Clinical trials
Colonization clinical trials
Below are recruiting colonization clinical trials, each written for real people, not researchers. We’re tracking 436 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05835206RecruitingPhase 2
Drug to reduce antibiotic-resistant gut bacteria
This Phase 2 study tests whether an investigational treatment can help clear or reduce antibiotic-resistant bacteria living in the gut. It may help prevent these germs from causing future infections by targeting specific resistant bacteria found on stool or rectal swabs.
Atlanta, GeorgiaAges 18 years+ - NCT05773144Recruiting
Exercise program during chemotherapy for colon cancer recovery
This trial tests an aerobic exercise plan during chemotherapy for people with stage II or III colon cancer. It compares different exercise approaches to see if exercise can be done safely and may improve how you tolerate treatment and recovery.
Oakland, CaliforniaAges 18 years+ - NCT05534087RecruitingPhase 3
Blood test guided chemo after colon cancer surgery
This study tests whether giving additional (adjuvant) chemotherapy based on a special blood test—circulating tumor DNA (ctDNA)—can lower the risk of colon cancer coming back. It targets people with stage II–III colon cancer whose blood test is positive for minimal residual disease (MRD) after completing standard chemo.
BusanAges 19–75 - NCT05394714RecruitingPhase 1
Magicell-NK cell therapy after colon cancer surgery
This early-stage trial tests an individualized immune cell treatment (Magicell-NK) made from your own cells to help prevent colon cancer from coming back after surgery. It studies safety and how well the treatment works in people with early-stage colon cancer.
TaoyuanAges 20 years+ - NCT05393609Recruiting
Quality-of-life study during surgery for diverticular disease
This trial studies how people’s quality of life changes around diverticular disease surgery. It may help doctors understand what to expect and how to better support patients before and after surgery.
Randers, Central JutlandAges 18 years+ - NCT05345613RecruitingPhase 4
Tranexamic acid during colon scope removal procedures
This trial tests whether tranexamic acid (a medicine that helps reduce bleeding) lowers bleeding during colon procedures where abnormal growths are removed with a flexible camera. You might benefit if you’re having one of these colonoscopic resection procedures and don’t have certain key risk factors.
Be’er Ya‘aqovAges 18 years+ - NCT05239546RecruitingPhase 2
Dostarlimab before colon surgery for mismatch-repair–deficient cancer
This study tests dostarlimab given before surgery for stage II or III colon cancer that has a specific DNA repair defect. It aims to shrink or control the cancer so that some people may be able to skip surgery if the results are good.
Iowa City, IowaAges 18 years+ - NCT05179889RecruitingPhase 2/Phase 3
Chemo after surgery for high-risk stage III colon cancer
This trial tests giving mFOLFIRINOX chemotherapy after curative surgery for people with high-risk stage III colon cancer. It aims to lower the chance that cancer comes back.
DaejeonAges 20–75 - NCT05174169RecruitingPhase 2/Phase 3
Adjuvant colon chemotherapy guided by tumor DNA results
This trial tests whether treatment for colon cancer after surgery can be guided by a blood test that looks for leftover cancer signals (ctDNA). It may help some people choose stronger or different chemo based on whether ctDNA is found after surgery.
Birmingham, AlabamaAges 18 years+ - NCT04920032RecruitingPhase 1
Blood test–guided extra treatment for colon cancer recurrence risk
This Phase 1 study uses a blood test called ctDNA to decide whether and how to adjust treatment in people with colon cancer who still have a small amount of disease left after surgery. If your blood test remains positive, the trial aims to reduce recurrence risk by guiding treatment changes.
Orange, CaliforniaAges 18 years+ - NCT04185272Recruiting
Study of a cancer-related protein in colon cancer
This study looks at how a protein called butyrophilin is involved in colon cancer. It may help researchers understand colon cancer better and guide future treatments.
MarseilleAges 18 years+ - NCT04120701RecruitingPhase 3
Using blood DNA tests to guide colon cancer treatment after surgery
This trial tests whether a blood test that looks at cancer DNA can help decide whether you need “adjuvant” (extra) chemotherapy after colon cancer surgery. It may help some patients avoid unnecessary chemotherapy while still keeping the cancer from coming back.
DijonAges 18–75 - NCT03026140RecruitingPhase 2
Tested immune therapy before surgery for early colon cancer
This Phase 2 trial tests immune “checkpoint” medicines (and combinations) given before colon surgery to see if they can better control early colon cancer. It is aimed at people with non-metastatic colon cancer and certain tumor markers.
AmsterdamAges 18 years+ - NCT07878988RecruitingPhase 1
Study of LTZ-232 for advanced colorectal and other solid tumors
This study tests an experimental drug called LTZ-232 in people with advanced colorectal cancer or other solid tumors that have not responded to standard treatments. The goal is to see if it is safe and if it can shrink or slow the growth of tumors.
Scottsdale, ArizonaAges 18 years+ - NCT07805369RecruitingPhase 1
Study of DEM301 for advanced colorectal cancer
This trial tests a new drug called DEM301 for people with advanced colorectal cancer that has stopped responding to standard treatments. The goal is to see if DEM301 can help shrink or control the cancer.
Nedlands, Western AustraliaAges 18 years+ - NCT06239194RecruitingPhase 1/Phase 2
MdX2001 for advanced solid tumors
This trial tests a new drug, MDX2001, for people with advanced solid tumors that have spread. The study aims to find the best dose and see how well it works.
Denver, ColoradoAges 18 years+ - NCT03925662RecruitingPhase 3
Mebendazole added to stage 4 colon cancer care
This trial studies whether adding mebendazole (an existing anti-parasite medicine) to standard treatment can improve outcomes for people with stage 4 colon cancer. You might qualify if you have stage 4 colorectal cancer and none of the key safety concerns.
CairoAges 18 years+ - NCT03643718Recruiting
Emergency surgery and trauma patient registry online
This trial is a web-based registry that collects information about people who need emergency surgical or non-surgical treatment for sudden (acute) problems. Your information can help doctors better understand and improve emergency care and decision-making.
PisaAges Any age - NCT05185245Recruiting
Liver transplant for colorectal cancer spread to the liver
This study looks at whether a liver transplant can help people whose colorectal cancer has spread to the liver but cannot be removed by surgery. It also checks whether certain cancer features, treatment history, and blood/health status make transplant safer or more effective.
BolognaAges 18–73 - NCT04478851Recruiting
Exercise program to help people live well with cancer
This study offers an exercise program meant to help people with cancer improve how they live day to day. It may fit you if you are getting treatment now, starting soon, or finished within the last 5 years and can safely do mild activity.
Calgary, AlbertaAges 18–100 - NCT05426135Recruiting
AI tool to assess cancer risk and guide care
This study tests an artificial intelligence (AI) system that uses your health information and medical images to better judge cancer risk and support diagnosis and treatment decisions. It may help doctors make more consistent assessments by combining clinical records, imaging, and other lab-style data.
Wuhan, HubeiAges 18–75 - NCT05434026Recruiting
Colorectal cancer database study for people having surgery
This study enrolls people with colon cancer found on biopsy and who are able to have surgery. It mainly builds a medical database to help researchers understand care and outcomes, and it depends on you consenting to participate.
BeijingAges Any age - NCT03280511RecruitingPhase 2
After surgery chemo sprayed into the abdomen for high-risk colon cancer
This Phase 2 study tests whether spraying chemotherapy into the abdomen (through a small procedure) after colon cancer surgery can lower the chance the cancer comes back. It is meant for people with high-risk tumor features but who have had surgery and have no proven relapse yet.
OdenseAges 18 years+ - NCT04527861Recruiting
Minimally invasive single-incision surgery for colon cancer
This trial compares a single-incision laparoscopic operation versus the usual laparoscopic operation for colorectal (colon or “high rectum”) cancer. It looks at cancer outcomes and may help determine which approach is safer and works better for the right patients.
Lanzhou, GansuAges 18–85
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Common questions
- Are there clinical trials for colonization?
- Yes. Clin2 currently lists 436 recruiting colonization studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colonization trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colonization trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.