Clinical trials
Colonization clinical trials
Below are recruiting colonization clinical trials, each written for real people, not researchers. We’re tracking 445 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06242418RecruitingPhase 2
ctDNA-Guided Chemo for Stage III Colon Cancer
This trial tests whether checking for cancer DNA in your blood (ctDNA) can help doctors decide if you need extra chemotherapy after surgery for stage III colon cancer. It aims to personalize treatment and avoid unnecessary chemo.
Guiyang, GuizhouAges 18–75 - NCT06270017RecruitingPhase 1/Phase 2
Zebrafish Avatars for Colon Cancer Treatment
This trial uses tiny zebrafish to grow a piece of your tumor and test which treatments might work best for you. It is for patients with colon cancer who are scheduled for surgery to remove their tumor.
Linköping, Östergötland CountyAges 18 years+ - NCT06271538RecruitingPhase 4
Skal Pro Powder for IBS symptoms
This study tests if Skal Pro Powder, a probiotic, can help relieve symptoms of Irritable Bowel Syndrome (IBS). It is for adults with any type of IBS who haven't used certain other treatments recently.
Kubang Kerian, KelantanAges 18 years+ - NCT06293625RecruitingPhase 3
Chemotherapy before surgery for colon cancer in older adults
This trial tests whether giving 6 weeks of chemotherapy (FOLFOX) before surgery can help people aged 70 and older with locally advanced colon cancer. It aims to make treatment safer and more effective for older adults.
DijonAges 70 years+ - NCT06368141RecruitingPhase 2
Chemo plus immunotherapy before surgery for colon cancer
This trial tests whether giving chemotherapy followed by an immunotherapy drug (a checkpoint inhibitor) before surgery helps shrink locally advanced colon cancer. It is for people with a specific tumor type (MSS and RAS mutation) who have not had prior treatment.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06370884RecruitingPhase 1
Gut bacteria transplant after colon surgery
This study tests whether transplanting healthy gut bacteria into people who have had part of their colon removed can improve recovery. It may help prevent infections or other complications after surgery.
Minneapolis, MinnesotaAges 18–75 - NCT06385418RecruitingPhase 2
Colon chemotherapy for colorectal cancer
This trial tests putting a chemo drug (fluorouracil) directly into the colon through a tube. It's for people with colorectal cancer who are already getting other cancer treatment, to see if adding local chemo helps shrink the main tumor.
Nanjing, JiangsuAges 18–75 - NCT06434896Recruiting
Blood test to guide chemotherapy in stage II colon cancer
This trial is for people with stage II colon cancer who are not currently getting chemotherapy. It uses a blood test to look for tumor DNA, so doctors can decide if chemotherapy might help prevent the cancer from coming back.
's-HertogenboschAges 18 years+ - NCT06485609Recruiting
Dye-guided surgery for right colon cancer
This trial tests whether adding a special dye (indocyanine green) during surgery to remove right-sided colon cancer helps the surgeon see and remove more lymph nodes. The goal is to improve cancer removal without adding extra risks.
GuangzhouAges 18–75 - NCT06490536RecruitingPhase 3
Testing a new treatment for high-risk colon cancer after surgery
This trial tests a new treatment approach for people with certain high-risk colon cancers (stage II or III in the upper colon) after surgery. It aims to see if adding a study drug can help prevent the cancer from coming back.
BerlinAges 18 years+ - NCT06530303RecruitingPhase 1/Phase 2
Personalized immune cell therapy for colorectal cancer
This trial tests a treatment made from your own immune cells (called TILs) that are taken from your tumor, grown in a lab, and given back to you along with immunotherapy. It is for people with advanced colon or rectum cancer who have run out of standard options.
Beijing, Beijing MunicipalityAges 16–90 - NCT06567782RecruitingPhase 2
Immunotherapy plus chemotherapy vs. chemotherapy alone for stage 3 colon cancer
This trial tests whether adding the immunotherapy drug dostarlimab to standard chemotherapy (CAPEOX) is more effective than chemotherapy alone for people with a specific type of colon cancer (MMRp/MSS) that has not spread. It is given before surgery to shrink the tumor.
AalstAges 18 years+ - NCT06580574RecruitingPhase 2
Immunotherapy to save the stomach or colon from surgery
This trial tests whether using immune checkpoint inhibitors alone (like checkpoint blockade drugs) can help people with certain gastric or colon cancers avoid surgery. It's for patients whose tumors have a specific genetic feature called dMMR/MSI-H and haven't spread to other parts of the body.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06686576RecruitingPhase 3
Study of QL1706 before surgery for MSI-H colon cancer
This trial tests a new immunotherapy medicine (QL1706) given before surgery to treat colon cancer that hasn't spread yet. It's designed for patients whose tumors have a specific gene feature (MSI-H/dMMR) and who haven't had any prior treatment for this cancer.
GuangzhouAges 18–75 - NCT06692179RecruitingPhase 1
Testing a freeze-dried fecal transplant during colon surgery
This trial tests if giving a special freeze-dried mixture of healthy gut bacteria right after colon surgery is safe and possible. It may help patients recover better after the procedure.
Minneapolis, MinnesotaAges 18–75 - NCT07255729Recruiting
Blood Test for Colon Cancer Staging
This study looks at a new blood test that may help doctors better understand how far colon cancer has spread. By testing a sample of your blood (taken before surgery), researchers hope to find patterns that predict the stage of cancer and help guide treatment decisions.
Duarte, CaliforniaAges 18 years+ - NCT06709885RecruitingPhase 2
HDAC inhibitor with chemoimmunotherapy before colon cancer surgery
This trial tests adding an HDAC inhibitor to standard chemotherapy and immunotherapy before surgery for a type of colon cancer called pMMR that has grown into nearby fat or deeper. The goal is to see if this combination can shrink the tumor more effectively and improve outcomes.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06731894RecruitingPhase 2
Cannabis for nerve pain after chemotherapy in breast and colon cancer survivors
This trial tests whether a cannabis-based product can reduce nerve damage (neuropathy) caused by chemotherapy in people who have finished treatment for breast or colon cancer. It focuses on survivors who still have pain, numbness, or tingling in their hands or feet.
Duarte, CaliforniaAges 18 years+ - NCT06802991Recruiting
Optimized post-discharge care for older colon cancer patients
This trial tests better nutrition and follow-up care for older patients after colon cancer surgery. It focuses on people who are somewhat frail and at risk for poor nutrition, to see if extra support at home can improve recovery.
HerlevAges 65 years+ - NCT06805994RecruitingPhase 1
Restoring infant nose bacteria after staph treatment
This study tests whether giving a nasal spray of healthy bacteria to infants can restore good germs in the nose after they receive mupirocin ointment to treat Staph aureus. It aims to bring back a healthy nasal microbiome.
Baltimore, MarylandAges birth–60 years - NCT06830239RecruitingPhase 2
Neoadjuvant dostarlimab for resectable stage III colon cancer
This trial tests an investigational immunotherapy drug called dostarlimab given before surgery for colon cancer. It is for people whose tumor is MMR-proficient (also called MSS) and is large enough or has spread to nearby lymph nodes but not to other parts of the body. The goal is to see if this treatment can shrink the tumor before surgery.
LeuvenAges 18 years+ - NCT06923787RecruitingPhase 2
Lidocaine for colon cancer surgery recovery
This trial tests whether giving lidocaine through an IV during and after colon cancer surgery can help with recovery and boost your immune system. It's for people having laparoscopic colon surgery who haven't had chemotherapy before.
LjubljanaAges 18–80 - NCT06940947RecruitingPhase 3
Endoscopy or surgery for early colon cancer
This trial compares a newer, less invasive endoscopic procedure with standard surgery for people who have a small, early-stage colon cancer. The goal is to see if the endoscopic treatment is as effective as surgery while being gentler on the body.
GdanskAges Any age - NCT06958926Recruiting
Study of colon cancer that returns after surgery
This study looks at colon cancer that comes back in the same area after surgery. It may help doctors understand how to better treat this type of recurrence.
HsinchuAges 18 years+
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Common questions
- Are there clinical trials for colonization?
- Yes. Clin2 currently lists 445 recruiting colonization studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colonization trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colonization trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.