Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 568 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07404085Recruiting
Boosting thinking skills with training and medication in mood or schizophrenia disorders
This study tests whether adding a medication that may improve brain flexibility makes memory and thinking training work better for people with bipolar disorder, recurring depression, or schizophrenia spectrum disorders. It could help improve daily thinking skills and quality of life.
Frederiksberg, Capital Region of DenmarkAges 35–75 - NCT05907265Recruiting
Virtual reality sessions to improve thinking after chemotherapy
This study tests whether immersive virtual reality training can improve thinking and concentration in adults who have had ongoing thinking problems after chemotherapy. It may help by using guided VR tasks that aim to support cognitive skills during recovery.
TerrassaAges 18–65 - NCT07383311Recruiting
Natural supplements for memory and sleep
This study tests whether certain natural compounds (autophagy enhancers) can improve sleep in people with age-related memory concerns, including those with mild cognitive impairment and those with only subjective declines.
Greifswald, Mecklenburg-VorpommernAges 55–75 - NCT06962722Recruiting
Arm training to boost thinking in healthy older adults
This study tests whether a gentle arm movement training program can help keep your thinking skills sharp as you age. It's for healthy older adults who have no memory, heart, or other major health problems.
Derby, DerbyshireAges 65–85 - NCT06024473Recruiting
Brain stimulation and virtual reality for memory loss
This study uses a combination of brain stimulation (rTMS) and virtual reality exercises to help improve memory and thinking. It is for people aged 55 and older who have Mild Cognitive Impairment (MCI), a condition that can affect memory but is not dementia.
Little Rock, ArkansasAges 55 years+ - NCT04114994Recruiting
Memory testing study for adults 50 and older
This study checks how people’s thinking and memory change over time using a specific cognitive test. It may help researchers understand patterns of memory change and supports future research on brain health.
Miami, FloridaAges 50 years+ - NCT07496255Recruiting
Virtual reality for memory help after ICU confusion
This trial tests whether using virtual reality (VR) can help older adults recover their thinking and memory after a serious illness and confusion in the ICU. You may be eligible if you are 50 or older, spent time on a breathing machine, and had delirium in the ICU.
Indianapolis, IndianaAges 50 years+ - NCT03094026Recruiting
Practice cognitive training after a transplant
This study tests whether a structured cognitive training program can help people think and remember better after an allogeneic stem cell transplant. It may also explore how people feel about genetics and genetic testing.
Birmingham, AlabamaAges 21 years+ - NCT03836950RecruitingPhase 1/Phase 2
Brain stimulation to improve thinking in Parkinson’s
This trial studies a noninvasive treatment called rTMS to help improve thinking and memory in people with Parkinson’s who have mild cognitive problems. It may help strengthen brain function, but it also has strict safety and eligibility rules to protect against seizure and metal-related risks.
Chicago, IllinoisAges 50 years+ - NCT07128186Recruiting
AI predicts memory decline in type 2 diabetes
This study uses an AI tool to predict memory problems in people with type 2 diabetes. It may help catch early signs of cognitive decline and guide future care.
Enshi, HubeiAges 40–75 - NCT07114809Recruiting
Can brain stimulation and virtual reality boost thinking in MS?
This study tests whether a combination of gentle brain stimulation (tDCS) and virtual reality exercises can improve memory and thinking problems in people with multiple sclerosis. If you have mild to moderate disability and no major health issues, you may be able to join.
Genova, ItalyAges 18–65 - NCT07041450Recruiting
Screening for Alzheimer's treatment using digital tests and blood tests
This study is testing whether simple digital memory tests and blood tests can help find people who might qualify for anti-amyloid treatments (medications that target Alzheimer's-related proteins). It aims to make screening easier and faster, without needing a spinal tap or PET scan.
Greenfield Park, QuebecAges 55–90 - NCT06986096Recruiting
Brain health through diet and exercise
This study tests whether a healthy lifestyle program—combining nutrition advice and exercise training—can help protect brain health in people with early memory problems. It may be a good fit if you have mild cognitive concerns and are ready to make positive changes.
Bratislava, Bratislava RegionAges 60–80 - NCT06316557Recruiting
TMS for memory and thinking after stroke
This trial tests if a gentle brain stimulation treatment (TMS) can help improve memory and thinking after a recent stroke. It is for people who had their first stroke within the last two weeks and have mild cognitive difficulties.
BeijingAges 18 years+ - NCT03372317Recruiting
Tau brain PET imaging study for adults ages 55–90
This study uses a brain scan called PET to look at tau (a brain protein) and how it relates to thinking and memory. It may help researchers understand early brain changes, though it’s mainly for healthy people living near Columbia who have had an amyloid PET scan before.
New York, New YorkAges 55–90 - NCT07842029Recruiting
Blood tests and thinking checks for memory clinic patients
This study is for people on a memory clinic waiting list. It uses a simple blood test and remote thinking exercises to help doctors understand memory problems better and improve care.
London, Greater LondonAges 50 years+ - NCT06408103Recruiting
Brain health program for you and your caregiver
This study tests a program that combines exercise, nutrition, and mental activities for both you and your family caregiver. It aims to help keep your thinking and memory skills strong.
Bucaramanga, Santander DepartmentAges 55 years+ - NCT06753578Recruiting
Cognitive training for seniors with mild memory loss
This trial tests a new cognitive training program designed to improve quality of life and thinking skills in older adults living in care facilities who have mild cognitive impairment (MCI). The program uses acceptance and commitment therapy (ACT) to help participants adapt to memory challenges.
Santander, CantabriaAges 65 years+ - NCT05785156Recruiting
Quick test study to predict stroke and memory disease outlook
This study tests quick new methods to measure “slowed actions” in people with stroke or memory-related brain conditions. The goal is to see whether these quick tests can help predict future outcomes and guide care.
AmiensAges 40–85 - NCT06686563Enrolling by invitation
Sights & sounds for better health in older adults
This trial studies whether using light and sound patterns can improve thinking, mood, and physical health in older adults. It aims to find a simple, non-drug way to boost well-being.
Gandra, ParedesAges 18–100 - NCT06518824Recruiting
Theta brain stimulation to boost thinking in Parkinson's
This study tests whether a special pattern of deep brain stimulation (called theta bursts) can improve thinking and memory in people with Parkinson's disease. It's for patients who already have a DBS device in their brain that is at least 3 months old.
Vancouver, British ColumbiaAges 18–80 - NCT06407141Enrolling by invitation
Brain stimulation study for older adults with mild memory loss
This trial tests whether a harmless brain stimulation technique called TPS can improve memory and thinking in older adults with mild memory problems. You may be able to join if you have MCI, are right-handed, and are generally healthy otherwise.
Hong KongAges 50–100 - NCT06027554RecruitingPhase 2
MitoQ for frailty, walking, memory, and blood flow in older adults
This trial tests whether a supplement called MitoQ can improve blood vessel health, walking speed, and thinking skills in older adults who are frail or have mild memory problems. It aims to see if MitoQ helps maintain independence and quality of life.
Farmington, ConnecticutAges 65–80 - NCT05460143Recruiting
Optical brain scanning to study memory and thinking
This study uses brain “optical” and possibly MRI scans to understand how thinking and memory work in people with Lewy body dementia, Alzheimer’s disease, or mild memory problems. It may help researchers find better ways to measure brain changes and cognition over time.
CambridgeAges 18 years+
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 568 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.