Clinical trials
Chronic Pain Management clinical trials
Below are recruiting chronic pain management clinical trials, each written for real people, not researchers. We’re tracking 219 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06999772Recruiting
Combining brain stimulation with physiotherapy for chronic back pain
This study tests if adding a non-invasive brain stimulation technique to physiotherapy can help veterans with chronic low back pain. It aims to improve pain and function by targeting both the brain and the body.
Québec, QuebecAges 18–65 - NCT06984354Recruiting
Digital treatments for chronic low back pain
This trial tests a smartphone app to help people with long-term low back pain. It aims to see if digital treatments can reduce pain and improve daily function.
Randwick, New South WalesAges 18 years+ - NCT06969456Recruiting
Exercise and nerve stimulation for chronic back pain
This study looks at whether combining exercise with a type of nerve stimulation (called neuromodulation) can help people with long-term spinal pain that has nerve involvement. It may be an option if you have had pain for at least 6 months and it is severe.
Valencia, ValenciaAges 18–70 - NCT06940986Recruiting
Holistic pain self-management for military health system patients
This trial tests a holistic pain self-management program for people with long-term muscle or bone pain. It aims to help you take control of your pain through education and support, without relying only on medications.
Fairbanks, AlaskaAges 18 years+ - NCT06932887RecruitingPhase 3
Walking to reduce arthritis pain
This study tests a walking program to help reduce pain from osteoarthritis. It is designed for people with arthritis in their hips, knees, feet, or spine.
Salt Lake City, UtahAges 45 years+ - NCT06878014RecruitingPhase 4
Morphine for pain relief after hip replacement surgery
This trial tests different doses of morphine given during spinal anesthesia to find the safest and most effective way to control pain after hip replacement surgery. If you are having a total hip replacement, you may be able to join.
Sosnowiec, Silesian VoivodeshipAges 18–75 - NCT06856733Recruiting
Better opioid management for long-term non-cancer pain
This study tests a new way to help people who have been taking opioids for chronic pain (not caused by cancer) for at least 90 days. The goal is to improve treatment and reduce risks, such as developing tolerance or side effects, while still managing pain effectively.
Gävle, Gävleborg CountyAges 18–70 - NCT06795243Recruiting
Physical therapy for endometriosis and exercise adherence
This study tests whether physical therapy (exercise for your muscles) can help with endometriosis symptoms and how well people stick with the program. If you have endometriosis and can do light strength exercises, you may be able to join.
SevilleAges 18 years+ - NCT06381063RecruitingPhase 3
Anti-inflammatory for heart surgery
This trial is testing whether a non-steroidal anti-inflammatory drug (NSAID) given during heart surgery can reduce complications. It's for people having planned open-heart surgery with a heart-lung machine.
AmiensAges 18 years+ - NCT06052384Recruiting
Better sleep care for chronic pain patients
This study tests whether adding a sleep specialist to your pain care team can help you feel better. If you have chronic pain (lasting over 3 months) and are now seeing a pain doctor for the first time, you may be able to join.
Le Puy-en-VelayAges 18 years+ - NCT06632535Recruiting
Group visits and chiropractic care for older adults with chronic spine pain
This study tests whether group medical visits combined with chiropractic care can help older adults with chronic neck or back pain. If you join, you'll receive chiropractic treatments and attend group visits to learn pain management strategies.
Boston, MassachusettsAges 65 years+ - NCT06617494Recruiting
Study of pain control in chronic jaw pain
This study looks at how well the body's natural pain control system works in people with long-term jaw pain (TMD). It compares people with and without jaw pain to better understand why some have trouble turning off pain signals.
Minneapolis, MinnesotaAges 18–74 - NCT06471075Recruiting
Mindfulness for Pain Before Orthopedic Procedure
This study tests whether a short mindfulness (calm focus) exercise before an in-clinic orthopedic procedure can help reduce pain. If you are getting kyphoplasty or radiofrequency ablation at Tallahassee Orthopedic Center, this brief program might make your experience more comfortable.
Tallahassee, FloridaAges 18 years+ - NCT06407115Enrolling by invitation
Pain care support for rural patients
This study tests a nurse-led program to help people living in rural areas manage chronic pain. You'll work with a care manager who can support your pain treatment goals.
Winston-Salem, North CarolinaAges 18 years+ - NCT06386224Recruiting
Online pain self-management for pancreatitis pain
This study tests an online pain-management program for adults with chronic or recurrent acute pancreatitis. The program is done on your own device (or a loaner iPad) and is designed to help you learn skills to cope with pain and improve daily life.
Seattle, WashingtonAges 18 years+ - NCT06387290RecruitingPhase 3
Mindfulness and pain management for chronic pain on opioids
This study tests whether adding mindfulness training to standard pain management visits can help people with chronic pain who are taking long-term opioids. It aims to improve pain relief and reduce opioid-related risks.
La Jolla, CaliforniaAges 18 years+ - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT06350786Recruiting
Using a placebo to help reduce opioid pain medication
This trial tests whether a special placebo pill, given with your knowledge, can help you reduce your opioid pain medication. You'll work with your own doctor to safely lower your dose while taking the placebo.
Zurich, Canton of ZurichAges 18 years+ - NCT06351046Recruiting
Preventing chronic pain from getting worse
This trial tests a virtual reality program to see if it can help prevent long-term pain from becoming more severe. You may be eligible if you have had pain for at least 3 months and rate your average pain as moderate or higher.
Copenhagen, København Ø.Ages 18 years+ - NCT06038240Recruiting
Pain self-management program for knee replacement
This study is testing a program to help people manage pain on their own before and after total knee replacement surgery. It aims to improve recovery and reduce reliance on pain medications.
Charlottesville, VirginiaAges 18–85 - NCT06001749RecruitingPhase 2
Psilocybin for cancer pain study
This trial tests whether psilocybin (a psychedelic drug) can help with severe cancer pain. You may qualify if your pain is high despite strong medications and you are willing to be monitored closely.
Boston, MassachusettsAges 18 years+ - NCT05689944Recruiting
Dance therapy for teens with chronic pain
This trial studies whether dance therapy can help reduce chronic pain in teens when usual pain treatments haven’t worked well. It may be helpful if you’re followed in a pain clinic and are able to participate in movement-based sessions.
BronAges 12–20 - NCT05477004Enrolling by invitation
Study of ketamine infusions for ongoing chronic pain
This study is observing people with chronic pain who are getting ketamine infusions at Stanford. You may help by completing email surveys about how you feel, which can help the team understand the treatment’s impact.
Stanford, CaliforniaAges 18 years+ - NCT05404581Recruiting
Insula brain stimulation for long-term nerve pain
This trial tests whether stimulating a specific brain area (the insula) can reduce chronic nerve pain. It is for people whose pain has lasted at least 6 months and has not improved enough with several pain medicines and other procedures.
Charlottesville, VirginiaAges 18–80
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Common questions
- Are there clinical trials for chronic pain management?
- Yes. Clin2 currently lists 219 recruiting chronic pain management studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic pain management trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic pain management trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.