Clinical trials
Colorectal cancer clinical trials
Cancer of the colon or rectum, often beginning as small growths called polyps. We’re tracking 1,068 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07391956Recruiting
Palliative care for advanced heart failure or cancer
This study tests whether special supportive care (called tiered palliative care) can help people with advanced heart failure or certain advanced cancers feel better and have fewer hospital visits. If you live in Manhattan or Queens, speak English or Spanish, and meet the other requirements, you may be able to join.
Astoria, New YorkAges 18 years+ - NCT07602504Recruiting
Metastatic Liver Cancer Patient Registry Study
This study collects health information from patients with cancer that has spread to the liver. Researchers will track your medical history and outcomes to better understand how metastatic liver cancer develops and progresses.
Bengbu, AnhuiAges 18–80 - NCT07167446RecruitingEarly Phase 1
CBD to prevent nerve damage from oxaliplatin in colorectal cancer
This trial tests if cannabidiol (CBD) can prevent nerve damage (neuropathy) caused by the chemotherapy drug oxaliplatin. If you have colorectal cancer that has spread or cannot be removed by surgery and you are about to start oxaliplatin, you may be able to join.
Philadelphia, PennsylvaniaAges 18 years+ - NCT04815525Recruiting
Long-term bowel cancer risk after colonoscopy in Hong Kong
This study follows people in Hong Kong over time to learn how the future risk of advanced colon growth changes after they have a colonoscopy. It may help doctors better predict who needs closer follow-up in the years after a colonoscopy.
Shatin, New TerritoriesAges Any age - NCT05879783Recruiting
Optical biopsy during surgery for colorectal belly tumors
This trial looks at using a special light-based method (optical biopsy) to examine small growths on the lining of the abdomen during colorectal cancer surgery. It may help doctors better assess these peritoneal nodules while you are already having an operation.
Guangzhou, GuangdongAges 18–85 - NCT06405776Recruiting
Lidocaine for pain and survival after bowel surgery in older adults
This study tests whether a drug called lidocaine, given during surgery, can help control pain after colon or rectal surgery and possibly improve long-term survival in older adults. The goal is to see if lidocaine offers better pain relief and recovery compared to standard care.
SichuanAges 60 years+ - NCT07720245Recruiting
Self-health app study for adults in Hong Kong
This trial tests a mobile app that helps you check your own health. It is for adults in Hong Kong who want to use the app to learn about their health and get tips.
Hong KongAges 25–65 - NCT02754115Recruiting
Audit of surgery with heated chemo for belly tumors
This study is an audit (a review of care) of patients who undergo cytoreductive surgery plus heated chemotherapy placed in the abdomen. It helps doctors understand how this treatment is done and what outcomes and safety it has.
Mumbai, MaharashtraAges 18–70 - NCT07609680Recruiting
Blood Pressure vs. Heart Output Monitoring During Colon Surgery
This trial compares two ways doctors monitor your body's circulation during colorectal surgery. One method tracks blood pressure; the other tracks how much blood your heart pumps. Researchers want to see which approach leads to better outcomes and fewer complications.
Ankara, Yenimahalle\AnkaraAges 18–80 - NCT07397338RecruitingPhase 1/Phase 2
RAS inhibitors with ivonescimab for solid tumors
This trial tests new drugs called RAS(ON) inhibitors combined with ivonescimab for people with solid tumors that have a RAS mutation. It aims to see if this combination can shrink tumors or slow their growth.
Los Angeles, CaliforniaAges 18 years+ - NCT07378930Recruiting
ULTRA-SAFE: More frequent monitoring after advanced polyps
This trial compares a new, more frequent surveillance schedule (yearly stool tests and colonoscopies every 2 years) to the standard schedule for people who have had advanced polyps removed. It aims to see if the extra testing helps prevent future colon cancer.
Taipei, TaipeiAges 40–75 - NCT07284992RecruitingPhase 2
Comparing short vs long radiation with immunotherapy for rectal cancer
This trial tests whether a short course of radiation followed by an immunotherapy drug (PD-L1 inhibitor) plus chemotherapy works as well as or better than a longer radiation course for locally advanced rectal cancer. The goal is to shrink tumors before surgery.
Jinan, ShandongAges 18–80 - NCT07276529Recruiting
Magnet procedure safety trial for colon surgery patients
This trial tests a new magnet device to connect sections of the colon after surgery. It may be an option for people who need part of their colon removed and are otherwise in good health.
Orlando, FloridaAges 22 years+ - NCT07259590RecruitingPhase 1/Phase 2
GFH375 with cetuximab or chemo for KRAS G12D cancers
This trial tests a new drug called GFH375 combined with either cetuximab or chemotherapy for people with advanced solid tumors that have a specific genetic change called KRAS G12D. It's for those whose cancer has worsened after other treatments or who can't have standard therapy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07255066Recruiting
Omega-3 nutrition supplement for advanced lung or colorectal cancer
This trial tests whether a special nutrition supplement (rich in EPA, an omega-3 fat) can help people with advanced lung or colorectal cancer who are losing weight. It aims to improve treatment outcomes and quality of life.
OsloAges 18 years+ - NCT06807073Recruiting
Closing the wound after large colon polyp removal
This study compares closing the wound after removing a large colon polyp to leaving it open. The goal is to see if closing the area reduces bleeding or other problems.
Montreal, QuebecAges 18 years+ - NCT06783491RecruitingPhase 3
Chemotherapy with or without heated chemo for advanced colon cancer
This trial tests if adding heated chemotherapy directly into the abdomen during surgery improves outcomes for people with advanced colon cancer that hasn't spread to other organs. It compares standard chemotherapy before surgery alone versus chemotherapy before surgery plus heated chemo during surgery.
Córdoba, CórdobaAges 18–75 - NCT06680739RecruitingPhase 2
Study of immunotherapy for colorectal and endometrial cancer
This trial tests two immunotherapy drugs, durvalumab and tremelimumab, in people with colorectal or endometrial cancer that has spread or come back. The goal is to understand why some tumors persist or don't respond to treatment.
BarcelonaAges 18 years+ - NCT06663319RecruitingPhase 1
Study of JNJ-89402638 for metastatic colorectal and gastric cancers
This trial tests a new drug, JNJ-89402638, alone or with other treatments for people with metastatic colorectal or gastric cancer that has progressed after standard therapies. It aims to find safe and effective doses and combinations.
Tucson, ArizonaAges 18 years+ - NCT06528990RecruitingPhase 2
Telehealth help for ostomy self-care
This study tests a telehealth program to help you manage your ostomy after surgery. If you have bladder or colorectal cancer and are getting an ostomy, you and a caregiver can learn skills to handle your new stoma from home using video calls.
Duarte, CaliforniaAges 18 years+ - NCT06475560Recruiting
Camera capsule endoscopy for colorectal disease diagnosis
This trial tests a camera pill (capsule endoscopy) as an alternative to a regular colonoscopy for people with colon or rectum symptoms. It's a simpler way to look inside your large intestine without a tube.
Odense CAges 18 years+ - NCT06335420Recruiting
Can carrot juice prevent colon polyps from coming back?
This study tests whether drinking carrot juice every day can lower the chance that large colon polyps or early colon cancers will come back. Researchers want to see if the nutrients in carrot juice help protect the lining of the colon.
OdenseAges 18 years+ - NCT06271941Recruiting
Reducing polyp return after large colon polyp removal
This trial is testing a standard way to remove large polyps from the colon and checking if it helps prevent them from coming back. It's for people who have a large non-cancerous polyp that needs to be taken out during a colonoscopy.
Montreal, QuebecAges 18 years+ - NCT06193356Recruiting
Can endoscopists learn to spot scar after polyp removal?
This study tests whether endoscopists can learn to see scarring and find any remaining tissue after polyp removal. It may help improve how doctors check for cancer coming back.
GhentAges 18 years+
Hear when a new Colorectal cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for colorectal cancer?
- Yes. Clin2 currently lists 1,068 recruiting colorectal cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.