Clinical trials
Colon Cancer clinical trials
Below are recruiting colon cancer clinical trials, each written for real people, not researchers. We’re tracking 292 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05185245Recruiting
Liver transplant for colorectal cancer spread to the liver
This study looks at whether a liver transplant can help people whose colorectal cancer has spread to the liver but cannot be removed by surgery. It also checks whether certain cancer features, treatment history, and blood/health status make transplant safer or more effective.
BolognaAges 18–73 - NCT05202314Recruiting
Camrelizumab plus chemo after stent for left bowel cancer
This study tests whether adding camrelizumab (an immune therapy) to chemotherapy—after a stent is placed to open a blocked left-sided colon—improves outcomes. It’s meant for people whose cancer can still be removed with surgery after the blockage is treated.
Beijing, Beijing MunicipalityAges 18–80 - NCT05314400Recruiting
MRI with contrast for metastatic colon cancer liver lesions
This trial studies an MRI technique using a contrast dye (gadopetate/gadolinium) to better look at liver lesions that may be colon cancer spread. It may help doctors more accurately assess which liver tumors are present and guide next steps.
London, OntarioAges 18 years+ - NCT05970133Recruiting
Robotic surgery vs laparoscopy for left colon cancer
This trial compares two ways to remove left-sided colon cancer and take the specimen out through the anus (without a large external incision). It may help find which approach is safer and more effective for curing Stage I–III disease.
TaipeiAges 18 years+ - NCT06081647Recruiting
Testing a new airway device for endoscopy
This trial tests a special mouth-and-throat device designed to help you breathe easier during a routine endoscopy or colonoscopy. If you are a generally healthy adult scheduled for one of these procedures, you may be able to join.
Nanjing, JiangsuAges 18–60 - NCT06204484Recruiting
MRD-guided Chemo Timing for Early Colon Cancer
This trial is for people with early-stage colon cancer (stage II high-risk or stage III low-risk) that is not MSI-H. It uses a blood test (MRD) to see if you can safely delay or skip extra chemotherapy after surgery, based on whether the test finds any leftover cancer cells.
Guangzhou, GuangdongAges 18–70 - NCT06287814Recruiting
Blood test to detect leftover cancer DNA in colorectal cancer patients
This study uses a simple blood test (liquid biopsy) to look for tiny bits of tumor DNA remaining after colorectal cancer surgery. It aims to see if the test can help predict whether the cancer will come back, especially in people with stage III cancer who will receive chemotherapy.
Montpellier, HéraultAges 18 years+ - NCT07380867Enrolling by invitation
New marker test for marking colon tumors before surgery
This trial tests a new marker that glows under special light to help doctors see exactly where a colon tumor is during surgery. It may help make the surgery more precise.
Seoul, SeoulAges 19–80 - NCT03280511RecruitingPhase 2
After surgery chemo sprayed into the abdomen for high-risk colon cancer
This Phase 2 study tests whether spraying chemotherapy into the abdomen (through a small procedure) after colon cancer surgery can lower the chance the cancer comes back. It is meant for people with high-risk tumor features but who have had surgery and have no proven relapse yet.
OdenseAges 18 years+ - NCT07433673RecruitingPhase 2
Gemcitabine, cisplatin, nab-paclitaxel, and cemiplimab for locally advanced bile duct cancer
This trial tests a combination of four drugs to see if they shrink locally advanced bile duct or gallbladder cancer that cannot be removed surgically. It is for people who have not had prior treatment for this cancer.
New York, New YorkAges 18 years+ - NCT07462143RecruitingPhase 2/Phase 3
New drug plus chemo for advanced colorectal cancer
This trial tests a new drug (RC148) combined with standard chemotherapy as a first treatment for colorectal cancer that has spread or cannot be removed. The goal is to see if this combination works better than chemotherapy alone.
Beijing, Beijing MunicipalityAges 18–75 - NCT07314996Recruiting
Laparoscopic vs. open surgery for colon cancer with belly fat
This trial compares laparoscopy (minimally invasive) and open surgery for treating colon cancer in people with extra belly fat around internal organs (visceral obesity). The goal is to see which approach gives better recovery and outcomes.
Hangzhou, ZhejiangAges 18–75 - NCT06864338Recruiting
Pilot study for a new colorectal cancer screening test
This study tests a new stool-based test for detecting colorectal cancer and advanced polyps. It aims to see how well it works compared to a colonoscopy. The results may lead to a simpler screening option.
Morrisville, North CarolinaAges 18 years+ - NCT06458998Enrolling by invitation
Improving cancer screening for veterans
This study looks at ways to help veterans get screened for liver cancer (hepatocellular carcinoma) and colorectal cancer. The goal is to see if certain programs or tools can make it easier for veterans to complete these important cancer screenings.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07764497RecruitingPhase 2
Chemotherapy through liver artery for colorectal cancer that spread to liver
This trial tests giving chemotherapy directly into the liver artery for people whose colorectal cancer has spread only to the liver and cannot be surgically removed. The goal is to shrink the tumors and make the liver healthy enough for surgery.
Toronto, OntarioAges 18 years+ - NCT06649123Recruiting
Rectal mucus test for colorectal cancer diagnosis
This trial is testing a new way to check for colorectal cancer by looking at a sample of rectal mucus. It's for people who have been referred for urgent cancer evaluation and may help find cancer earlier.
Telford, ShropshireAges 18–99 - NCT07427537Recruiting
Studying nerve damage from chemotherapy in colorectal and lung cancer patients
This study looks for small molecules in the blood that might predict nerve damage caused by certain chemotherapies. If you have colorectal or lung cancer and are starting a specific chemo plan, this trial could help researchers understand why some people get nerve problems and others don't.
Clermont-FerrandAges 18 years+ - NCT04491929Recruiting
Radiation treatment for colon cancer in the liver using tiny beads
This trial studies a targeted liver radiation procedure that uses tiny radioactive beads to treat colon cancer spread mostly in the liver. It may help people whose liver tumors cannot be removed or treated with other common local treatments, but it has several safety and “screening” checks.
Aarhus N, DanmarkAges 18 years+ - NCT05861505RecruitingPhase 3
Treatment for new liver spread from colon cancer recurrence
This Phase 3 trial studies a treatment approach for people whose colorectal cancer has come back in the liver within 12 months and can be treated with local procedures. It aims to see whether the study treatment can improve outcomes compared with standard care for people with a limited number of liver tumors.
AmsterdamAges 18 years+ - NCT06050200Recruiting
Growth Observation in Liver Surgery
This trial studies a way to help people who need liver surgery but have a very small remaining liver after the operation. It tests a special growth observation approach to see if it can safely increase the size of the future liver remnant.
Warsaw, Masovian VoivodeshipAges 18–80 - NCT06179602Recruiting
Study of thermal ablation for liver tumors
This study follows patients who are having a procedure called thermal ablation to treat liver tumors. It aims to learn more about how well the procedure works and how safe it is.
LeidenAges 18–110 - NCT06185556RecruitingPhase 2/Phase 3
New treatments for liver tumors near blood vessels or bile ducts
This trial tests two procedures—irreversible electroporation and stereotactic body radiotherapy—for people whose colorectal cancer has spread to the liver (1–3 tumors near major blood vessels or bile ducts) and can't be surgically removed or treated with heat. The goal is to see if these approaches can safely destroy those hard-to-reach tumors.
Amsterdam, North HollandAges 18 years+ - NCT06630624RecruitingPhase 1/Phase 2
IP-001 with ablation for colorectal liver metastases
This trial tests whether adding the drug IP-001 to tumor ablation (microwave or irreversible electroporation) helps control colorectal cancer that has spread to the liver. The goal is to find the best dose and see how the immune system responds.
Amsterdam, North HollandAges 18 years+ - NCT06696534Recruiting
Patient views on colorectal cancer screening methods
This study asks people aged 50–69 about their experience and preferences with different screening methods for colorectal cancer. It aims to improve screening programs by understanding what patients prefer.
LisbonAges 50–69
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Common questions
- Are there clinical trials for colon cancer?
- Yes. Clin2 currently lists 292 recruiting colon cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colon cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colon cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.