Clinical trials
Colorectal Cancer (Diagnosis) clinical trials
Below are recruiting colorectal cancer (diagnosis) clinical trials, each written for real people, not researchers. We’re tracking 349 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05775146RecruitingPhase 2
Radiation to liver metastases after colon cancer treatment
This trial studies giving targeted high-dose radiation (SBRT) to liver metastases from colorectal cancer after initial treatment, with the goal of improving long-term control or cure. It may help people who have a limited number of liver spots that doctors think can be treated safely and effectively.
Edmonton, AlbertaAges 18 years+ - NCT06307249RecruitingPhase 1
Precision therapy for solid tumors targeting CDK4/6 and VEGF
This trial tests a combination of two targeted drugs for advanced solid tumors like colorectal, lung, breast, and genitourinary cancers. The goal is to see if blocking certain proteins and a long RNA molecule can slow tumor growth.
Tripoli, North LebanonAges 18 years+ - NCT06500052RecruitingPhase 1
Study of BL-M17D1 for HER2-positive or low-expression digestive tract and other solid tumors
This trial tests a new drug called BL-M17D1 for people with advanced or metastatic HER2-positive or low-expression gastrointestinal cancer and other solid tumors. The goal is to see if it is safe and effective.
Guangzhou, GuangdongAges 18–75 - NCT07227636RecruitingPhase 2
Immunotherapy for ctDNA-positive colorectal cancer after surgery
This trial tests two immunotherapy drugs, botensilimab and balstilimab, for people with colorectal cancer who have had surgery and chemotherapy but still have detectable cancer DNA in their blood. The goal is to see if these drugs can help clear the remaining cancer cells.
Basking Ridge, New JerseyAges 18 years+ - NCT07696793RecruitingPhase 4
Simethicone colonoscopy prep for cancer screening
This trial tests a colonoscopy preparation drink that contains simethicone (a gas-relief ingredient) to see if it works better than standard prep for people who are already scheduled for a screening colonoscopy after a positive stool test. It may help make the procedure more comfortable and effective.
Barcelona, BarcelonaAges 50–69 - NCT05673148RecruitingPhase 3
Ablation treatment plus usual therapy for limited metastatic bowel cancer
This study tests whether adding “total ablation” (carefully destroying all visible small tumors using surgery, heat/cold treatment, and/or targeted radiation) to standard chemotherapy improves outcomes for people with limited spread of colorectal cancer. It may help by aiming to eliminate all known metastatic spots while you continue usual cancer treatment.
Kingman, ArizonaAges 18 years+ - NCT03494946Recruiting
Liver transplant vs chemotherapy for colon cancer liver spread
This trial compares liver transplantation to standard chemotherapy for people with colon or rectal cancer that has spread to the liver but cannot be removed surgically. It looks at whether transplant can help patients live longer or better than chemotherapy in the right patients.
OsloAges 18 years+ - NCT04967183Recruiting
Compare a stool blood test versus colonoscopy follow-up after precancer removal
This study compares two ways of checking for colorectal cancer risk after advanced polyps are removed. It may help determine whether a stool test can safely replace some colonoscopy surveillance for certain people.
OurenseAges 50–65 - NCT05336539Recruiting
Community screening study for colorectal cancer using methylation testing
This study recruits adults in Yangzhou to help screen for colorectal cancer risk using a lab test based on “methylation,” a way cells can carry disease-related changes. You would mainly complete a risk questionnaire and phone follow-ups, and agree to share any cancer diagnosis information during the study.
Yangzhou, JiangsuAges 40–74 - NCT06413212Recruiting
Personalized drug test for advanced cancer with fluid buildup
This trial uses a special test on your cancer cells to find which chemotherapy might work best for you. The aim is to treat advanced cancer that has caused fluid buildup in the chest or abdomen.
Wuhan, HubeiAges 18 years+ - NCT06449937Recruiting
Local liver treatment for colorectal cancer that has spread
This trial tests whether treating liver tumors with surgery or ablation can help people whose colorectal cancer has spread to the liver and other organs. It may be an option if you've had only 1 or 2 types of chemotherapy and your non-liver metastases are stable.
Chuzhou, AnhuiAges 18–80 - NCT06689293Recruiting
Stool test for follow-up after colorectal cancer treatment
This trial is testing whether a simple stool test (FIT) can replace some follow-up colonoscopies or CT scans for people who have been treated for colorectal cancer. If you are due for a routine check-up after your cancer surgery, you may be able to take this test at home instead of having a more invasive procedure.
NottinghamAges 18 years+ - NCT06749015Recruiting
Study for BRAFV600E Mutant Metastatic Colorectal Cancer
This trial tests a treatment for people whose colorectal cancer has spread and cannot be removed by surgery, and who have a specific gene change called BRAFV600E. It aims to find out if the treatment can help shrink or control the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06846268RecruitingPhase 2
New drug combo before surgery for colorectal cancer
This trial tests two immunotherapy drugs (ADG126 and pembrolizumab) given before surgery for locally advanced colorectal cancer that hasn't spread. It aims to shrink tumors and improve outcomes.
SingaporeAges 21 years+ - NCT07296887Recruiting
Care tool study for cancer teams and patients
This study tests a new care tool for people with gynecologic, prostate, lung, or colorectal cancer. It helps your care team (doctors, nurses, social workers) and patients like you see if the tool improves support and communication.
Alton, IllinoisAges 18 years+ - NCT05755672Recruiting
Study biomarkers during curative-intent treatment for metastatic colon cancer
This study looks at biological markers (substances measured in the body) during treatment for metastatic colorectal cancer. It may help doctors better understand how treatment works, using patients who are treated with a goal of cure.
Lund, Skåne CountyAges 18–110 - NCT07042243Recruiting
Florida ASCENT cancer study for patients and providers
This study looks at cancer care in Florida. If you have had cancer in the past and are not currently getting active treatment (like chemotherapy or radiation), this study may help researchers understand how to improve care.
Gainesville, FloridaAges 18–100 - NCT05101382Recruiting
Study of colorectal cancer records to improve future research
This retrospective study uses existing colorectal cancer imaging and/or preserved tissue samples to support more precise (personalized) research. It may help researchers better understand colorectal cancer over time, but it does not involve new treatment.
Genova, GEAges 18 years+ - NCT06136949Recruiting
STARD3 study for colorectal cancer patients
This study looks at a marker called STARD3 in colorectal cancer to understand its role and potential for targeted treatment. It may help find new ways to treat the disease.
Aviano, PordenoneAges 18 years+ - NCT06545630RecruitingPhase 1
Personalized immune cell vaccine for colorectal cancer with liver spread
This trial tests a personalized vaccine made from your own immune cells (dendritic cells) that are trained to recognize colorectal cancer. It is for people who had surgery for colorectal cancer that spread to the liver and are now at high risk for the cancer returning.
Chengdu, Chengdu/SichuanAges 18–75 - NCT06911970Recruiting
Exercise and immune response in cancer treatment
This trial tests whether aerobic exercise can help your immune system fight cancer better during chemotherapy or immunotherapy. It is for people with breast or colon cancer that has not spread to other parts of the body.
Sherbrooke, QuebecAges 40–70 - NCT07024225Recruiting
A look back at colon and rectal cancers
This study reviews medical records of people with colon or rectal cancer to better understand the disease. It helps researchers learn more without any new treatments or procedures.
Sohag, Sohag GovernmentAges 18–80 - NCT06607458RecruitingPhase 2
Liver-focused chemo for metastatic colorectal cancer
This trial tests giving high-dose melphalan directly into the liver's blood supply, followed by standard cancer therapy, for people whose colorectal cancer has spread mainly to the liver. The goal is to see if this approach is safer and works better than standard treatment alone.
Duarte, CaliforniaAges 18 years+ - NCT06601075Recruiting
FDG and FAPI PET Scans for Advanced Colorectal Cancer
This trial uses two types of PET/CT scans (FDG and FAPI) to better see and track colorectal cancer that has spread to the belly lining (peritoneum). It aims to help doctors choose the best treatment by improving how they detect and monitor the cancer.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for colorectal cancer (diagnosis)?
- Yes. Clin2 currently lists 349 recruiting colorectal cancer (diagnosis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal cancer (diagnosis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal cancer (diagnosis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.