Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06032377Recruiting
Online therapy for sleep and brain health in older adults
This study tests an online talk therapy program (CBT) to help older adults with both sleep troubles and mild memory or thinking concerns. It's done from home, and aims to improve sleep and brain health.
Ottawa, OntarioAges 60–99 - NCT06000475Recruiting
Memory boosting therapy for PTSD in veterans
This trial is testing a type of therapy called Cognitive Processing Therapy (CPT) for PTSD, along with memory exercises to help enhance the therapy's effects. It is for veterans who have PTSD and want to see if adding memory training can improve their treatment.
Philadelphia, PennsylvaniaAges 60 years+ - NCT05977439Recruiting
Brain training for depression recovery
This study uses brain imaging and stimulation to help people with depression learn how to regulate their emotions better. It aims to find out if targeting specific brain networks can improve symptoms.
Charleston, South CarolinaAges 18–65 - NCT05949047Recruiting
Phone-based training for family caregivers of Alzheimer’s patients
This study tests a smartphone program that teaches skills to better manage emotions for people who provide unpaid care for someone with Alzheimer’s disease. It may help caregivers feel less overwhelmed and cope more effectively during daily stress.
Houston, TexasAges 18 years+ - NCT05947045Recruiting
Virtual reality cognitive training during brain tumor radiotherapy
This trial tests whether a computer-based cognitive training program in a virtual reality setting can help children think and learn while they are getting radiation for a brain tumor. You and a parent will decide together if it’s a good fit, and the child must be able to complete the study tasks.
Memphis, TennesseeAges 8–22 - NCT05948930Recruiting
Exercise and brain training for mild memory problems
This study tests whether a mix of physical exercise and computer brain training can improve working memory in people with mild cognitive impairment (MCI). It may help by strengthening memory skills and supporting brain health through supervised activity and computer-based practice.
Baltimore, MarylandAges 50–80 - NCT05864274Recruiting
Cognitive training for people on chemotherapy
This trial studies a phone or tablet brain-training program to help with “cancer-related cognitive impairment,” or thinking and memory problems that can happen during chemotherapy. If you’re newly diagnosed with certain gynecologic cancers and are receiving chemotherapy, this may help you see whether the training improves cognitive symptoms.
Birmingham, AlabamaAges 18–90 - NCT05888961Recruiting
Study of taste changes in people with memory problems
This study tracks how taste perception works in people with different stages of memory and thinking problems, including mild to moderate Alzheimer-type conditions. It uses non-painful taste testing and brain-wave measurements to understand changes over time and may help improve how these conditions are assessed.
DijonAges 18 years+ - NCT05890183Recruiting
Telehealth exercise and brain training after a first psychosis episode
This trial tests whether a combination of at-home (telehealth) aerobic exercise and computer-based cognitive training can improve thinking and day-to-day function after a first episode of schizophrenia-spectrum illness. It may help by strengthening attention and learning skills after the initial psychotic episode.
Los Angeles, CaliforniaAges 18–45 - NCT05877196Recruiting
Adaptive walking and fitness program for mild memory decline
This study tests an “adaptive” exercise plan that adjusts over time to help improve aerobic fitness and your body’s fitness response in people with mild memory problems or early Alzheimer’s. It may help you safely build the kind of fitness that supports brain health, while researchers monitor changes with fitness testing and blood work.
Phoenix, ArizonaAges 65 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT04970888Recruiting
Exercise program to improve thinking and brain blood flow in heart failure
This trial tests whether doing a combined mental (cognitive) and physical exercise program can improve thinking and how well blood flows to the brain in people with chronic heart failure. It may help by strengthening both brain function and physical capacity while your heart condition stays stable.
Montreal, QuebecAges 50 years+ - NCT05770479Enrolling by invitation
Testing long-lasting cognitive training for older veterans
This study looks at whether a cognitive training program you’ve already completed can keep helping over time, and whether it can be improved with “booster” sessions. It may help older veterans maintain thinking and daily functioning skills after earlier training.
San Diego, CaliforniaAges 55 years+ - NCT05708716Recruiting
Diet and brain training for people after blood cancer
This study tests whether a combined diet plan and structured brain (cognitive) training can improve thinking and memory in people who have had blood cancer. It may help survivors who already have mild-to-moderate thinking problems.
Birmingham, AlabamaAges 21 years+ - NCT05624632Enrolling by invitation
Online cognitive tests you can do remotely
This study checks how well an online remote testing approach measures thinking and memory. It may help researchers collect cognitive data more easily, especially by combining it with other related studies.
BarcelonaAges 45–80 - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT05446584RecruitingPhase 2
Study memory changes in people with past mild head injury
This Phase 2 study looks at how memory problems (amnestic mild cognitive impairment) may relate to a history of a mild traumatic brain injury. It compares people with a past mild head injury to people without one to better understand what might be driving memory symptoms.
Dallas, TexasAges 55 years+ - NCT05372172Recruiting
Tennessee Alzheimer’s study for people 60 and older
This study is looking at how brain and memory changes show up in people across the Alzheimer’s spectrum—from normal thinking to mild memory problems to Alzheimer’s disease. You might join if you can do study visits and an MRI and have a reliable study partner available.
Nashville, TennesseeAges 60 years+ - NCT05336201RecruitingPhase 2
Brain training program for teens with sickle cell disease
This Phase 2 study tests a cognitive (thinking) training program to help teens with sickle cell disease prepare for the changes in their care as they grow older. It may help with skills like learning, attention, and planning for transition to adult care.
Birmingham, AlabamaAges 10–18 - NCT05176561Enrolling by invitation
Brain and hearing training for older cochlear-implant users
This trial studies whether a structured auditory (hearing) and cognitive (thinking) training program can improve outcomes for adults who use cochlear implants. It’s designed for people at a certain stage after their implant and with specific hearing and thinking test results.
Washington D.C., District of ColumbiaAges 60 years+ - NCT05079464Recruiting
Exercise plus brain stimulation to improve memory in early impairment
This trial tests whether a supervised exercise program, paired with brain stimulation, can improve thinking and memory in people with early “vascular” cognitive problems (not dementia). It may help your brain function before memory loss becomes more severe.
Toronto, OntarioAges 50 years+ - NCT05042102RecruitingPhase 2
Donepezil plus brain training for alcohol use disorder
This Phase 2 study tests whether donepezil, along with structured cognitive (brain) training, can improve outcomes for people with alcohol use disorder. It will measure whether this combination helps after recent heavy drinking, while tracking safety over about 13 weeks.
West Haven, ConnecticutAges 18–80 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Phoenix, ArizonaAges 18 years+
Hear when a new Cognition trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 1,981 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.