Clinical trials
Chronic Spinal Pain clinical trials
Below are recruiting chronic spinal pain clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04687215Recruiting
Spinal cord stimulation for painful diabetic nerve pain
This trial studies whether a spinal cord stimulator can reduce pain from diabetic nerve damage in the legs. It focuses on people with long-lasting type 2 diabetes and significant, treatment-resistant pain.
Chicago, IllinoisAges 18 years+ - NCT07040605Recruiting
Neck exercises for chronic pain
This study tests a special set of exercises for your neck muscles to help with chronic neck pain. It focuses on strengthening deep muscles and improving how your body senses neck movement.
Cairo, Giza GovernorateAges 20–40 - NCT07650526Recruiting
Brain Stimulation for Nerve Pain Relief
This study tests two types of magnetic brain stimulation (aiTBS and rTMS) to treat long-lasting nerve pain. Researchers want to see which approach works better and develop a way to predict who will benefit most.
Boulogne-Billancourt, Île-de-France RegionAges 18–80 - NCT03877653Recruiting
Freedom-1 treatment for long-term knee pain in adults
This study tests a procedure called Freedom-1 to reduce long-term, limiting knee pain from knee arthritis. It may help if other non-surgical options didn’t work and you meet specific knee and health requirements.
Placentia, CaliforniaAges 18 years+ - NCT04921592Recruiting
Arm therapy for people with chronic cervical spinal cord injury
This trial looks at an upper-arm exercise program for people with long-term (at least 6 months) spinal cord injuries in the neck area. It may help improve how you use your arms and manage stiffness, while also checking if the program is safe for participants.
West Orange, New JerseyAges 18 years+ - NCT07166952Recruiting
Nerve Stimulation for Chronic Sacroiliac Joint Pain
This study tests whether the SPRINT system, a device that uses mild electrical pulses to block pain signals from the sacroiliac joint, can help people with chronic pain in that area. It aims to see if this treatment works well for those who have not improved with other therapies.
Charleston, South CarolinaAges 18 years+ - NCT06054802Enrolling by invitation
Sleep and pain after spine surgery in teens
This study looks at how sleep quality before and after spine surgery affects pain recovery. It uses text messages to check in with participants, so a mobile device is needed.
Columbus, OhioAges 10–18 - NCT05989230Recruiting
Emotional awareness therapy for pain after orthopedic injury
This trial tests a therapy that helps people understand and express their emotions to manage long-term pain after a serious bone injury. It may help if you have had pain most days for at least three months following surgery for an orthopedic injury.
Baltimore, MarylandAges 18 years+ - NCT06796881Recruiting
Comparison of two therapies for long-term low back pain
This study compares two hands-on treatments for people with chronic low back pain. One uses special tools to massage tight muscles, while the other uses gentle pressure on muscle knots. Both aim to help you move better and feel less pain.
CairoAges 25–45 - NCT06544525Recruiting
Pain test to predict physical therapy results for back pain
This trial tests whether a simple pain test can predict how much you will improve with physical therapy for chronic low back pain. It looks at how your body naturally handles pain, which may help tailor your treatment.
Fort Sam Houston, TexasAges 18–64 - NCT05508360Recruiting
Testing an artificial spacer implant for one-level low back pain
This study tests whether inserting a small artificial implant into a single painful disc can reduce long-term low back pain and disability. It’s for people who tried non-surgical treatments for at least 6 months but still have significant symptoms from degenerative disc disease.
Medellín, AntioquiaAges 22 years+ - NCT07016581Enrolling by invitation
Best length for a spinal cord stimulation test
This study is testing how long a spinal cord stimulation trial should last to best diagnose whether it will help your chronic pain. It compares different trial lengths to see which one gives the most accurate result.
Baltimore, MarylandAges 18 years+ - NCT05684692RecruitingPhase 2
Pain-relief study for adults with schwannomatosis
This Phase 2 study tests whether an antibody medicine (either siltuximab or erenumab) can reduce moderate-to-severe pain in adults with schwannomatosis. It compares the medicine to a placebo and looks for improved pain control and tolerability.
Boston, MassachusettsAges 18 years+ - NCT04039633Recruiting
Spinal cord stimulation study for chronic erythromelalgia pain
This trial tests whether spinal cord stimulation (a device that sends mild electrical signals to the spinal cord) can reduce chronic pain from erythromelalgia when medicines have not helped. You may need to try stimulation for two weeks first, and you will likely feel tingling during that test.
HaldenAges 18 years+ - NCT07426562Recruiting
Stretching vs. Dry Needling for Tight Hamstrings in Chronic Back Pain
This trial tests two treatments for tight hamstrings in people with long-lasting low back pain: a special stretch and dry needling (thin needles placed in trigger points). It aims to find which helps reduce tightness and pain.
Peshawar, Khyber PakhtunkhwaAges 20–50 - NCT07474610Recruiting
Belly muscle and arm function in chronic low back pain
This study looks at how a deep belly muscle (transversus abdominis) relates to arm and shoulder function in people with long-term low back pain. It may help understand why some people have trouble with upper body movements.
AnkaraAges 18–45 - NCT04074798Recruiting
Breathing over fast and slow movements for back pain
This study tests how breathing changes (hyperventilation) might affect people with long-lasting low back pain. It may help researchers understand triggers or symptoms, and compare them to people who do not have back pain.
HasseltAges 20–60 - NCT05480982Recruiting
Cognitive functional therapy versus Pilates for low back pain
This study compares two exercise-based approaches—cognitive functional therapy and Pilates—to help reduce chronic low back pain in older adults. It may help by improving how you move and manage pain, not just stretching muscles.
Rio de Janeiro, Rio de JaneiroAges 65 years+ - NCT06928597Recruiting
GPR therapy for chronic low back pain
This study tests a physical therapy method called Global Postural Re-education (GPR) for people with long-term low back pain that is not caused by a specific disease. It aims to see if GPR can help reduce pain and improve function.
Salvador, Estado de BahiaAges 18–55 - NCT07523906Recruiting
Exercise therapy for chronic lower back pain in young adults
This study compares two types of exercise programs for chronic mechanical lower back pain: lumbar stabilization exercises (focused on core strength) versus muscular chain therapy (full-body movement patterns). You'll participate in one of these exercise programs to see which helps reduce your pain more effectively.
IslamabadAges 18–30 - NCT07603609Recruiting
Balance Platform Training for Chronic Low Back Pain
This study tests whether training on a special moving balance platform can help reduce chronic low back pain. You'll practice exercises designed to improve your balance and core stability over several weeks.
AnkaraAges 18–55 - NCT05269212Recruiting
Help people with ongoing back pain return to work
This study looks at how to help people with long-lasting spinal pain (PSPS-Type II) get back to work. It may help by testing a plan for managing persistent pain so work becomes more doable.
GhentAges 18–60 - NCT06704425Recruiting
How back pain affects thinking in older adults
This study looks at how chronic low back pain might affect memory, attention, and other thinking skills in adults aged 60 to 85. You will complete questionnaires, thinking tasks, and a brain scan to help researchers understand the link between pain and cognitive function.
Hong Kong, Hong KongAges 60–85 - NCT06102733Recruiting
Pelvic pain study for women and men
This trial is testing treatments for chronic pelvic pain, sacroiliac pain, groin pain, tailbone pain, and piriformis pain. It may help people with persistent pain in these areas find relief.
Surrey, British ColumbiaAges 20–99
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Common questions
- Are there clinical trials for chronic spinal pain?
- Yes. Clin2 currently lists 253 recruiting chronic spinal pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic spinal pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic spinal pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.