Clinical trials
Cognitive Symptom clinical trials
Below are recruiting cognitive symptom clinical trials, each written for real people, not researchers. We’re tracking 91 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07207239Enrolling by invitation
Brain stimulation for treatment-resistant depression
This trial is testing a type of brain stimulation therapy called theta-burst rTMS to see if it helps with depression that hasn't improved with standard treatments. It also uses brain scans to predict who might respond best.
Budapest, Pest CountyAges 18 years+ - NCT04935619Recruiting
Testing cannabis abstinence effects in depression symptoms
This study looks at how stopping cannabis for a period of time may affect depression symptoms and thinking/memory. You might benefit by getting close monitoring of mood and cognition while researchers compare changes during cannabis abstinence.
Toronto, OntarioAges 18–55 - NCT07420426Recruiting
Smartphone therapy for memory and mood problems
This trial tests a therapy program delivered by text or voice message on your smartphone. It's designed to help people with mild memory problems manage mood or behavior changes.
Hong KongAges 50 years+ - NCT07332624Enrolling by invitation
Therapy via text for mild memory problems and mood changes
This study tests if acceptance and commitment therapy (ACT) delivered through instant messaging can help older adults with mild memory issues manage emotional or behavioral symptoms like anxiety, depression, or agitation.
Hong KongAges 50 years+ - NCT07009223Recruiting
Lifestyle changes to prevent memory issues in depression
This study tests whether healthy lifestyle changes—like diet, exercise, or stress management—can help prevent memory and thinking problems in people with depression. It aims to find ways to protect your brain health as you age.
BresciaAges 50–80 - NCT06668610Recruiting
Brain stimulation study for mild memory problems
This study tests a non-invasive brain stimulation technique (tDCS) combined with brain wave recording (EEG) to see if it can improve memory and thinking in people with mild cognitive impairment or early dementia.
Caserta, ItalyAges 55–85 - NCT06923423Recruiting
Cognitive processing therapy for drug use and trauma in prison
This study tests if a type of therapy called cognitive processing therapy (CPT) can help people in prison who have both a drug use problem and trauma-related stress. If you qualify, you would receive CPT and be compared to those getting usual care.
Little Rock, ArkansasAges 18 years+ - NCT07064551Recruiting
Combining medical and community support for depression
This study tests a new way of combining medical care with community support for middle-aged and older adults who have depression and are waiting for mental health services. The goal is to see if this team approach can help improve mood and well-being while you wait.
Hong KongAges 45 years+ - NCT07506460Recruiting
Support team with therapy for Black youth at risk of suicide
This trial tests whether adding a support team of trusted adults to cognitive behavioral therapy (CBT) helps Black youth who have recently had thoughts of suicide or a suicide attempt. You and a parent or guardian would be involved, and you would also name a support person (like a relative, coach, or mentor) to join the team.
Detroit, MichiganAges 12 years+ - NCT06574035Recruiting
Exercise and counseling for Black men with diabetes
This study tests whether a program combining physical activity with cognitive behavioral therapy (a type of talk therapy) helps African American men manage type 2 diabetes better. You would attend weekly exercise and counseling sessions for several months.
Ann Arbor, MichiganAges 18 years+ - NCT06740747Recruiting
Brain stimulation for schizophrenia symptoms
This study tests a new type of brain stimulation (called intermittent theta-burst stimulation) to see if it helps with symptoms like lack of motivation or trouble thinking clearly in people with schizophrenia. You will also have an MRI scan to see how the brain changes.
Hanover, Lower SaxonyAges 18–65 - NCT05621278Recruiting
School study of mental and physical well-being from kids to adults
This study follows students from middle school through high school and asks their parents and teachers questions about mental well-being and physical (body-related) health. It may help researchers understand what supports healthy development over time.
Beijing, Beijing MunicipalityAges 9–65 - NCT06882798Recruiting
New support program for Latinx teens with suicidal thoughts
This study tests a new support program for Latinx teens who have had serious thoughts about suicide or a suicide crisis in the past year. It involves working with both you and your family to find ways to help you feel safer and more supported.
Providence, Rhode IslandAges 12–18 - NCT02740634Recruiting
Brain imaging study for Alzheimer's disease
This study uses brain scans to understand Alzheimer's disease and related conditions that affect memory, language, or vision. It looks at how changes in the brain happen over time in people with these diagnoses.
Rochester, MinnesotaAges 21–80 - NCT05131035Recruiting
Trial for thinking-speed training to lower psychosis risk
This study targets problems with “processing speed,” or how fast your brain handles information, to see if it can improve social functioning and lower the risk of developing full psychosis. It’s for people who are considered at high risk for psychosis but do not already have schizophrenia.
Glen Oaks, New YorkAges 14–20 - NCT06843252Recruiting
Home-based brain stimulation for Huntington's disease symptoms
This study tests whether a gentle brain stimulation device (tDCS) used at home can help improve thinking and behavior in people with Huntington's disease. A caregiver is needed to be present during treatment and help with questionnaires.
San Antonio, TexasAges 18–85 - NCT06589544Recruiting
Virtual reality and brain stimulation for depression in cancer patients
This trial tests whether combining virtual reality therapy with transcranial magnetic stimulation (a non-invasive brain treatment) can help reduce depression in people who have had cancer in the last 5 years. It aims to improve mood without using medication.
Ferrara, FEAges 18–100 - NCT07652775Recruiting
Brain stimulation and exercise for memory and mood
This study tests whether combining rTMS (a non‑invasive brain stimulation) with aerobic exercise can improve memory, thinking, and mood in older adults who have mild memory problems and depression. It may offer a safe, drug‑free way to help both brain health and emotional well‑being.
Taipei, Taipei CityAges 65–90 - NCT04123314RecruitingEarly Phase 1
Psilocybin study for depression in mild memory or early Alzheimer’s
This early-phase study tests whether psilocybin (a psychedelic substance) can help with depression in people who have mild memory problems or early Alzheimer’s. The trial also closely monitors safety, thinking changes, mood, and blood pressure before and after dosing.
Baltimore, MarylandAges 18–85 - NCT07391540Recruiting
Internet therapy for financial stress
This trial tests an internet-based cognitive behavioral therapy (ICBT) program for people feeling mild to moderate psychological symptoms because of money worries. It aims to see if online treatment can help reduce these symptoms.
Linköping, Östergötland CountyAges 18 years+ - NCT06923683Enrolling by invitation
Social skills treatment for brain injury
This trial tests a treatment called T-ScEmo for people with brain injury who have trouble with social skills and emotions. The treatment involves you and a support person (like a partner or close friend) working together to improve social understanding and behavior.
Boekel, North BrabantAges 18–70 - NCT07402681Recruiting
Tracking change in teens after trauma with weekly therapy
This study tests a type of talk therapy (TF-CBT) for teens who have been through trauma and still have upsetting symptoms like nightmares, flashbacks, or strong anxiety. It focuses on tracking how symptoms change over time and offers weekly sessions with a supportive adult.
Zurich, Canton of ZurichAges 12–18 - NCT07729930Recruiting
Creatine supplement study for healthy middle-aged women
This study is testing a creatine supplement (a substance that may help with energy and muscle function) in healthy middle-aged women. You may join if you are between 35 and 65, a non-smoker, and have a certain activity level.
LoughboroughAges 35–65 - NCT06363981Recruiting
Brain stimulation for depression, sleep and memory problems
This study tests a non-invasive brain stimulation treatment (called rTMS) to help with depression, sleep problems, and memory or concentration issues. It's designed for people with moderate to severe depression who also have trouble sleeping and thinking clearly.
KrakowAges 18–65
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Common questions
- Are there clinical trials for cognitive symptom?
- Yes. Clin2 currently lists 91 recruiting cognitive symptom studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive symptom trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive symptom trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.