Clinical trials
Chronic Stress clinical trials
Below are recruiting chronic stress clinical trials, each written for real people, not researchers. We’re tracking 47 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04701723Recruiting
Breathing training to help after trauma stress
This pilot study tests whether “cardiac coherence” breathing exercises can help prevent ongoing (chronic) post-traumatic stress disorder after a recent traumatic event. It’s meant for people who are newly dealing with an acute stress reaction, soon after the event.
Saint-PaulAges 18 years+ - NCT07313280Enrolling by invitation
PTSD and chronic pain therapy study for women
This study looks at how a psychological program can help women with chronic pain conditions linked to central sensitization (where the nervous system stays on high alert) and PTSD. It aims to reduce pain and stress symptoms.
Málaga, MálagaAges 18–65 - NCT02480283Recruiting
Study of cannabis smoke and lung immune response
This study compares people who smoke cannabis daily with people who have never used cannabis. It looks at how cannabis smoke affects lung stress and the lungs’ immune defenses, using health tests and urine screening to keep participants safe.
Aurora, ColoradoAges 18–55 - NCT06083480RecruitingPhase 4
Reducing stress to prevent long-term pain after knee replacement
This trial tests if lowering oxidative stress (damage from natural body processes) during knee replacement surgery can prevent chronic pain afterward. It may help people with osteoarthritis who have moderate to severe pain before surgery.
Nashville, TennesseeAges 50 years+ - NCT06885931Recruiting
Nerve stimulation trial for mixed urinary incontinence
This trial tests a new implant that stimulates a nerve in your pelvic area to help control both stress and urge urine leaks. It might be an option if you've tried other treatments like bladder training or medicine and they didn't help enough or caused side effects.
Leuven, Herestraat 49Ages 22 years+ - NCT07116109Recruiting
Brain Stimulation Plus Therapy for Pain and PTSD
This study tests whether a brain-stimulation headband (called tDCS) combined with a proven talk therapy for PTSD can help reduce both chronic pain and PTSD symptoms. It is for adults who have had chronic pain for at least 6 months and also have PTSD.
Charleston, South CarolinaAges 21 years+ - NCT04099992Recruiting
Mindfulness program for people with chronic kidney disease
This trial tests whether a mindfulness-based program can help people living with moderate-to-advanced kidney disease. It may improve how you feel day-to-day and how you manage symptoms, while researchers track kidney-related health and safety.
Atlanta, GeorgiaAges 40–80 - NCT06070766Recruiting
At-home ketamine study for chronic conditions
This trial tests a ketamine protocol you can use at home. It may help if you have a long-term health condition.
Bigfork, MontanaAges 18 years+ - NCT05183503Enrolling by invitation
Study of pain, stress, anxiety, and depression in jaw disorder
This study looks at how chronic jaw pain from temporomandibular disorder (TMD) relates to stress, anxiety, and depression in adults. Your results may help researchers better understand what affects symptoms and how people respond to care.
WroclawAges 18–80 - NCT07437729Recruiting
Glycocalyx and stress in blood vessel health
This study looks at how a protective layer inside your blood vessels (called the glycocalyx) and stress in the body relate to blood pressure and kidney health. Doctors want to compare people with high blood pressure and different stages of kidney damage to healthy volunteers.
OsijekAges 18 years+ - NCT07522944Recruiting
AI Relaxation Tool to Reduce Dialysis Anxiety
This study tests whether an artificial intelligence-guided relaxation program can help reduce anxiety in patients undergoing hemodialysis. The program uses calming visuals and sounds delivered through a digital platform to help you feel less anxious during your dialysis sessions.
Alexandria, Alexandria GovernorateAges 18 years+ - NCT06892977Enrolling by invitation
How stress affects pain (brain scan study)
This study uses MRI scans to explore how stress changes your experience of pain. Researchers want to understand the link between stress and pain, which could help improve treatments for chronic pain.
GhentAges 18–45 - NCT05677412Recruiting
Studying sleep, stress, and pain in teens with ongoing pain
This study looks at how sleep and stress relate to pain that keeps coming back in teens. It may help researchers understand what could improve comfort and daily functioning when pain lasts more than three months.
HelsinkiAges 15–17 - NCT07136584Recruiting
Support for caregiver wellbeing study
This study is testing a program to support the mental health of parents whose children are being treated for neuromuscular disorders or diabetes at the Royal Children's Hospital. If you are a parent able to fill out a consent form in English without an interpreter, you may be able to join.
Parkville, VictoriaAges Any age - NCT07431658Enrolling by invitation
Diet and stress effects on omalizumab response in chronic hives
This study looks at how diet and oxidative stress (a type of cell damage) affect the severity of chronic hives and how well patients respond to the medication omalizumab (Xolair). It may help find ways to improve treatment by understanding these factors.
IstanbulAges 18–65 - NCT06185530Recruiting
Comparing stress echo vs CT scan for chest pain
This trial compares two heart imaging tests (stress echo with ultrasound of the neck, and a CT scan) to see which one better helps guide treatment for people with chest pain that might be from heart disease. If you have chest pain that is typical for heart disease, you may be able to join.
Harrow, MiddxAges 18 years+ - NCT07213063Recruiting
Creatine and HMB supplements for Down syndrome
This trial tests whether taking creatine and HMB supplements can improve muscle strength, reduce inflammation, and increase muscle mass in people with Down syndrome. It may help if you or your loved one can do basic physical tests like standing from a chair and do not have kidney disease or severe mobility issues.
Burgos, BurgosAges 18 years+ - NCT07123922Enrolling by invitation
Silymarin for COPD: A Study on Breathing and Quality of Life
This study tests whether adding silymarin (a herbal supplement from milk thistle) to your regular COPD treatment can improve your lung function, reduce stress in your body, and help you feel better day-to-day.
DhakaAges 40–80 - NCT06275399Recruiting
Study of plaque and platelets in narrowed heart arteries
This study looks at how plaque buildup and blood platelets interact in partially blocked heart arteries. It might help find better ways to treat people with chronic coronary syndrome.
Warsaw, Masovian VoivodeshipAges 18 years+ - NCT05172739RecruitingPhase 4
Opioid-free anesthesia during lung surgery for early lung cancer
This study tests whether an opioid-free pain/anesthesia plan during elective lung surgery can reduce surgical “stress” on the body and affect the immune system. You may be eligible if you have early-stage non-small cell lung cancer and are scheduled for a specific type of surgery (VATS lobectomy).
Heraklion, CreteAges 18–80 - NCT06073886RecruitingPhase 2
Better brain stimulation for long-lasting concussion symptoms
This trial tests whether personalized brain stimulation can help people who have ongoing symptoms more than 20 on a standard concussion scale, such as headaches, dizziness, or trouble concentrating, after a mild head injury in the past year.
Westwood, Los Angeles, CaliforniaAges 18–65 - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+
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Common questions
- Are there clinical trials for chronic stress?
- Yes. Clin2 currently lists 47 recruiting chronic stress studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic stress trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic stress trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.