Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05563259Enrolling by invitation
Brain and memory testing in fatty liver disease
This study checks how well your brain and memory work in people with non-alcoholic fatty liver disease. It also looks at brain function with special assessments, which may help researchers understand what changes happen with this condition.
Nanjing, JiangsuAges 20–75 - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT04297020Recruiting
Checking brain health in breast cancer survivors
This study looks at differences in brain function in people who have had breast cancer, compared with certain people without that history. It’s testing how brain health changes after breast cancer and relates to mood, thinking, and daily functioning.
Los Angeles, CaliforniaAges 35–65 - NCT05998031Recruiting
Testing brain stimulation for memory in mild memory loss
This study tests if a gentle brain stimulation technique called tDCS, combined with memory training, can help older adults with mild cognitive impairment (MCI) improve their working memory. You'll have MRI scans and attend training sessions.
Gainesville, FloridaAges 60–95 - NCT06312956Recruiting
Sleep Apnea and Ventilotherapy: A Study Before and After Treatment
This trial studies how sleep apnea affects the body and brain before and after starting treatment with a breathing device (ventilotherapy). It aims to understand the benefits of early treatment for people with obstructive sleep apnea.
Piancavallo, VCOAges 20–60 - NCT06452147Recruiting
Anesthesia and brain health after hip surgery in older adults
This trial is testing different types of anesthesia to see how they affect brain function (memory, thinking) after hip fracture surgery in older adults. It aims to find the safest approach for elderly patients.
Wenzhou, ZhejiangAges 65 years+ - NCT07526740Recruiting
Brain Stimulation and Training for Mild Memory Loss
This study tests whether combining brain stimulation (TMS) with cognitive training games can help people with mild cognitive impairment—early memory and thinking problems. The goal is to see if this combination improves thinking abilities and slows cognitive decline.
Charleston, South CarolinaAges 60–85 - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05791994Recruiting
Study tests visual stimulation to improve attention in mild memory issues
This study looks at whether repeated visual stimulation exercises can improve attention in people age 60+ with a specific type of mild cognitive impairment. A study team will also want you to have an informal caregiver to support participation.
AngersAges 60 years+ - NCT06539403Recruiting
Thinking about memory and confidence with age
This study asks people who have been referred to a memory clinic about how they feel about their memory and memory changes with age. It aims to understand how confident you are in your memory and how that might shift over time.
LondonAges 65–120 - NCT06561906Recruiting
Early Alzheimer's detection using scans, genetics and blood
This study uses brain scans, blood tests, and genetic information to find early signs of Alzheimer's disease before memory problems start. It aims to predict who might develop Alzheimer's in the future.
Nanjing, JiangsuAges 50–79 - NCT07347574Recruiting
Early Alzheimer's detection study in Hong Kong communities
This study aims to find early signs of Alzheimer's in the community through blood tests and assessments. It's for people who can think clearly and agree to participate without major health issues.
Hong KongAges 60–75 - NCT07629349Recruiting
Understanding Lewy Body Dementia Symptoms and Progression
This study follows people with dementia with Lewy bodies to understand how the disease develops and changes over time. Researchers will track your symptoms and use blood tests and brain imaging to learn more about what causes this type of dementia.
StockholmAges Any age - NCT04240665Enrolling by invitation
Test a digital notebook for memory problems
This study tests a digital “memory notebook” to help people who have early memory concerns keep track and report changes over time. It may be useful if you’re having mild memory issues and can complete surveys with a study partner.
Sacramento, CaliforniaAges 60 years+ - NCT07212504Recruiting
Brain stimulation to improve memory in older adults with mild memory problems
This study tests a new type of brain stimulation called accelerated neuromodulation, aimed at improving memory and thinking in older adults with mild memory issues. It uses magnetic pulses to gently stimulate a part of the brain linked to memory.
Toronto, OntarioAges 55–85 - NCT07304674Recruiting
Primary Aldosteronism and Thinking Ability Study
This study looks at whether primary aldosteronism (a treatable cause of high blood pressure) is linked to memory and thinking problems. It may help understand if managing this condition can protect brain health.
Chengdu, SichuanAges 40 years+ - NCT05770479Enrolling by invitation
Testing long-lasting cognitive training for older veterans
This study looks at whether a cognitive training program you’ve already completed can keep helping over time, and whether it can be improved with “booster” sessions. It may help older veterans maintain thinking and daily functioning skills after earlier training.
San Diego, CaliforniaAges 55 years+ - NCT05294068Recruiting
Study barriers to physical activity in aging with disabilities
This study looks at what makes it hard or easier for people with cognitive, physical movement, or sensory (hearing/vision) impairments to be active as they age. It may help improve support and services for physical activity at a rehabilitation/parasport clinic.
GarchesAges 6 years+ - NCT06238492Recruiting
Boosting brain speed after spinal cord injury
This trial tests a program to help improve how quickly your brain processes information after a recent spinal cord injury. It focuses on people who are about 6 months post-injury.
Englewood, ColoradoAges 18–59 - NCT06672367Recruiting
Balance and gaze exercises for brain health in older adults
This study looks at whether adding gaze stability exercises (eye and head movements) to balance training can improve thinking, balance, and walking steadiness in older adults with mild memory problems. It may help those who can follow simple instructions and join in physical activity.
IslamabadAges 55 years+ - NCT07560696Recruiting
Web-based therapy for thinking and speech after illness
This study tests whether patients recovering from serious illness in the ICU or stroke ward can use a web-based platform called Cognishine to help rebuild their thinking skills and speech ability. The goal is to see if this online approach works well and is practical for patients receiving support from therapists.
LiverpoolAges 18 years+ - NCT06657274Recruiting
Digital brain training for early memory problems
This study tests a smart digital program (app or computer-based) to help with memory, thinking, and daily life in people with early Parkinson's, mild cognitive impairment, or early memory concerns. It uses brain stimulation (TMS) along with cognitive exercises.
Brescia, ITAges 18–85 - NCT07213700Recruiting
Long-term study on Alzheimer's disease
This study follows people who are either being evaluated for Alzheimer's disease or have already been diagnosed. Researchers want to track their health over many years to better understand the disease and how treatments affect it.
GrazAges Any age - NCT07731191Recruiting
Digital tools to predict Alzheimer's risk factors
This study uses smartphone tools to track early signs of Alzheimer's by analyzing risk factors. It is for people with mild cognitive issues (MCI) or subjective cognitive decline (SCD) who do not have dementia.
Brescia, BSAges 18 years+
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.