Clinical trials
Colon Cancer clinical trials
Below are recruiting colon cancer clinical trials, each written for real people, not researchers. We’re tracking 290 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04491929Recruiting
Radiation treatment for colon cancer in the liver using tiny beads
This trial studies a targeted liver radiation procedure that uses tiny radioactive beads to treat colon cancer spread mostly in the liver. It may help people whose liver tumors cannot be removed or treated with other common local treatments, but it has several safety and “screening” checks.
Aarhus N, DanmarkAges 18 years+ - NCT06200831Recruiting
Same surgery or two surgeries for colorectal cancer with liver spread
This trial compares having one surgery to remove both the colon tumor and liver tumors at the same time versus having two separate surgeries. It aims to find which approach is safer and works better for patients whose cancer has spread only to the liver.
OsloAges 18–80 - NCT04307901Recruiting
Test a capsule that checks the colon when colonoscopy isn’t finished
This trial tests whether a swallowable camera capsule can safely check the colon and find possible tumor-related issues when a standard colonoscopy can’t be completed. It may help people who can’t or don’t want another colonoscopy right away.
SvendborgAges 18 years+ - NCT02222844Recruiting
MRI checks for treatment planning in sigmoid colon cancer
This study uses MRI scans to better plan “curative” treatment (aimed at cure) for sigmoid colon cancer before surgery. It is for people who may still be deciding on the radical (major, curative) treatment plan and who can safely have an MRI.
Huntingdon, CambridgeshireAges 16 years+ - NCT06972160Recruiting
Boosting colorectal cancer screening in Barcelos/Esposende
This study looks at ways to help more people get screened for colorectal cancer. If you're between 50 and 74 and haven't had certain screenings recently, you may be able to join.
PortoAges 49–75 - NCT07213193Recruiting
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RomaAges 18 years+ - NCT07153458Recruiting
Finding new markers for colorectal cancer
This trial is looking for new, non-invasive markers to help detect and predict colorectal cancer. Researchers will study people with colorectal cancer, those with precancerous growths, and healthy people to find better ways to diagnose the disease.
Castellana GrotteAges 18 years+ - NCT07033156Recruiting
Colorectal cancer detection using gene methylation test
This study is testing a new way to detect colorectal cancer early by looking for specific changes (gene methylation) in stool and blood samples. If you are 40 or older and have a colonoscopy scheduled, this non-invasive approach might help find cancer sooner.
Hangzhou, ZhejiangAges 40 years+ - NCT06886282Recruiting
How colon cancer and kidney disease are linked: a imaging and gene study
This trial uses advanced imaging and genetic tests to understand how colon cancer and chronic kidney disease may be connected. It may help decide the best treatment for people with both conditions.
NaplesAges 18 years+ - NCT06708429Recruiting
Lynch syndrome and gut immune system study
This study looks at how the immune system interacts with the gut lining in people with Lynch syndrome and those without. It may help us better understand how Lynch syndrome affects the body.
Monrovia, CaliforniaAges 18 years+ - NCT06057350Recruiting
Surgery versus endoscopy for early colon cancer with uncertain margins
This trial compares surgery versus an endoscopic procedure for people who had a colon polyp removed but some cancer cells may still be present at the edges. The goal is to see which approach leads to better outcomes and fewer side effects for early-stage colon cancer.
Oslo, AkershusAges 40 years+ - NCT05755672Recruiting
Study biomarkers during curative-intent treatment for metastatic colon cancer
This study looks at biological markers (substances measured in the body) during treatment for metastatic colorectal cancer. It may help doctors better understand how treatment works, using patients who are treated with a goal of cure.
Lund, Skåne CountyAges 18–110 - NCT04450758Recruiting
Stent or stoma right away versus surgery later for bowel blockage
This trial studies treatment choices for adults with a large-bowel blockage caused by colon cancer. It compares doing an emergency procedure now (like a stent or stoma) versus bridging to a later colon surgery, to see which approach is safer and works better.
GothenburgAges 18–100 - NCT07594626RecruitingPhase 1/Phase 2
BMS-986504 and Pemetrexed for Advanced Tumors With MTAP Loss
This trial tests a new drug (BMS-986504) combined with an existing chemotherapy (pemetrexed) for advanced solid cancers that have a specific genetic change called MTAP deletion. The trial aims to see if this combination can slow or stop tumor growth in patients whose cancer has progressed despite prior treatment.
Chicago, IllinoisAges 18 years+ - NCT06887244Recruiting
Nurse phone support before colonoscopy
This trial studies whether a nurse phone call before an elective colonoscopy can improve the procedure experience, reduce anxiety, and lower financial stress.
NaplesAges 18–80 - NCT07815834RecruitingPhase 3
FAPI-guided radiation with cadonilimab and chemo for colorectal cancer spread to the abdomen
This trial tests a new combination treatment for colorectal cancer that has spread only to the lining of the abdomen (peritoneum). It combines targeted radiation, an immunotherapy drug called cadonilimab, and standard chemotherapy to see if it can help control the disease better than current options.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06997458Enrolling by invitation
Liquid biopsy study for advanced lung or colon cancer
This study is testing a simple blood draw (liquid biopsy) to track advanced lung or colon cancer. It may help doctors understand the cancer better without needing repeated tissue biopsies.
Granada, AndalusiaAges 18 years+ - NCT07361107RecruitingPhase 1
Immune response study of histotripsy in colorectal cancer
This trial tests how your body's immune system reacts to a treatment called histotripsy for colorectal cancer that has spread to the liver. Histotripsy uses sound waves to break apart tumors, and the study aims to see if this can help your immune system fight the cancer better.
New Hyde Park, New YorkAges 18 years+ - NCT04920032RecruitingPhase 1
Blood test–guided extra treatment for colon cancer recurrence risk
This Phase 1 study uses a blood test called ctDNA to decide whether and how to adjust treatment in people with colon cancer who still have a small amount of disease left after surgery. If your blood test remains positive, the trial aims to reduce recurrence risk by guiding treatment changes.
Orange, CaliforniaAges 18 years+ - NCT05365412Recruiting
Study of colon cancer in younger adults
This study looks at the clinic and lab features of colon cancer in people diagnosed at a young age. Your information from your diagnosis and treatment may help doctors understand how colon cancer differs by age.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT07790718Recruiting
Exercise program to prevent colorectal cancer after prostate radiation
This study tests whether an exercise program can help prevent colorectal cancer in men who have had pelvic radiation for prostate cancer. It involves using an iPhone app to track activity and attending exercise sessions.
Duarte, CaliforniaAges 40–80 - NCT05051046Recruiting
Screening colonoscopy with hypnosis for colorectal cancer
This trial studies whether using hypnosis during a screening colonoscopy can help people better tolerate the procedure and complete it comfortably. It’s for adults who are scheduled for a routine screening colonoscopy and meet specific safety and communication requirements.
AngersAges 18–100 - NCT00843375Recruiting
Testing stool samples to find early colon cancer and polyps
This study checks stool samples to see how well stool tests can detect early colon cancer and precancerous growths called adenomas. If you qualify, you’ll collect stool samples for a lab test (FIT) and sometimes this helps sort who should get follow-up testing.
Los Angeles, CaliforniaAges 18 years+ - NCT07878988RecruitingPhase 1
Study of LTZ-232 for advanced colorectal and other solid tumors
This study tests an experimental drug called LTZ-232 in people with advanced colorectal cancer or other solid tumors that have not responded to standard treatments. The goal is to see if it is safe and if it can shrink or slow the growth of tumors.
Scottsdale, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for colon cancer?
- Yes. Clin2 currently lists 290 recruiting colon cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colon cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colon cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.