Clinical trials
Cognitive Symptom clinical trials
Below are recruiting cognitive symptom clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07136415RecruitingPhase 4
Comparing digital therapy, trazodone, and daridorexant for menopause insomnia
This trial tests three different treatments for insomnia that started or got worse during the menopausal transition. One is a digital therapy app, and the others are two different medications. The goal is to see which works best for women aged 40–62 who are in the early stages of menopause.
Boston, MassachusettsAges 40–62 - NCT05160688Enrolling by invitation
Study of brain and mood changes when stopping cannabis
This study looks at how thinking (cognition) and psychiatric symptoms (mood/mental health symptoms) change during a period without cannabis. It uses special matched twin pairs to compare changes after stopping.
Aurora, ColoradoAges 31–47 - NCT06975280Recruiting
PTSD therapy for unaccompanied refugee teens in Greece
This study tests a talking therapy (Trauma-Focused Cognitive Behavioral Therapy) to help unaccompanied refugee minors aged 15-18 who have PTSD or stress symptoms from trauma. It aims to see if the therapy reduces distress and helps them feel better.
AthensAges 15–18 - NCT07234357Recruiting
Scent therapy for mood and behavior in early dementia
This trial uses pleasant scents (aromatherapy) to see if they can improve mood and behavior for people with early memory loss. It is designed for individuals who have a caregiver who can help them participate.
SingaporeAges 50–99 - NCT05851950Recruiting
Group CBT to reduce rumination in psychosis
This trial tests a structured group therapy (rumination-focused CBT) to help reduce repetitive negative thinking (“rumination”) that can worsen symptoms in people with psychosis. It may help you feel less stuck in unhelpful thoughts and improve day-to-day functioning while you continue your usual care.
CopenhagenAges 18–37 - NCT06538311RecruitingEarly Phase 1
TMS treatment for early Alzheimer's disease
This study tests whether a non-invasive brain stimulation treatment called TMS (transcranial magnetic stimulation) can help people with early Alzheimer's disease or related memory problems. It's a safe, gentle way to stimulate brain cells using magnetic pulses.
Boston, MassachusettsAges 40–99 - NCT06786832Recruiting
Trial for fatigued patients in primary care
This trial studies severe fatigue that started at a specific time and is not due to another illness. It aims to find better ways to diagnose, treat, and support people with long-term fatigue in primary care.
Stockholm, GustavsbergAges 18–67 - NCT06930560Recruiting
Hearing aids for dementia with mood or behavior issues
This study tests whether providing hearing aids to older adults with Alzheimer's or related dementias can reduce troubling symptoms like agitation or depression. If you have untreated hearing loss and a caregiver who can join you, this trial may help improve quality of life.
Baltimore, MarylandAges 60–100 - NCT07462013Recruiting
Lifestyle changes to prevent memory loss with depression
This study tests if healthy lifestyle changes can protect memory and thinking skills in people with depression who have no or mild memory problems.
Taichung, TaichungAges 50–80 - NCT06456931Recruiting
Buddhist vs. secular mindfulness for lingering depression
This study compares two types of mindfulness training for people with lingering depression symptoms (not fully recovered). One uses traditional Buddhist meditation, the other uses a common secular approach. It aims to see which helps reduce residual depression better.
Ragama, GampahaAges 18 years+ - NCT05699525Recruiting
Personalized app for cognitive behavioral therapy for young adults
This trial tests a mobile app that delivers personalized cognitive behavioral therapy (a structured talk-therapy approach that helps change unhelpful thoughts and behaviors). It may help reduce symptoms of anxiety, depression, or bipolar disorder for people who fit the study’s timing and safety requirements.
New York, New YorkAges 18–25 - NCT06428006RecruitingPhase 2
Sleep therapy for insomnia in multiple sclerosis
This study tests whether a talking therapy (cognitive behavioral therapy for insomnia) can help people with multiple sclerosis who have trouble sleeping. It is done online, so you can join from home.
Kansas City, KansasAges 18–65 - NCT06658041Recruiting
A step-by-step program for mild to moderate depression
This trial tests a structured support program for adults with mild to moderate depression. It uses a team-based approach in primary care to help you feel better step by step.
Hong Kong, HONG KONGAges 45–59 - NCT06631781Recruiting
Study on thinking skills in older adults with depressive symptoms
This study tests whether a tablet-based program can help older adults with depressive symptoms improve their thinking and control skills. If you have low mood and are comfortable with a tablet, you may be able to join.
JerusalemAges 65 years+ - NCT07740967Recruiting
Collagen and omega supplements for middle-aged women
This study tests whether daily collagen and omega-3 supplements can improve health in healthy middle-aged women. You would take the supplements for a period and have your health measured.
LoughboroughAges 35–65 - NCT06778096Recruiting
Online therapy for anxiety and depression in new moms
This trial tests an online therapy program for new moms who feel anxious or depressed. It uses cognitive-behavioral therapy (CBT) through a computer or tablet to help you manage your mood.
Châteauguay, QuebecAges 18 years+ - NCT06831838Recruiting
Pain management program for breast cancer survivors with joint pain
This trial tests a cognitive behavioral therapy (CBT) based program to help relieve joint and muscle pain caused by aromatase inhibitors, a common hormone therapy for breast cancer. It aims to improve your quality of life and reduce symptoms.
Jacksonville, FloridaAges 18 years+ - NCT07499570Recruiting
Talk therapy using AI for older adults with memory issues
This study tests an AI-powered talk therapy for older adults with mild memory problems who live at home. It aims to reduce challenging behaviors like agitation, anxiety, or depression by delivering personalized support through a computer or tablet.
Indianapolis, IndianaAges 65 years+ - NCT06633263Enrolling by invitation
Combined therapy for depression and insomnia
This trial tests a combination of two behavioral therapies to improve both depression symptoms and sleep problems. It may help you if you have moderate depression and insomnia and can participate in French-language sessions.
LiègeAges 18–67 - NCT06788119Recruiting
Smartphone tool for facing fears in anxiety
This study tests a smartphone tool called SYMPTOMS-JIT to help people with anxiety disorders face their fears in real life. It might be a good option if you have a specific phobia, agoraphobia, panic disorder, or social phobia and want to try a new, guided approach.
Castellon, CastellónAges 18 years+ - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT06956417Recruiting
Memory rehab after concussion
This trial tests a memory rehabilitation program for people who have had a concussion and still have memory problems. It uses a computer, tablet, or smartphone to help improve memory.
Calgary, AlbertaAges 18–59 - NCT07629349Recruiting
Understanding Lewy Body Dementia Symptoms and Progression
This study follows people with dementia with Lewy bodies to understand how the disease develops and changes over time. Researchers will track your symptoms and use blood tests and brain imaging to learn more about what causes this type of dementia.
StockholmAges Any age - NCT05821634Enrolling by invitation
Personalized telehealth counseling for anxiety and alcohol use
This study personalizes how telehealth counseling is delivered for people dealing with anxiety or trauma-related symptoms and alcohol use problems. It may help by tailoring counseling timing and approach to what you need.
Piscataway, New JerseyAges 18–65
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Common questions
- Are there clinical trials for cognitive symptom?
- Yes. Clin2 currently lists 91 recruiting cognitive symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.