Clinical trials
Cognition Improvement clinical trials
Below are recruiting cognition improvement clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04796506Recruiting
Tracking sleep changes to improve thinking in Parkinson’s
This study looks at whether changes in “slow wave sleep” (a deep sleep stage) match improvements in thinking for people with Parkinson’s. It uses an exercise/recovery-focused approach and checks sleep and thinking scores to see if these changes go together.
Aurora, ColoradoAges 45–100 - NCT04898790Recruiting
Testing ways to improve thinking after bone marrow transplant
This study looks at whether a physical activity program and related study measures can improve thinking and memory in older adults around the time of a stem cell transplant. If you qualify and participate, the team will compare outcomes between groups to see what approach works best.
Omaha, NebraskaAges 19 years+ - NCT06052176RecruitingPhase 2
Albumin for better thinking in liver disease
This trial tests if weekly albumin infusions can improve thinking problems (called hepatic encephalopathy) in people with cirrhosis. You may be eligible if you have cirrhosis, some memory or concentration issues, and have been taking lactulose or rifaximin for at least a month.
Richmond, VirginiaAges 18 years+ - NCT06465823RecruitingPhase 2
Bumetanide for thinking skills in Down syndrome
This trial tests whether a medication called bumetanide can improve thinking and learning skills in teenagers with Down syndrome. It is a 10-week study that compares bumetanide to a placebo (a pill with no medicine).
RomeAges 10–17 - NCT06500910Recruiting
Exercise for heart and brain health in premature children
This study tests whether a supervised exercise program can help children born prematurely (before 32 weeks) improve their heart health and thinking skills. It's designed for children ages 6 to 12 who are otherwise healthy and not receiving special education for attention problems.
Basel, Canton of Basel-CityAges 6–12 - NCT07040748Recruiting
Virtual reality training to boost thinking skills
This trial tests if immersive virtual reality exercises can improve thinking and memory in adults with metabolic syndrome. It may help if you have noticed some cognitive changes and want to try a non-drug approach.
TerrassaAges 45–70 - NCT07041502Recruiting
Aut-CARE: Helping young autistic adults think and feel better
This study tests an online program for young adults (16-30) with autism to help them think more clearly, solve problems, and manage emotions. It's designed for people without intellectual disability who already attend services at the Friends Foundation.
Barcelona, CataloniaAges 16–30 - NCT07055633Recruiting
Improving cognitive rehab for veterans with concussion and PTSD
This trial tests a program to help veterans with memory, attention, or thinking problems after a mild concussion (mTBI) and with PTSD. It also looks at depression and sleep issues. The goal is to improve thinking and daily life.
San Diego, CaliforniaAges 18 years+ - NCT07122908RecruitingPhase 1/Phase 2
Magnetic brain stimulation for thinking in Lewy body dementia
This trial tests a noninvasive magnetic brain stimulation (rTMS) treatment for people with dementia with Lewy bodies. The treatment aims to help improve thinking and memory. It involves 1–2 weeks of daily sessions, and you'll have memory tests and brain scans during the study.
Seoul, SeoulAges 65 years+ - NCT07189442Recruiting
L-theanine and paraxanthine for focus in adults with ADHD or autism
This trial tests two natural compounds to see if they help improve thinking and focus in adults with ADHD or autism. You'll take the supplements or a placebo and do some tasks while having brain scans.
Lubbock, TexasAges Any age - NCT07229924Recruiting
Cognitive improvement after weight-loss surgery with virtual reality
This trial tests whether a virtual reality exercise program can help improve thinking skills (like memory and attention) after bariatric (weight-loss) surgery. It may benefit people with severe obesity who are planning to have surgery.
Montreal, QuebecAges 18–65 - NCT07489105Recruiting
Yoga for better thinking with heart failure
This trial tests if a yoga program can help improve memory and thinking in people with heart failure. It's designed for adults 55 and older who are not already doing yoga and are able to take part in gentle physical activity.
Auburn, AlabamaAges 55 years+ - NCT06995443Recruiting
Can light therapy help 'chemo brain' after breast cancer?
This study tests whether a special light therapy (photobiomodulation) can help improve the 'chemo brain' – memory and thinking problems – that some women experience after breast cancer chemotherapy. If you've had memory issues since chemo and finished treatment within the past year, you may be able to join.
ValenciennesAges Any age - NCT07477184Recruiting
Sleep app study for California firefighters
This trial tests a smartphone app designed to help firefighters sleep better, think more clearly, and feel better overall. You might join to improve your sleep and health through a simple program on your iPhone or iPad.
San Luis Obispo, CaliforniaAges 18 years+ - NCT06604000Recruiting
Goal management training for cognitive control after brain injury
This trial tests a training program called Goal Management Training (GMT) to help people who have had a brain injury improve their ability to plan, focus, and stay organized. If you have trouble with these skills and your injury happened at least a year ago, this training might help you get better at everyday tasks.
TrondheimAges 18–65 - NCT07736885Recruiting
Hand stimulation for thinking problems after stroke
This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.
Tianjin, Tianjin MunicipalityAges 35–80 - NCT06938555Recruiting
Can extending nightly fasting improve sleep and thinking in breast cancer survivors?
This study tests whether eating all your meals within a shorter window each day (prolonged nightly fasting) can help improve sleep and thinking skills in breast cancer survivors who have memory or concentration problems.
Phoenix, ArizonaAges 18 years+ - NCT05195398Recruiting
Brain stimulation to improve thinking after stroke
This study tests whether a noninvasive brain stimulation treatment can improve thinking and memory problems after an acute ischemic stroke. It also uses brain scans to better understand how the treatment may help.
Baltimore, MarylandAges 18–100 - NCT07074704Enrolling by invitation
Brain stimulation to improve symptoms and thinking in schizophrenia
This study tests whether a gentle electrical current applied to the scalp (transcranial alternating current stimulation, or tACS) can help reduce negative symptoms and improve thinking in people with long-term schizophrenia. It is for patients who have been hospitalized for over six months and are on stable medication.
Shanghai, Shanghai MunicipalityAges 18–65 - NCT04855825Recruiting
Wearable robotic exoskeleton to improve walking and thinking in MS
This study tests a wearable robotic exoskeleton to help people with multiple sclerosis walk better and improve thinking/problem-solving. You would use the device during supervised sessions and take brief thinking and movement checks to see if it’s safe and helpful for you.
West Orange, New JerseyAges 18–75 - NCT07073521Recruiting
Cognitive therapy for adjusting to vision loss
This study tests new ways to help people adjust to vision loss using thinking and coping strategies. If you are an adult with vision loss and willing to share feedback, this may be a good fit.
Chicago, IllinoisAges 18 years+ - NCT07771699Recruiting
Brain stimulation for balance and thinking in older adults with glaucoma
This study tests a non-invasive brain stimulation technique to see if it can improve balance and thinking in older adults with glaucoma. It involves a series of sessions where a mild electrical current is applied to the brain.
Kowloon, Hong KongAges 55 years+ - NCT05268887Recruiting
Light, sound, and touch therapy for Parkinson’s symptoms
This trial tests whether high-frequency light, sound, and gentle touch can improve movement and thinking problems in people with Parkinson’s disease. You may help the researchers learn if this kind of stimulation is safe and beneficial alongside your usual Parkinson’s medications.
Cambridge, MassachusettsAges 45–90 - NCT07260903Recruiting
Can light therapy help balance and thinking in adults over 60?
This trial tests whether shining a special light on the forehead (called photobiomodulation) can improve balance and memory in healthy adults aged 60 to 80. It's a small study to see if the approach is safe and feasible.
Preston, LancashireAges 60–80
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Common questions
- Are there clinical trials for cognition improvement?
- Yes. Clin2 currently lists 110 recruiting cognition improvement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition improvement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition improvement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.