Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 575 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06995443Recruiting
Can light therapy help 'chemo brain' after breast cancer?
This study tests whether a special light therapy (photobiomodulation) can help improve the 'chemo brain' – memory and thinking problems – that some women experience after breast cancer chemotherapy. If you've had memory issues since chemo and finished treatment within the past year, you may be able to join.
ValenciennesAges Any age - NCT07002996Recruiting
Virtual reality memory training for mild cognitive impairment
This study tests whether a special memory training program using virtual reality can improve thinking skills in people with mild cognitive impairment. It may help slow memory loss and keep your mind sharper.
Verdun, QuebecAges 55 years+ - NCT07064226Recruiting
Digital cognitive rehab for older adults
This trial tests a digital program designed to help improve cognitive skills in older adults with mild memory or thinking problems. The program may help strengthen attention, memory, and problem-solving abilities.
MilanAges 65 years+ - NCT06682741Enrolling by invitation
Comparing exercise programs for brain health in women
This study tests whether different types of exercise training can improve thinking and memory in women. It may help find the best workout for keeping your mind sharp.
Poznan, PolandAges 50 years+ - NCT07594665Enrolling by invitation
Home-based cognitive health blood tests for older adults
This study invites people aged 65+ who are already part of the SHUTi MIND research program to do simple blood tests at home to check for early signs of cognitive changes. The goal is to make it easier for people to access brain-health testing without going to a clinic.
Charlottesville, VirginiaAges 65 years+ - NCT05149742Recruiting
Study of hearing loss and thinking skills in midlife adults
This study looks at how severe hearing loss affects thinking and memory in adults aged 45–64. Researchers will compare people with significant hearing loss to people with normal hearing who are similar in age, sex, and education.
ParisAges 45–64 - NCT06793735Recruiting
Virtual reality app for memory and thinking problems
This trial tests a virtual reality app you can use at home to help with early memory or thinking problems. It may be an option if you have mild cognitive impairment or notice your thinking is slowing down.
Messina, ItalyAges 40–80 - NCT06335836Recruiting
Social connections and brain health in memory decline
This study looks at how being socially isolated or socially active affects memory and brain health in people who feel their thinking is getting worse. You may join if you notice a slow decline in memory or thinking, but otherwise have normal test results.
Nanjing, China, JiangsuAges 45–85 - NCT06839079Recruiting
Brain training for trauma survivors with head injury
This study tests a cognitive rehabilitation program for people with traumatic brain injury who have also experienced war, violence, or other trauma. It aims to improve memory and thinking skills using exercises and strategies.
Boston, MassachusettsAges 18–65 - NCT06993207Recruiting
Home brain monitoring study for cognitive decline
This study uses a special EEG headband to monitor brain activity at home in older adults. It aims to understand cognitive decline, including Alzheimer's and mild memory problems, and compare results with healthy volunteers.
Zaragoza, ZaragozaAges 60 years+ - NCT07404085Recruiting
Cognitive training with medication for mood disorders
This trial tests if a medication can boost the effects of cognitive training in people with bipolar disorder or recurrent depression who have memory or thinking problems. It aims to improve daily functioning.
Frederiksberg, Capital Region of DenmarkAges 40–75 - NCT05885295Recruiting
Testing thinking and memory after stroke using cognitive exams
This study looks at how thinking and memory change after a stroke using short cognitive tests. It may help researchers better understand which brain changes affect thinking, and how to measure them accurately.
LondonAges 18 years+ - NCT03025334Recruiting
Brain stimulation study for thinking changes in Parkinson’s
This study tests whether a non-invasive brain stimulation approach (tDCS) can improve thinking and memory in people with Parkinson’s disease. You may be invited because your Parkinson’s is typical and your memory testing shows you do not have dementia.
Winnipeg, ManitobaAges 40 years+ - NCT04601038RecruitingPhase 2
Testing a stress-blocking drug for early Alzheimer's risk
This study tests a new medication, CORT108297, that may help protect the brain from the harmful effects of stress in people at risk for Alzheimer's disease. It is looking for adults age 55 and older who either have mild memory problems or are healthy but have a family history, APOE4 gene, or memory concerns.
Baltimore, MarylandAges 55 years+ - NCT06589544Recruiting
Virtual reality and brain stimulation for depression in cancer patients
This trial tests whether combining virtual reality therapy with transcranial magnetic stimulation (a non-invasive brain treatment) can help reduce depression in people who have had cancer in the last 5 years. It aims to improve mood without using medication.
Ferrara, FEAges 18–100 - NCT07485387Recruiting
Korean cognitive aging study using smartphone app
This study looks at how thinking and memory change as people get older. It uses a smartphone app to track these changes over time in healthy older adults living in South Korea.
Seoul, Select One...Ages 60 years+ - NCT07273175Enrolling by invitation
Can brain stimulation improve thinking in schizophrenia?
This study tests if a safe, non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can help improve cognitive functions like memory and attention in people with schizophrenia. If you are between 18 and 65, have a schizophrenia diagnosis, and are mentally stable, you may be eligible.
Lodz, Łódź VoivodeshipAges 18–65 - NCT06973018Enrolling by invitation
Online cognitive rehab for mild memory problems
This trial tests an online program to help people with mild to moderate cognitive problems after a brain injury or nervous system disease improve their thinking skills. It is for Swedish speakers with internet access.
Stockholm, Stockholm CountyAges 18 years+ - NCT04701177Enrolling by invitation
Smartphone-based study of brain biomarkers in memory clinic patients
This observational study follows people with (or at risk for) Alzheimer’s-related brain changes and a comparison group without them. It uses clinic visits, cognitive testing, questionnaires, and possibly a spinal fluid test to better understand brain biomarkers and how they relate to thinking and daily life.
Corfu, CorfuAges 45 years+ - NCT02290834Recruiting
Studying brain and thinking changes after chemotherapy in older breast cancer patients
This study looks at how chemotherapy may affect memory and thinking, using thinking tests and possibly brain imaging. It compares older breast cancer patients who do and do not get chemotherapy, plus a group of healthy older adults.
Boston, MassachusettsAges 60 years+ - NCT03653156Recruiting
Aging and brain study for mild memory loss and dementia
This study checks how age affects memory and thinking, and compares people with mild memory problems, Alzheimer’s disease types, vascular dementia, and healthy controls. You may help researchers understand brain changes using thinking tests, MRI scans, and blood or spinal fluid tests.
Hefei, AnhuiAges 18 years+ - NCT05653141Recruiting
Study for thinking problems after a first stroke
This trial looks at treatments or approaches to improve thinking and memory problems after a first stroke. You may be eligible if your stroke was in the front part of the brain, confirmed by MRI, and you enroll within 10 days.
BernAges 18 years+ - NCT05915000Recruiting
CSF protein tests to predict shunt response in hydrocephalus
This study looks at fluid-based “CSF” protein markers to predict how well a brain shunt works in adults with chronic hydrocephalus (fluid buildup). If you qualify, your CSF sample may help doctors better estimate your likely response to treatment.
Valencia, ValenciaAges 18 years+ - NCT06107842Recruiting
Exercise program for older veterans' memory and thinking
This study tests whether an exercise program called Gerofit can help improve memory and thinking in older Veterans. If you join, you will take part in supervised exercise sessions to see how it affects your brain health.
West Los Angeles, CaliforniaAges 65 years+
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 575 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.