Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06248723Recruiting
Preventing memory decline in older adults with lifestyle changes
This study tests a personalized program of lifestyle changes (diet, exercise, brain training, etc.) to see if it can prevent memory loss and keep older adults independent. You may qualify if you are 60+, have mild frailty, and have certain risk factors for dementia.
MonzaAges 60 years+ - NCT06687161Recruiting
Treating insomnia in mild memory problems
This study tests whether a non-invasive brain stimulation method (TMS) combined with cognitive training can improve sleep in older adults with mild memory issues. It may help if you have trouble falling or staying asleep and have early memory changes.
Boston, MassachusettsAges 60 years+ - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT05731414Recruiting
Testing behavior programs to improve outcomes in schizophrenia
This study looks at how a behavioral program (including remediation and behavior-based techniques) may improve outcomes for adults with schizophrenia-spectrum conditions. You may be eligible if you meet basic age/language needs and haven’t done certain therapies recently.
Scarborough Village, OntarioAges 18–65 - NCT06627894Recruiting
Online therapy for depression after ICU stay
This trial tests if an online cognitive behavioral therapy program can help reduce depression and slow down thinking and memory problems in older adults who have been in the intensive care unit (ICU). It looks at whether treating depression can protect your brain health after a serious illness.
Indianapolis, IndianaAges 50 years+ - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Atlantis, FloridaAges 60–90 - NCT06507254Recruiting
Polyphenols and brain health in aging
This study tests whether eating more polyphenols (natural compounds in plants) can protect brain health in people at higher risk for Alzheimer's disease, especially if they currently eat a typical Western diet. Participants will be followed over time to see if changes in diet affect thinking and memory.
Los Angeles, CaliforniaAges 50 years+ - NCT05456035Recruiting
Talk-therapy plus social skills training for depressed teens
This study tests whether adding social-cognitive training (skills for understanding social situations and thoughts) to regular talk therapy helps teens with depression. It may help improve mood and daily functioning compared with talk therapy alone.
Nashville, TennesseeAges 13–17 - NCT05114876Recruiting
Tested a new plan to support older adults after surgery
This study looks at a redesigned surgical care plan to better support older adults who may have memory or thinking changes after major planned surgery. If you qualify, you would be assessed before surgery and followed after to see whether this approach helps.
Toronto, OntarioAges 60 years+ - NCT06448403Recruiting
Alzheimer's assessment study with brain scans
This study uses brain scans (MRI and EEG) to better understand Alzheimer's disease. It compares people with MCI or Alzheimer's to healthy volunteers to see how the disease affects the brain.
Trondheim, TrønderlagAges 65 years+ - NCT05149742Recruiting
Study of hearing loss and thinking skills in midlife adults
This study looks at how severe hearing loss affects thinking and memory in adults aged 45–64. Researchers will compare people with significant hearing loss to people with normal hearing who are similar in age, sex, and education.
ParisAges 45–64 - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06408103Recruiting
Brain health program for you and your caregiver
This study tests a program that combines exercise, nutrition, and mental activities for both you and your family caregiver. It aims to help keep your thinking and memory skills strong.
Bucaramanga, Santander DepartmentAges 55 years+ - NCT06379594Enrolling by invitation
Remote brain health clinic for mild memory problems
This study tests a remote 'brain health clinic' for people with mild memory or thinking problems (mild cognitive impairment). It aims to help diagnose the cause of memory issues from home, so you don't need to travel to a clinic.
London, Denmark HillAges 18 years+ - NCT06392945Recruiting
Walking and thinking training with music for chronic stroke recovery
This trial tests whether adding a rhythmic beat (like a metronome or music) to walking while doing thinking tasks can improve walking after a stroke. It is for people who had a stroke more than 6 months ago and can already walk a short distance.
TaipeiAges 20–85 - NCT06347315Recruiting
Studying a nutritional drink for mild memory loss in older adults
This study tests whether a special drink containing medium-chain triglycerides (MCTs, a type of fat) and B vitamins can help support memory and thinking in older adults with mild cognitive impairment (MCI). You would take the drink daily for 18 months and have regular check-ins including memory tests.
BronAges 60 years+ - NCT06268080Recruiting
Sedation depth and mental recovery after surgery for older adults
This trial tests whether monitoring how deeply you sleep during anesthesia helps prevent confusion and memory problems after surgery. It is for older adults who can give consent and are having a major operation.
Grafton, AucklandAges 55 years+ - NCT06286202Recruiting
Cognitive skills program for schizophrenia recovery
This trial tests a community-based program called INSPIRE that uses mental exercises and social coaching to help people with schizophrenia or schizoaffective disorder improve their thinking skills and daily functioning. It is conducted in English and requires at least 10 years of English-language education.
SingaporeAges 21–60 - NCT06223672Recruiting
Healthy fats for better thinking in older adults
This study tests whether healthy fats can help improve thinking and memory in people with mild memory concerns. It is for people with overweight and normal blood sugar.
Columbus, OhioAges 40–75 - NCT04191811Recruiting
Using brain signals to predict CBT success for mood or sleep issues
This study tests whether brain measurements can help predict who will benefit from a type of talk therapy called CBT (cognitive behavioral therapy). If you have depression, social anxiety, or insomnia, your brain “response variability” may be used to personalize or improve treatment planning.
Huddinge, Stockholm CountyAges 18 years+ - NCT06086379Enrolling by invitation
Cognitive rehab therapy for COVID-related thinking problems in Veterans
This study tests a cognitive rehabilitation therapy designed to help Veterans who have memory and thinking problems after COVID-19. It aims to improve daily mental function and quality of life.
San Diego, CaliforniaAges 18 years+ - NCT06095063Recruiting
Magnetic brain stimulation for memory concerns with family Alzheimer's history
This study tests whether a type of magnetic brain stimulation (dTMS) can help people who are worried about their memory. It is for people who have a family history of Alzheimer's but are still thinking clearly.
Toronto, OntarioAges 55–70 - NCT06095297Recruiting
Cognitive rehab for brain fog from long COVID
This study tests a computer-based cognitive training program combined with a gentle nerve stimulation device to see if it can improve brain fog and daily functioning in people with long COVID. If you're struggling with thinking, memory, or concentration after COVID, this might help.
Birmingham, AlabamaAges 18 years+ - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 1,981 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.