Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 571 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06520878RecruitingPhase 2
Nano-PSO for memory loss in older adults
This trial tests a supplement called NANO-PSO to see if it can help thinking and memory in older adults with mild to moderate memory problems. It may be an option for people with early Alzheimer's disease.
Miguel Hidalgo, Mexico CityAges 60 years+ - NCT06928298Recruiting
A cognitive screening study for Spanish speakers aged 60+
This study tests a new, easy-to-use cognitive screening tool on an iPad for older adults who speak Spanish. It aims to help primary care doctors detect thinking or memory changes early.
Austin, TexasAges 60 years+ - NCT06853405Recruiting
Nutrition program to prevent memory decline
This study tests whether nutrition-based changes can help prevent memory loss and thinking problems in people who are at higher risk for dementia. To join, you need to be between 55 and 85, have at least 4 years of schooling, and have an elevated dementia risk score.
Porto, PortugalAges 55–85 - NCT07114458Recruiting
Delirium and Thinking Changes in Older Hospital Patients in Isolation
This study looks at how being in isolation in the hospital might affect confusion or thinking problems in older adults. You may be eligible if you are 70 or older and have been in isolation for at least 24 hours.
Hamburg, Free and Hanseatic City of HamburgAges 70 years+ - NCT07268079Recruiting
Testing a VR app for brain and thinking skills
This study is testing a virtual reality app called VIRADIA to see if it can help check brain and thinking skills. Doctors are looking for people with and without a neurological condition like Parkinson's or multiple sclerosis to take part.
Nitra, Nitra RegionAges 18–80 - NCT04123314RecruitingEarly Phase 1
Psilocybin study for depression in mild memory or early Alzheimer’s
This early-phase study tests whether psilocybin (a psychedelic substance) can help with depression in people who have mild memory problems or early Alzheimer’s. The trial also closely monitors safety, thinking changes, mood, and blood pressure before and after dosing.
Baltimore, MarylandAges 18–85 - NCT06809725Enrolling by invitation
Study of a headband device for cognitive health check
This study tests a new way to check cognitive (thinking and memory) health using a simple headband that measures electrical signals on your scalp. It is looking for people 65 to 90 years old, with or without memory concerns, and a family member or friend who can also take part.
Miami, FloridaAges 65–90 - NCT06223672Recruiting
Healthy fats for better thinking in older adults
This study tests whether healthy fats can help improve thinking and memory in people with mild memory concerns. It is for people with overweight and normal blood sugar.
Columbus, OhioAges 40–75 - NCT07284446Recruiting
Depression, memory, and outcomes in heart failure patients
This study looks at how depression and memory problems affect recovery in people hospitalized with worsening chronic heart failure. It aims to find better ways to support patients during their hospital stay.
KaunasAges 18–85 - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+ - NCT05624632Enrolling by invitation
Online cognitive tests you can do remotely
This study checks how well an online remote testing approach measures thinking and memory. It may help researchers collect cognitive data more easily, especially by combining it with other related studies.
BarcelonaAges 45–80 - NCT07109830Recruiting
Brain-computer game for thinking skills in kids
This study tests a brain-computer game that uses brain waves to measure thinking skills in kids ages 7-16 with or without movement challenges. The goal is to see if the game can help evaluate cognitive abilities in a fun way.
Edmonton, AlbertaAges 7–16 - NCT06897670Recruiting
Brain blood flow patterns in mood and memory disorders
This study uses a headband with light sensors (fNIRS) to measure blood flow in the brain while you do thinking tasks. It aims to understand differences in brain activity for people with depression, bipolar disorder, or mild memory loss.
Rochester, MinnesotaAges 18 years+ - NCT05830422Enrolling by invitation
Predicting late thinking problems after cardiac arrest
This study looks at how to predict delayed cognitive (thinking) impairment in people who survived a cardiac arrest but initially seemed neurologically okay. It may help identify who is at higher risk so follow-up and support can be planned earlier.
Daejeon, Seo-guAges 18 years+ - NCT04335994Recruiting
Home sleep testing for people with memory trouble
This study looks at how well home sleep apnea testing works for people with cognitive impairment (memory/thinking problems) to help improve outcomes. You may be asked to do a home sleep test (and possibly an in-lab test) and will involve a caregiver if needed.
Toronto, OntarioAges Any age - NCT04306432Recruiting
Check how cognitive tests change after brain tumor radiation
This trial studies how radiation therapy affects thinking and memory in adults with certain brain tumors. It may help doctors understand which patients are more likely to have cognitive side effects and how to measure them over time.
Copenhagen, Capital RegionAges 18–100 - NCT06413173Recruiting
Remote brain stimulation for attention after mild TBI
This trial tests if a remote brain stimulation device can improve attention and concentration in active-duty service members who have had a mild traumatic brain injury. Participants use the device at home while completing tasks to help with daily focus.
San Diego, CaliforniaAges 18–60 - NCT06640673Recruiting
Brain Wave Study for Mild Memory Problems and Parkinson's Disease
This study uses a special brain wave test (high-density EEG) to learn more about mild memory problems and how they might be linked to Parkinson's disease. If you join, you'll help researchers understand brain activity patterns that could lead to better diagnosis and care.
Lido, ItalyAges 50–90 - NCT07496359Recruiting
Helping older adults with diabetes and memory concerns
This study tests a program that helps older adults with both diabetes and early memory problems, along with their caregivers, manage their health better together.
Hong KongAges 55 years+ - NCT04897334Recruiting
Brain stimulation plus rehab to improve thinking after stroke
This study tests whether a noninvasive brain stimulation treatment, combined with rehabilitation, can improve thinking and other “neurocognition” problems after a recent stroke. It may help people whose thinking has been affected by stroke within the past month.
Philadelphia, PennsylvaniaAges 18–90 - NCT07508215Recruiting
Bright light therapy for memory problems in depression
This study tests whether daily bright light therapy can improve thinking and memory in people with major depression. You would continue your regular antidepressant and add 30-60 minutes of light box use each morning.
Beijing, Beijing MunicipalityAges 18–60 - NCT07523113Recruiting
Brain Fog Treatment for ME/CFS Using Cognitive Training
This study tests whether a computerized cognitive training program combined with a mild electrical nerve stimulation device (worn on the ear) can help improve thinking and memory problems in people with ME/CFS. The goal is to see if this approach helps with brain fog and daily functioning.
Birmingham, AlabamaAges 18 years+ - NCT07802392Recruiting
Virtual nature program for older adults with memory problems
This study tests a virtual reality nature program designed to improve wellbeing in older adults with mild to moderate memory problems. If you enjoy nature and can use a virtual reality headset, this program might be a relaxing and enjoyable addition to your routine.
Terrassa, BarcelonaAges 65 years+ - NCT06312956Recruiting
Sleep Apnea and Ventilotherapy: A Study Before and After Treatment
This trial studies how sleep apnea affects the body and brain before and after starting treatment with a breathing device (ventilotherapy). It aims to understand the benefits of early treatment for people with obstructive sleep apnea.
Piancavallo, VCOAges 20–60
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 571 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.