Clinical trials
Cognitive Functioning clinical trials
Below are recruiting cognitive functioning clinical trials, each written for real people, not researchers. We’re tracking 315 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06889961Recruiting
Daily mixed spice consumption for memory health
This trial tests whether eating a mix of spices every day can help improve memory in older adults with mild memory changes. If you are between 50 and 80 and have no major health conditions, you may be able to join.
Los Angeles, CaliforniaAges 50–80 - NCT06682741Enrolling by invitation
Comparing exercise programs for brain health in women
This study tests whether different types of exercise training can improve thinking and memory in women. It may help find the best workout for keeping your mind sharp.
Poznan, PolandAges 50 years+ - NCT06524388Enrolling by invitation
Cognitive training study for older adults with diabetes
This study tests if a special computer-based brain training program can help improve thinking and memory in older adults with diabetes who are at risk for dementia. It might help keep your mind sharp as you age.
BeijingAges 60 years+ - NCT07338682RecruitingPhase 2
L-Arginine for memory in older adults
This trial tests if L-Arginine, a natural amino acid, can improve thinking and memory in adults over 60 with mild to moderate memory problems. You may join if you have no other brain diseases or certain health conditions.
CairoAges 60 years+ - NCT07243600Recruiting
Brain Training for Memory in Mild Cognitive Impairment
This study tests a computer-based brain-training program designed to improve memory and thinking skills in older adults with mild cognitive impairment (MCI). It aims to see if these exercises can help keep the brain healthy and slow down memory decline.
Montreal, QuebecAges 65 years+ - NCT06871293Recruiting
Long Covid recovery: rehab with coaching
This study tests a program of rehab exercises and memory/thinking activities, along with coaching messages, to help people with Long Covid feel better and function in daily life. You may qualify if you had Covid, have high blood pressure or diabetes, and still have symptoms like fatigue or trouble thinking for at least 4 weeks.
Bogotá, Bogotá DCAges 18–80 - NCT05449119Recruiting
Study links gut health, diet, and thinking and movement in seniors
This study looks at how differences in gut bacteria and nutrition may relate to changes in thinking and movement in people over 75 who have a reduced appetite (“small eaters”). It may help doctors better understand what could be contributing to these problems and how nutrition might play a role.
DijonAges 75 years+ - NCT06429774Recruiting
Comparing hospital treatments for traumatic brain injury
This study compares how well different hospital teams work together to treat people with traumatic brain injury. It aims to find the best care approach to help patients recover.
Beijing, Beijing MunicipalityAges 1–89 - NCT07457138Recruiting
Brain health study for people with memory worries
This study looks at people who are worried about their memory or thinking skills, even if tests show no problems. It aims to understand brain health over time in a Lombardy clinic.
Costa Masnaga, LombardyAges 18 years+ - NCT04297020Recruiting
Checking brain health in breast cancer survivors
This study looks at differences in brain function in people who have had breast cancer, compared with certain people without that history. It’s testing how brain health changes after breast cancer and relates to mood, thinking, and daily functioning.
Los Angeles, CaliforniaAges 35–65 - NCT05790707Recruiting
Ablation for persistent atrial fibrillation to help memory
This study checks whether a procedure called atrial fibrillation ablation can slow memory problems in people who already have mild cognitive impairment. Participants will be tested on thinking and memory before and after treatment to see if the procedure helps.
AngersAges 60–80 - NCT06512922Enrolling by invitation
Cognitive training for older adults with high blood pressure
This trial tests whether a special computer-based brain training program can help older adults with high blood pressure think more clearly. It is done in your local community and aims to find a way to keep your mind sharp as you age.
Beijing, ShijingshanAges 60 years+ - NCT07283276Recruiting
Core training vs cognitive training for ankle instability
This study tests whether special core exercises or mental training can help improve your balance and control after repeated ankle sprains. If you have chronic ankle instability, this could help you find which type of training works best.
CairoAges 18–30 - NCT07358598Recruiting
Eye movement and thinking in older adults
This study looks at how eye movements relate to thinking abilities in people aged 65 and older. It may help understand how the brain changes with age.
Kaohsiung CityAges 65 years+ - NCT06434168Enrolling by invitation
Yoga for brain health in heart failure
This study tests whether yoga can help improve memory and thinking for people with heart failure who also have mild memory problems. It aims to see if a gentle yoga program can support both heart and brain health.
Auburn, AlabamaAges 55–70 - NCT05556655Recruiting
Brain stimulation and how it changes memory task performance
This study tests how a brain stimulation method affects how well you do thinking and memory tasks. You would complete cognitive testing before and after the stimulation, and the researchers look at whether your performance changes.
Fort Collins, ColoradoAges 18–65 - NCT06728774Recruiting
Cognitive rehab for veterans with depression and memory problems
This trial tests a cognitive rehabilitation program for veterans who have depression (MDD) and are experiencing trouble with memory, attention, or thinking. The goal is to see if the program can improve these cognitive issues.
Portland, OregonAges 18 years+ - NCT06215274Recruiting
Leisure activities and early Alzheimer's study
This trial looks at how engaging in mentally stimulating leisure activities (like puzzles, reading, or games) may affect brain health in people with early memory concerns. Researchers want to understand the brain changes that happen with these activities.
Fuzhou, FujianAges 60 years+ - NCT07220694Recruiting
Sabroxy supplement for memory and insulin resistance
This study tests whether a supplement called Sabroxy can improve insulin resistance and memory in adults with mild cognitive impairment and insulin resistance. It may help if you have early memory problems and your blood sugar is slightly higher than normal.
San Francisco, CaliforniaAges 40–80 - NCT07760545Recruiting
Memory screening by video before surgery
This study tests whether doing a quick memory and thinking check over video call is as reliable as doing it in person. You would take part before your scheduled surgery to help improve how cognitive health is assessed.
Vancouver, British ColumbiaAges 65 years+ - NCT07786532Recruiting
Sports-based cognitive therapy for children's attention and memory
This study tests a sports-based cognitive therapy program for children aged 8-12 with mild attention or behavioral issues. It aims to improve their attention and memory through structured sports activities.
Chak Six Hundred Twenty-four, KpkAges 8–12 - NCT06753578Recruiting
Cognitive training for seniors with mild memory loss
This trial tests a new cognitive training program designed to improve quality of life and thinking skills in older adults living in care facilities who have mild cognitive impairment (MCI). The program uses acceptance and commitment therapy (ACT) to help participants adapt to memory challenges.
Santander, CantabriaAges 65 years+ - NCT07713641Recruiting
Testing gut bacteria's effect on brain function and inflammation
This trial looks at whether short-chain fatty acids (substances made by gut bacteria) can reduce inflammation and improve thinking skills (executive function). You'll receive an injection that causes mild, temporary inflammation (like a bad cold) and complete cognitive tasks.
LeuvenAges 18–45 - NCT07641335Recruiting
Caffeine's Effects on Chess Playing and Thinking Skills
This study tests whether caffeine helps professional chess players think more clearly and play better. Researchers will measure your chess performance and mental focus after you take caffeine or a placebo.
St Louis, MissouriAges 18–50
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Common questions
- Are there clinical trials for cognitive functioning?
- Yes. Clin2 currently lists 315 recruiting cognitive functioning studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive functioning trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive functioning trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.