Cognition Improvement clinical trials

Exercise for heart and brain health in premature children

This study tests whether a supervised exercise program can help children born prematurely (before 32 weeks) improve their heart health and thinking skills. It's designed for children ages 6 to 12 who are otherwise healthy and not receiving special education for attention problems.

Testing ways to improve thinking after bone marrow transplant

This study looks at whether a physical activity program and related study measures can improve thinking and memory in older adults around the time of a stem cell transplant. If you qualify and participate, the team will compare outcomes between groups to see what approach works best.

Test dual-task walking to improve thinking in colorectal cancer

This study looks at a walking exercise that makes you do two tasks at once (for example, walking while focusing on something) to see if it can improve thinking and memory. It is for people newly diagnosed with early to mid-stage colorectal cancer, and excludes people with other cancers or cancer coming back.

Warmth and TENS to improve thinking in dementia

This study tests whether using a warmth treatment and a gentle electrical nerve-stimulation device (TENS) can improve thinking and memory in people with mild to moderate dementia. It may help by supporting brain and nerve function, alongside your usual care.

Music program to improve thinking in people with multiple sclerosis

This study tests a music-based program to see if it can help improve thinking and memory in people with multiple sclerosis. It is a small feasibility study to see if the program is practical and helpful.

Retraining Neural Pathways Improves Cognitive Skills After A Mild Traumatic Brain Injury

SuperCAP: An App Program to Help Post-COVID Brain Fog

This study tests a smartphone app designed to help people with long-COVID improve their thinking and daily activities. You'll use the app about 15 minutes a day, 5 days a week, to work on cognitive skills and functioning.

Brain training to improve self-control in internet gaming disorder

This study tests a brain-training technique that uses a brain-computer interface to help people with internet gaming disorder improve self-control. You would attend sessions where you learn to control brain activity, which may help you reduce excessive gaming.

Yoga for better thinking with heart failure

This trial tests if a yoga program can help improve memory and thinking in people with heart failure. It's designed for adults 55 and older who are not already doing yoga and are able to take part in gentle physical activity.

Can light therapy help 'chemo brain' after breast cancer?

This study tests whether a special light therapy (photobiomodulation) can help improve the 'chemo brain' – memory and thinking problems – that some women experience after breast cancer chemotherapy. If you've had memory issues since chemo and finished treatment within the past year, you may be able to join.

Sleep app study for California firefighters

This trial tests a smartphone app designed to help firefighters sleep better, think more clearly, and feel better overall. You might join to improve your sleep and health through a simple program on your iPhone or iPad.

Goal management training for cognitive control after brain injury

This trial tests a training program called Goal Management Training (GMT) to help people who have had a brain injury improve their ability to plan, focus, and stay organized. If you have trouble with these skills and your injury happened at least a year ago, this training might help you get better at everyday tasks.

Brain training to improve control over emotional eating

This study tests a brain training technique (neurofeedback) that may help improve self-control related to emotional eating. If you tend to eat more when stressed or upset, this could help you manage those urges.

Hand stimulation for thinking problems after stroke

This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.

Can extending nightly fasting improve sleep and thinking in breast cancer survivors?

This study tests whether eating all your meals within a shorter window each day (prolonged nightly fasting) can help improve sleep and thinking skills in breast cancer survivors who have memory or concentration problems.

Brain stimulation to improve thinking after stroke

This study tests whether a noninvasive brain stimulation treatment can improve thinking and memory problems after an acute ischemic stroke. It also uses brain scans to better understand how the treatment may help.

Brain stimulation to improve symptoms and thinking in schizophrenia

This study tests whether a gentle electrical current applied to the scalp (transcranial alternating current stimulation, or tACS) can help reduce negative symptoms and improve thinking in people with long-term schizophrenia. It is for patients who have been hospitalized for over six months and are on stable medication.

Wearable robotic exoskeleton to improve walking and thinking in MS

This study tests a wearable robotic exoskeleton to help people with multiple sclerosis walk better and improve thinking/problem-solving. You would use the device during supervised sessions and take brief thinking and movement checks to see if it’s safe and helpful for you.

Cognitive therapy for adjusting to vision loss

This study tests new ways to help people adjust to vision loss using thinking and coping strategies. If you are an adult with vision loss and willing to share feedback, this may be a good fit.

Light, sound, and touch therapy for Parkinson’s symptoms

This trial tests whether high-frequency light, sound, and gentle touch can improve movement and thinking problems in people with Parkinson’s disease. You may help the researchers learn if this kind of stimulation is safe and beneficial alongside your usual Parkinson’s medications.

Brain stimulation for balance and thinking in older adults with glaucoma

This study tests a non-invasive brain stimulation technique to see if it can improve balance and thinking in older adults with glaucoma. It involves a series of sessions where a mild electrical current is applied to the brain.

Can light therapy help balance and thinking in adults over 60?

This trial tests whether shining a special light on the forehead (called photobiomodulation) can improve balance and memory in healthy adults aged 60 to 80. It's a small study to see if the approach is safe and feasible.

Brain stimulation study for mild memory problems

This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.

Testing brain stimulation to improve memory in mild impairment

This study tests whether a noninvasive brain stimulation method (tACS) can improve memory in people with mild cognitive impairment (MCI). A caregiver also helps with the stimulation during the study, and success is measured through study visits and memory-related evaluations.