Clinical trials
Clonal Hematopoiesis clinical trials
Below are recruiting clonal hematopoiesis clinical trials, each written for real people, not researchers. We’re tracking 21 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07590804Recruiting
Plant-Based Diet Study for Blood Cell Cloning
This study tests whether eating more plant-based whole foods can help people with clonal hematopoiesis (a condition where blood cells grow from a single mutated cell). Researchers want to understand if dietary changes affect this condition and collect health information over time.
Basking Ridge, New JerseyAges 18 years+ - NCT07362966RecruitingPhase 4
Colchicine for heart health after a heart attack
This study tests whether a low-dose medicine called colchicine can reduce inflammation and slow down artery blockages in people who have a specific gene change (TET2) and have recently had a heart attack. The goal is to see if it helps prevent future heart problems.
Shenyang, LiaoningAges 40–85 - NCT07675967Recruiting
Blood Cell Changes During Cancer Treatment
This study is for people with solid tumors who are about to start chemotherapy or radiation. It looks at how these treatments affect blood cells and may help doctors understand changes in blood health over time.
Boston, MassachusettsAges 18 years+ - NCT06701214Recruiting
Blood cell mutations and inflammation registry
This study collects blood samples and health information from people with certain unexplained blood cell changes or those at higher risk for them, to learn how these changes relate to inflammation and heart health.
Nashville, TennesseeAges 18 years+ - NCT05246813Recruiting
Study blood cell changes in older adults
This study looks at how blood-forming stem cells change in people with clonal hematopoiesis (CHIP), a common age-related blood condition. It may help researchers understand what these changes mean and who might be at higher risk for future blood problems.
Bonheiden, BelgiëAges 55 years+ - NCT06295965Recruiting
Blood changes and cancer therapy study
This study looks at why some people develop blood disorders after cancer treatment. It monitors changes in blood cells to better predict and prevent these problems.
Seattle, WashingtonAges Any age - NCT07313059Recruiting
Clonal hematopoiesis study for people 55+
This study looks at a condition called clonal hematopoiesis (CH), where some blood cells have changes that may affect their health. It aims to prevent, treat, and better understand CH. You may qualify if you are 55 or older and have low blood counts that persist over time.
Canberra, Australian Capital TerritoryAges 55 years+ - NCT05711173Recruiting
Study blood clot triggers and immune cell changes in clot patients
This study looks at how certain blood cell changes and immune system activity may relate to blood clots in specific veins or lungs. It may help researchers understand why clots happen “without a clear cause” and how to better predict risk.
BordeauxAges 6–50 - NCT06870760Recruiting
Early blood cancer detection in Charlotte firefighters
This study looks at firefighters to find early signs of blood cancers before they become serious. It aims to learn how to catch these cancers earlier, so they can be treated sooner.
Charlotte, North CarolinaAges 40–49 - NCT04102423Recruiting
Study of CHIP and CCUS to track blood health changes
This study follows adults who have certain blood-cell DNA changes (CHIP or CCUS) to learn how their condition may progress over time. It mainly looks at natural history—what happens in the blood without giving an active treatment.
Bethesda, MarylandAges 18–99 - NCT02958462Recruiting
Clinic study for early blood or bone marrow warning signs
This study follows people who may have early, unclear blood count problems or certain genetic/immune patterns that can later lead to bone marrow failure or blood cancers. It may help doctors better understand risks over time and guide earlier care.
Scottsdale, ArizonaAges 18 years+ - NCT04711746Recruiting
Clonal blood changes after certain lung blood clots
This study looks at whether a specific kind of blood-cell change (“clonal hematopoiesis”) is linked to a lung blood clot (pulmonary embolism) that happened without a clear trigger. It compares people with unprovoked clots to people with provoked clots, after checking for inherited clotting risk factors.
AmiensAges 18–65 - NCT07188740RecruitingPhase 1
Metformin to target leukemia-related mutation during remission
This trial tests if metformin can reduce a specific mutation (DNMT3A R882) in people with acute leukemia who are in remission. The goal is to see if it helps prevent relapse.
Tianjin, Tianjin MunicipalityAges 14 years+ - NCT04689750Recruiting
Testing outcomes after donor CHIP in stem cell transplant
This study looks at how a genetic risk factor in a stem cell donor (called CHIP) may affect outcomes after an allogeneic (donor-to-recipient) stem cell transplant. It may help doctors better predict which donor factors are important for patient outcomes.
Hong KongAges 18 years+ - NCT06691217RecruitingPhase 2
Testing an Anti-Inflammatory Drug for Heart Disease With TET2 Mutation
This study tests whether a medication that blocks inflammation (called an IL-1 beta inhibitor) can reduce blood vessel inflammation in people with both heart disease and a specific genetic change in their blood cells (TET2 mutation). It aims to see if targeting this type of inflammation can help lower heart risks.
Boston, MassachusettsAges 18 years+ - NCT05705531Recruiting
Cardiac MRI study of heart health after Hodgkin lymphoma treatment
This study looks at how certain blood-related “growth patterns” connect to long-term heart health after treatment for classical Hodgkin lymphoma. It may help doctors better predict who could develop heart problems and how to monitor them over time.
Mobile, AlabamaAges 7 years+ - NCT07249840RecruitingPhase 1
Testing ropeginterferon for high-risk JAK2 mutation carriers
This trial tests whether the drug ropeginterferon can help people with a JAK2 gene mutation who have additional risk factors but do not yet have a blood cancer. The goal is to see if treatment can prevent blood clots, high blood counts, or other complications.
Boston, MassachusettsAges 18 years+ - NCT04053439Recruiting
Testing blood-clone risk to prevent chemotherapy complications
This study looks at a specific genetic/production change in blood-forming cells (“clonal hematopoiesis”) to understand who is more likely to have complications from lymphoma chemotherapy. It may help doctors predict risk and possibly reduce harmful side effects.
Toronto, OntarioAges 60 years+ - NCT04541654Recruiting
Study of families with TP53 gene changes in Li-Fraumeni syndrome
This study is looking at how people in families with certain TP53 gene changes (including Li-Fraumeni syndrome) develop health problems over time. It may help doctors better understand risk and improve care for affected families.
Boston, MassachusettsAges Any age - NCT02604563Recruiting
Aging, blood changes, and health in older adults
This study examines why some older adults develop changes in their blood cells that may affect their health. Researchers will look for links between these blood changes, aging, and common health problems in older people.
St Louis, MissouriAges 50 years+ - NCT06626685Recruiting
Clonal blood cells in heart failure
This study looks at whether changes in blood cells (called clonal hematopoiesis) are linked to heart failure. By testing your blood, researchers hope to learn more about how heart failure progresses and find new ways to treat it.
BergamoAges 18 years+
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Common questions
- Are there clinical trials for clonal hematopoiesis?
- Yes. Clin2 currently lists 21 recruiting clonal hematopoiesis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a clonal hematopoiesis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a clonal hematopoiesis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.