Clinical trials · San Francisco, CA
Chronic pain clinical trials in San Francisco
We’re tracking 27 recruiting chronic pain studies with a site in or near San Francisco — including Phase 1, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near San Francisco
- NCT05265000Recruiting
Skin electrical stimulation for chronic low back pain
This study tests whether a gentle electrical treatment placed on the skin near the spine can reduce chronic low back pain. If you qualify, you’ll try the stimulation and complete several assessments over a day, so the team can measure any pain and function changes.
San Francisco, CaliforniaAges 21–85 - NCT06183281Recruiting
Comparing two non-drug approaches for chronic pain
This study compares two different ways to help people manage chronic pain without using medications. Over 12 months, you'll use a smartphone app and learn strategies to feel better and have more control over your pain.
San Francisco, CaliforniaAges 18 years+ - NCT06919640Enrolling by invitationPhase 1
Psilocybin and brain implant study
This trial tests whether psilocybin (the active ingredient in magic mushrooms) affects brain activity in people who already have a brain-sensing device implanted. It may help researchers understand how psilocybin works in the brain.
San Francisco, CaliforniaAges 21–75 - NCT07119645Recruiting
Collagen supplement for knee discomfort relief
This trial tests whether a daily collagen supplement (NT-II™) can reduce knee discomfort during activities like walking or climbing stairs. You may qualify if you have mild to moderate knee pain during exercise, no arthritis, and are generally healthy.
San Francisco, CaliforniaAges 20–65 - NCT06778070Recruiting
Pelvic pain study testing yoga therapy for relief
This trial tests whether yoga therapy can help reduce chronic pelvic pain in women and non-binary individuals over 6 months. You'll join online yoga classes and see if they improve your pain and daily life.
San Francisco, CaliforniaAges 18 years+ - NCT06354699Recruiting
Pain after surgery in children: a long-term study
This study looks at children who have certain types of surgery to understand who might have ongoing pain, what causes it, and how it affects them over time.
San Francisco, CaliforniaAges Up to 16 years - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT05963607Recruiting
Weighted blanket trial to reduce chronic pain
This study tests whether using a 15-pound weighted blanket can lower pain and improve sleep for Veterans with long-lasting, non-cancer musculoskeletal pain. It may help by reducing discomfort during rest and sleep.
San Francisco, CaliforniaAges 18 years+ - NCT06327542Recruiting
Group pain management in primary care clinics
This trial tests a group-based program to help people with chronic pain manage their symptoms. It is offered in primary care clinics that serve underinsured communities, and sessions are available in English or Spanish.
San Francisco, CaliforniaAges 18 years+ - NCT06827262Recruiting
A procedure for vertebrogenic back pain relief
This trial tests a minimally invasive procedure that uses a special device to target and treat nerve-related back pain coming from the vertebrae (the bones in your spine). It may offer lasting relief without more major surgery.
Larkspur, CaliforniaAges 18 years+ - NCT03876054Recruiting
Tracking outcomes after Abbott neurostimulator implantation
This study follows people long-term after they get an Abbott device implanted to help with chronic pain. It aims to learn how well the therapy works in real-world care over time.
Larkspur, CaliforniaAges 18 years+ - NCT01550575Recruiting
Study of outcomes in people treated with Boston Scientific devices
This study looks back at what happened to patients after treatment (or if they could have used) Boston Scientific medical devices. It may help improve how these devices are used and understand real-world results.
Larkspur, CaliforniaAges 18 years+ - NCT06559735Recruiting
Brain oxygen measurement in chronic pain with spinal cord stimulation
This trial tests a new device to measure oxygen levels in the brain of people with chronic pain who are receiving spinal cord stimulation. It aims to see if brain oxygen changes can help manage pain better.
Walnut Creek, CaliforniaAges 18 years+ - NCT05657964Recruiting
Study of a back pain exercise program for chronic low back pain
This trial tests whether a structured exercise/education program can help people with chronic lower back pain. You may qualify if your pain and disability scores are high enough and you can complete study activities in English.
Redwood City, CaliforniaAges 18–65 - NCT04441034RecruitingPhase 4
Compare two medicines for long-term pain in real life
This trial compares two types of medicines—anti-convulsants and anti-depressants—for people with persistent pain lasting more than 3 months. It aims to find out which option works better in everyday care and for which patients.
Redwood City, CaliforniaAges 18 years+ - NCT06377969Recruiting
Spinal cord stimulation for chronic pelvic pain
This study tests a device called a spinal cord stimulator — a small implant that sends mild electrical pulses to nerves in your spine — to see if it can reduce long-term pelvic pain that hasn't gotten better with other treatments.
Redwood City, CaliforniaAges 18 years+ - NCT04546685Recruiting
Spanish online group program to help manage long-term pain
This trial tests a one-time, Spanish-language online group program (“Empowered Relief”) for people with long-term pain. It may help you learn coping skills and strategies to reduce the impact of chronic pain.
Palo Alto, CaliforniaAges 18 years+ - NCT06025201Recruiting
Brain activity markers for chronic low back pain
This study uses a safe, non-invasive cap with sensors (EEG) to measure your brain activity and look for patterns linked to chronic low back pain. It aims to better understand pain so doctors can improve treatments.
Palo Alto, CaliforniaAges 18–80 - NCT06741579RecruitingPhase 3
Pain relief study for nerve injury pain
This trial tests how well two types of peripheral nerve stimulation (PNS) devices relieve chronic pain caused by a single nerve injury. It looks for people who already have a referral for PNS therapy as part of their usual care and who have gotten at least 50% relief from a diagnostic nerve block.
Palo Alto, CaliforniaAges 18 years+ - NCT04142177Recruiting
Test which pain treatments work best for chronic low back pain
This study compares how well different pain treatments reduce low back pain and improve daily life. You may be asked to start or continue care through the VA and attend in-person sessions while completing pain and activity questionnaires.
Palo Alto, CaliforniaAges 18 years+ - NCT07425691Recruiting
A program for teens with chronic pain and their parents
This study offers a program to help teens with chronic pain learn skills to manage their pain and improve daily life. The program includes both the teen and a parent, so it's a team effort.
Palo Alto, CaliforniaAges 10–17 - NCT06704061Recruiting
Online yoga vs ACT for chronic pain in veterans
This study compares online yoga with Acceptance and Commitment Therapy (ACT), a type of talk therapy, to see which helps veterans better manage long-lasting muscle or bone pain. You can join from home through the internet.
Palo Alto, CaliforniaAges 18 years+ - NCT05700682Recruiting
MRI-guided artery blockage procedure for long-term joint pain
This study tests whether an MRI scan that looks at blood flow can help target a joint embolization procedure to reduce chronic shoulder, hip, or knee pain. It first uses MRI to find signs of increased blood flow, then may use the findings to guide treatment if you qualify.
Palo Alto, CaliforniaAges 25–80 - NCT07090018Enrolling by invitation
A single session to help manage pain after C-section
This trial tests a one-time class (called Empowered Relief) for women who still have pain 6 weeks after a cesarean delivery. The goal is to see if this session helps reduce ongoing pain and improve recovery.
Palo Alto, CaliforniaAges 18 years+
Hear when a new Chronic pain trial opens near San Francisco, CA
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Chronic pain trials in other cities
Where these studies are running near San Francisco
Institutions with a site for the recruiting chronic pain studies listed above.
- Stanford University · 5 studies
- University of California, San Francisco · 4 studies
- Boomerang Healthcare · 2 studies
- California Orthopedics & Spine · 2 studies
- MarinHealth Spine Institute · 2 studies
- San Francisco VA Medical Center · 2 studies
- VA Palo Alto Health Care System · 2 studies
- 1070 Arastradero Rd
What taking part in a chronic pain study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting chronic pain studies in California.
Common questions
- Are there chronic pain clinical trials near San Francisco?
- Yes. We're currently tracking 27 recruiting chronic pain studies with a site near San Francisco, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a chronic pain study near San Francisco?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in San Francisco to take part?
- Not necessarily. These studies have a site near San Francisco, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a chronic pain trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New chronic pain studies open near San Francisco regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.