Clinical trials
Chronic Renal Disease clinical trials
Below are recruiting chronic renal disease clinical trials, each written for real people, not researchers. We’re tracking 342 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07194590RecruitingPhase 2
Equol and blood vessel health in women with kidney disease
This trial tests whether a supplement called equol, made from soy, can improve blood vessel function in postmenopausal women with moderate to advanced chronic kidney disease. Participants take equol or a placebo for several weeks to see if it helps their heart health.
Aurora, ColoradoAges 50 years+ - NCT01752738Recruiting
Study of gut microbial metabolites in chronic kidney disease
This trial studies how substances made by gut microbes travel in people with chronic kidney disease. You may be asked to have a planned colonoscopy so researchers can measure intestinal samples and better understand kidney disease.
Leuven, Vlaams BrabantAges 18–85 - NCT07405216RecruitingPhase 4
SGLT2 inhibitors for teens with early kidney disease
This trial tests whether a type of medicine called SGLT2 inhibitors can help teenagers with early-stage chronic kidney disease. It looks at how safe and effective these drugs are for slowing down kidney damage.
Aguascalientes, AguascalientesAges 14–18 - NCT07113743Enrolling by invitationPhase 1/Phase 2
Gene therapy for X-linked chronic granulomatous disease
This trial tests a new gene therapy for X-linked chronic granulomatous disease (CGD), a condition that causes severe infections. The treatment uses your own stem cells that are modified to fight the disease, aiming to reduce infections and inflammation.
Bethesda, MarylandAges 3–60 - NCT04185844Recruiting
Chronic kidney health study for Native American adults
This study follows Native American adults with kidney function changes (either moderately reduced kidney filtration or early urine protein). It aims to better understand kidney disease over time and what factors predict progress, which may help improve care for people like you.
Phoenix, ArizonaAges 21–80 - NCT05189925RecruitingPhase 1
Correcting a missing immune enzyme using an mRNA cell therapy
This early-phase trial tests whether an mRNA-based treatment can correct a key immune problem in people with chronic granulomatous disease (CGD). It may help your immune cells work better against infections, but this is mainly to check safety and early signs of benefit.
Bethesda, MarylandAges 18–75 - NCT06867471Recruiting
Ketone drink study for kidney disease patients
This study tests if a ketone supplement can reduce protein in urine and protect kidney function in people with chronic kidney disease or polycystic kidney disease. You drink a special supplement and researchers measure how it affects your kidneys.
Herning, JutlandAges 18 years+ - NCT06676527Recruiting
Vorolanib for advanced kidney cancer after first treatment
This trial tests a targeted therapy pill, vorolanib, for people with advanced kidney cancer that has clear cell features and has gotten worse after initial treatment. It may offer a new option when standard second-line treatments are not working.
Nanjing, JiangsuAges 18–80 - NCT07115953Recruiting
Spiral nerve treatment for uncontrolled high blood pressure
This trial tests a new procedure to treat high blood pressure by using a special catheter to calm overactive nerves in your kidneys. It may help you achieve better blood pressure control if medications are not enough.
MelbourneAges 18 years+ - NCT07136792Recruiting
New injection for anemia in dialysis patients taking roxadustat
This study tests a new once-monthly injection called pegmolesatide for anemia in people with kidney disease on dialysis who are already taking roxadustat. It aims to see if switching to this injection can keep hemoglobin levels stable and reduce the need for transfusions.
Beijing, Beijing MunicipalityAges 18–75 - NCT04404114Recruiting
Shear wave ultrasound to tell acute from chronic kidney disease
This study checks whether a special ultrasound can help tell whether kidney problems started suddenly (acute) or have been present longer (chronic). It may help doctors choose the right next steps faster in the emergency room.
TaipeiAges 20 years+ - NCT06551311Recruiting
Cycling exercise for chronic kidney disease
This study tests whether a special type of cycling exercise (eccentric cycling) is safe and helpful for people with moderate to severe chronic kidney disease (CKD) or who are on dialysis. The goal is to improve fitness and overall health.
Tainan, TaiwanAges 55–85 - NCT06721143RecruitingPhase 1/Phase 2
Study of AION-301 for chronic kidney disease
This trial tests an experimental drug called AION-301 for people with chronic kidney disease (CKD). The goal is to see if it's safe and may help slow kidney decline. It's given by IV infusion and compared to a placebo (inactive infusion).
Miami, FloridaAges 35–75 - NCT02808572Recruiting
Blood and urine tests to study heart risk in kidney disease
This study looks for new markers in blood or urine that may help explain heart (cardiovascular) risk in people with chronic kidney disease. It may help doctors better predict risk, especially in those not yet on dialysis.
MontpellierAges 18–95 - NCT05374291Enrolling by invitationPhase 3
Dapagliflozin trial for kidney and heart outcomes in severe CKD
This study tests whether dapagliflozin can improve kidney and heart-related outcomes in people with severe chronic kidney disease (CKD). You would take the study medicine (or a comparison treatment) and be followed to see how your kidneys and heart do over time.
Canberra, Australian Capital TeritoryAges 18 years+ - NCT05726526Recruiting
Phone app monitoring to help people with advanced kidney disease
This study tests a phone app (with check-ins on things like blood pressure and weight) to help prevent complications in people with advanced chronic kidney disease. You may be a good match if you’re high risk and can actively measure and share your health data with a kidney care team.
Winnipeg, ManitobaAges 18 years+ - NCT07123909Recruiting
Immune adsorbent therapy for dialysis patients with inflammation
This study tests a therapy that absorbs inflammatory substances from the blood during dialysis. It may help people on dialysis who have ongoing inflammation, shown by high IL-6 or CRP levels.
MoscowAges 18 years+ - NCT05196035RecruitingPhase 3
Finerenone plus blood-pressure medicine for kids with kidney disease
This Phase 3 study tests whether finerenone works and is safe in children with chronic kidney disease and significant protein in the urine, when taken with an ACE inhibitor or ARB. It also studies how the medicine moves through the body and its effects over time.
Phoenix, ArizonaAges 6 months–17 years - NCT05457283RecruitingPhase 3
Finerenone safety study for children with kidney disease
This trial studies how safely finerenone works over 18 months in children and young adults with chronic kidney disease who also take an ACE inhibitor or ARB. It aims to better understand long-term side effects when used together with standard kidney blood-pressure medicines.
Phoenix, ArizonaAges 1–18 - NCT06155604RecruitingPhase 2
SGLT2 inhibitor for lupus nephritis with kidney disease
This study tests if an SGLT2 inhibitor can help protect kidney function in people who have lupus nephritis (kidney inflammation caused by lupus) and chronic kidney disease (CKD). The goal is to see if this medicine can slow down further kidney damage.
Hong KongAges 18 years+ - NCT06741072RecruitingPhase 1
Vaccine to prevent EBV-related cancer in transplant patients
This trial tests a vaccine (OSU-2131) that may help prevent cancers caused by the Epstein-Barr virus in people waiting for an organ transplant. The vaccine is designed to train your immune system to fight the virus.
Columbus, OhioAges 18–65 - NCT07082738RecruitingPhase 2
Study of AZD6793 for people with moderate to very severe COPD
This trial tests a new drug called AZD6793 for people with moderate to very severe COPD. It aims to see if the drug can help improve breathing and reduce flare-ups.
Birmingham, AlabamaAges 40 years+ - NCT05249634RecruitingPhase 2
Testosterone treatment study for men with chronic kidney disease
This Phase 2 study tests whether testosterone therapy can help men with chronic kidney disease who have low testosterone and related symptoms. It looks to see if treatment is safe and beneficial, while carefully checking heart, blood, prostate, and clotting risks.
St Louis, MissouriAges 18–85 - NCT07312981Recruiting
Diet tracking study for advanced kidney disease
This study compares different ways to record what you eat and drink for people with advanced kidney disease. It may help find easier methods for dietary tracking.
Herlev, Capital RegionAges 18 years+
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Common questions
- Are there clinical trials for chronic renal disease?
- Yes. Clin2 currently lists 342 recruiting chronic renal disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic renal disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic renal disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.