with chronic low back pain
This study tests whether making art (art therapy) can help adults with ongoing low back pain feel better. You would take part in art sessions to see if this approach reduces pain and improves your quality of life.
Hong Kong, Hong KongAges 18–59
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Common questions
- Are there clinical trials for chronic non-specific low back pain?
- Yes. Clin2 currently lists 61 recruiting chronic non-specific low back pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic non-specific low back pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic non-specific low back pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.