Clinical trials
Chronic Spinal Pain clinical trials
Below are recruiting chronic spinal pain clinical trials, each written for real people, not researchers. We’re tracking 253 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06892977Enrolling by invitation
How stress affects pain (brain scan study)
This study uses MRI scans to explore how stress changes your experience of pain. Researchers want to understand the link between stress and pain, which could help improve treatments for chronic pain.
GhentAges 18–45 - NCT06771713Recruiting
Brief Pain Reprocessing Therapy for Veterans with Chronic Back Pain
This trial tests a type of talk therapy called Brief Pain Reprocessing Therapy for Veterans with long-term low back pain. The therapy is done over video calls, so you can join from home. It aims to help retrain how your brain processes pain signals.
Ann Arbor, MichiganAges 18 years+ - NCT07413731Recruiting
Medication tapering with spinal cord stimulation
This trial tests how changing your pain medications while using a spinal cord stimulator affects your nervous system. It may help people with chronic lower back pain find the best way to manage their pain and reduce reliance on strong drugs.
WilrijkAges 18 years+ - NCT05461092RecruitingEarly Phase 1
Nerve blocks to improve pain control after spinal fusion
This early-stage study tests whether a regional nerve block can improve pain control and recovery for older adults having elective lumbar spinal fusion. If you qualify, you may receive a special pain-control injection during surgery to reduce opioid needs and improve recovery comfort.
Iowa City, IowaAges 65 years+ - NCT05459207Recruiting
Body fat and pain after spinal cord injury
This study looks at how body composition (amount and distribution of body fat) relates to pain in people with spinal cord injury. It may help researchers understand why pain differs from person to person after spinal cord injury.
Coral Gables, FloridaAges 18–70 - NCT07023497Recruiting
Finding the best dose of spinal morphine for C-section pain relief
This study tests different doses of morphine given through a spinal injection during a planned C-section to find the best balance of pain relief and side effects. It may help women have better pain control after surgery.
Ioannina, EpirusAges 18–50 - NCT05812885Recruiting
TENS for long-lasting low back pain
This study tests whether transcutaneous electrical nerve stimulation (TENS), a non-drug pain treatment using small electrode pads on the skin, can help people with low back pain. You may be eligible if your back pain has lasted at least 3 months and your pain is at least moderate.
West Hartford, ConnecticutAges 18–60 - NCT05467215RecruitingEarly Phase 1
Brief oxygen breathing trial after spinal cord injury
This early-phase study tests whether a short period of breathing extra oxygen (hyperoxia) soon after lying in one position can improve physical function in people with long-term spinal cord injury. If you qualify, the goal is to see whether this treatment can help your body work better after chronic injury.
Edmonton, AlbertaAges 18–65 - NCT06921694Recruiting
Exercise program for lower back pain
This trial tests a combined exercise program with stretching, strength, and aerobic exercises to help relieve chronic lower back pain. It looks at whether specific movements can reduce pain and improve daily function.
Nottingham, NottsAges 18–45 - NCT07127380Recruiting
Comparing two types of spine surgery for disc-related low back pain
This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.
Lodz, Łódź VoivodeshipAges 18 years+ - NCT07147296Recruiting
Implant to manage blood pressure swings after spinal cord injury
This trial tests an implanted device that may help control drops in blood pressure caused by spinal cord injury. If you often feel dizzy or lightheaded due to low blood pressure, this study could explore whether the device improves stability.
Little Rock, ArkansasAges 18–75 - NCT07211464Recruiting
ACT plus exercise for older adults with chronic low back pain
This study tests whether combining acceptance and commitment therapy (ACT) with exercise helps older adults manage ongoing low back pain. If you've had pain for at least 3 months and it's been bothering you, this approach might teach you new ways to cope and move better.
Hong KongAges 60 years+ - NCT05372822Recruiting
Testing a back pain therapy switch during spinal stimulation trial
This study tests whether changing the way spinal cord stimulation is used can better reduce long-lasting nerve pain down your leg. You must first complete a short spinal stimulation test period, and you should expect tingling during that testing time.
TrondheimAges 18 years+ - NCT06543277Recruiting
Nerve stimulation with hand therapy for spinal cord injury
This trial tests a safe, non-invasive nerve stimulation on the ear combined with arm and hand therapy to see if it can improve movement and function for people with neck-level spinal cord injury who still have some hand ability.
Houston, TexasAges 18 years+ - NCT07294651Recruiting
Needle treatment for chronic neck pain
This trial is testing a procedure called percutaneous electrolysis, where a tiny needle is used to treat painful trigger points in the upper neck muscles. It may help people with long-lasting neck pain.
SivasAges 18–70 - NCT05058287RecruitingPhase 3
Steroid shot during low-back surgery
This trial tests whether using a steroid medicine (a steroid shot) around the time of low-back decompression surgery improves pain and recovery. It is for adults having a limited-area laminectomy, and it compares steroid use versus not using it.
New York, New YorkAges 18–85 - NCT06874816Recruiting
Neck pain, teeth grinding, and mouth behaviors study
This trial looks at how chronic neck pain is linked to teeth grinding (bruxism) and other mouth-related habits. It aims to see if muscle thickness in your jaw is related to your neck pain.
Istanbul, BeylikdüzüAges 18–65 - NCT07544108Recruiting
Understanding What Affects Neck Pain Recovery
This study helps researchers understand which patients with long-term neck pain recover better and why. By learning more about your neck pain and how it affects your daily life, the study may help doctors predict outcomes and improve treatment.
Kütahya, KütahyaAges 18–65 - NCT07368920Recruiting
TENS for low back pain in adults
This study tests if a non-invasive device called TENS (which uses gentle electrical pulses) can help relieve low back pain that comes from muscle knots or tight bands. The device is applied to the skin over the painful area.
Xi'an, ShaanxiAges 18–65 - NCT06531317Recruiting
EEG and brain stimulation for nerve pain after spinal cord injury
This study tests whether a personalized brain stimulation treatment (using a non-invasive technique called tDCS) can help reduce nerve pain in people with spinal cord injury. The researchers will also use EEG (a cap that records brain activity) to see how your brain responds.
Badalona, BarcelonaAges 18–99 - NCT05851196Recruiting
Personalized exercise for recurrent low back pain
This study looks at how back muscle features can help tailor an exercise program for people with recurring, non-specific low back pain. It may help by matching exercises to your specific back function and symptoms.
DiepenbeekAges 18–60 - NCT06763653Recruiting
Low-frequency device for chronic low back pain
This trial tests a new device that uses very low-frequency electrical pulses to treat chronic low back pain. It is for people whose pain hasn't improved with other treatments and who are not candidates for stronger therapies.
Norwood, South AustraliaAges 22 years+ - NCT05811624Recruiting
Lifestyle program for weight and chronic low back pain
This trial studies whether a lifestyle change program (often diet and activity habits) can reduce long-lasting low back pain in overweight or obese adults. It also aims to see if people can keep their usual care while adding the lifestyle program.
BrusselsAges 18–65 - NCT07742111Recruiting
Virtual reality for long-term low back pain
This study tests whether virtual reality exercises can help people with chronic low back pain feel better and move more comfortably. You might join if you have had low back pain for a while, your pain is moderate, and you have some fear of movement.
AmaranteAges 18 years+
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Common questions
- Are there clinical trials for chronic spinal pain?
- Yes. Clin2 currently lists 253 recruiting chronic spinal pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic spinal pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic spinal pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.