Clinical trials
Complication clinical trials
Below are recruiting complication clinical trials, each written for real people, not researchers. We’re tracking 1,144 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05487612Recruiting
MiECC heart-lung machine vs standard bypass during heart surgery
This trial compares a newer heart-lung machine setup (MiECC) with the usual bypass technique during certain heart operations. It may help see whether MiECC changes outcomes like the need for blood transfusions or recovery after surgery.
TorontoAges 18–85 - NCT05491434Recruiting
Study of muscle loss in colon cancer patients
This trial looks at muscle loss (called sarcopenia) in people with colon cancer to test an intervention that may help strength or recovery. If you’re age 70 or older and meet the cancer and health requirements, you may be able to take part.
L'Hospitalet de Llobregat, BarcelonaAges 70 years+ - NCT05492708Recruiting
Pregnancy study for first-time-to-mid pregnancy participants in Heartland states
This study is enrolling pregnant people who are early in pregnancy and live in certain Heartland states. It aims to learn from participants during pregnancy and may help researchers better understand pregnancy care needs.
Indianapolis, IndianaAges 18 years+ - NCT05503849Recruiting
Pregnancy study for women early in pregnancy in Guangzhou
This study enrolls pregnant women who are early in pregnancy and plan to deliver and live in Guangzhou. It will test a “born in Guangzhou” type intervention to see if it improves pregnancy outcomes or newborn health.
GuangzhouAges 18–50 - NCT05518643Recruiting
Testing a stress-reducing recovery plan for pancreatic surgery patients
This trial tests how well a structured hospital recovery plan (called ERAS) works for people having pancreatic surgery. It looks at stress and recovery outcomes to see if patients may do better with this approach.
LarissaAges 18 years+ - NCT05522218Recruiting
Eluvia stent for blocked or narrowed leg artery
This trial looks at using an Eluvia drug-coated stent to treat a blocked or severely narrowed artery in the upper leg/knee area. It may help improve blood flow to the leg, and the study will follow patients to see how they do over time.
Hangzhou, ZhejiangAges Any age - NCT05527717RecruitingPhase 4
PCI vs strategy for heart attack shock needing ECMO
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
SeoulAges 19 years+ - NCT05530655RecruitingEarly Phase 1
Finding the best lisinopril dose to prevent urine side effects
This early study tests which dose of lisinopril works best to help prevent urinary toxicity (urine/burning/urinary side effects) after radiation treatment for prostate cancer. If it’s effective for you, it could make radiation easier to tolerate.
Rochester, New YorkAges 18–70 - NCT05534243Recruiting
A breathing and brain-signal study for adults on ventilators
This study looks at brain activity during care for adults who are on a breathing machine through a tube in the windpipe. It may help doctors understand how to monitor recovery and guide care after intubation.
Iowa City, IowaAges 18 years+ - NCT05536531Recruiting
NMES therapy to help prevent ICU muscle weakness
This trial tests whether a device that delivers small electrical pulses to muscles can help prevent breathing and muscle weakness in very sick ICU patients. It also looks at changes in blood markers that may relate to muscle weakness and recovery.
Santiago, Santiago MetropolitanAges 18 years+ - NCT05539196Recruiting
Registry for Exablate treatment in Parkinson’s with medication problems
This trial is a real-world registry that follows people with Parkinson’s who are planning to get an Exablate 4000 procedure (a focused ultrasound treatment) for one-sided symptoms that are difficult to control with medication. It mainly checks outcomes and safety over time, helping doctors understand how well this treatment works in everyday care.
Baltimore, MarylandAges 30–99 - NCT05544266Recruiting
Study rare diabetes patterns to better guide diagnosis
This study looks at people who may have a “non-typical” form of diabetes, including rare genetic causes or unusual symptoms. It may help your care team understand what type of diabetes you have and whether specific genetic testing could explain it.
Aurora, ColoradoAges Any age - NCT05551104RecruitingPhase 3
Best blood pressure medicine after pregnancy
This study compares two common blood pressure medicines (nifedipine and labetalol) to see which is safest and works best for high blood pressure after childbirth. If you have postpartum hypertension, the trial may offer close monitoring and help doctors choose the safest option for you.
Loma Linda, CaliforniaAges 18 years+ - NCT05561634RecruitingPhase 2
Test targeted medicine with radiation for advanced skin cancer
This Phase 2 study looks at using a medication that blocks the “Sonic Hedgehog” pathway together with radiotherapy to reduce future problems from locally advanced basal cell carcinoma (BCC). It’s for people whose cancer responded completely to the first Sonic Hedgehog pathway inhibitor treatment and where doctors can confirm that response with a tissue test.
LilleAges 18 years+ - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT05577988RecruitingPhase 3
Genetic-guided weaker blood thinner vs stronger standard therapy
This study tests whether switching early to a weaker anti-platelet medicine based on your genetics can reduce bleeding problems in people at high risk for bleeding after a heart attack. It compares this approach to the usual strategy of staying on a stronger anti-platelet medicine.
Paris, IDFAges 18 years+ - NCT05586867Recruiting
Blood testing study in people on hemodialysis
This study looks at blood markers related to iron and other body processes (like minerals, liver function, and inflammation) in people receiving hemodialysis. The results may help doctors better understand what affects health in dialysis patients.
Quincy-sous-SénartAges 18 years+ - NCT05590949Recruiting
Study of bone problems after stopping breast cancer medicines
This observational study looks at bone complications in post-menopausal women with breast cancer after stopping denosumab and an aromatase inhibitor. It may help doctors better understand who is at risk for bone weakening and fractures after these medicines are stopped.
Basking Ridge, New JerseyAges 18 years+ - NCT05599438Recruiting
Fitness and drug use study in recreational athletes
This study follows recreational athletes to understand how past and current anabolic-androgenic steroid (AAS) use relates to fitness changes over time. If you have used these substances in the past (and stopped more than 3 months ago), or you have never used them, you may be able to join.
CopenhagenAges 18 years+ - NCT05599178Recruiting
Doppler ultrasound in the brain vessels before delivery
This study uses a special ultrasound (Doppler) to look at blood flow in a baby’s brain vessels within 24 hours before birth. Researchers want to see whether these findings relate to birth outcomes, like how the baby does right after delivery.
LeuvenAges 18 years+ - NCT05610865RecruitingPhase 1
Stem cell treatment for chronic diabetic foot ulcers
This Phase 1 study tests whether stem cells taken from fat tissue (after a small procedure) can help heal a long-lasting diabetic foot ulcer. It mainly aims to help ulcers that are limited to soft tissue and have good blood flow to the foot.
Lahore, Punjab ProvinceAges 20–60 - NCT05637619Recruiting
3D scan study of natural teeth and dental prosthesis wear
This study uses 3D scans to measure how teeth and dental replacements wear against each other over time. It may help improve how dentists design and fit dentures and full-mouth restorations.
LisbonAges 18 years+ - NCT05654025Recruiting
Study of eyesight outcomes after congenital lens dislocation
This follow-up study looks at how vision changes over time in children and adults with congenital lens dislocation, and what complications may occur. It may help doctors better predict outcomes and prevent problems after diagnosis.
Guangzhou, GuangdongAges 3 years+ - NCT05662696Recruiting
Telemonitoring for pregnant people at high risk of preeclampsia
This study tests whether a home telemonitoring program (sending health readings from home) is practical and helpful for people at high risk for preeclampsia. It may help catch warning signs earlier and support safer care during the first half of pregnancy.
Karachi, SindhAges 18 years+
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Common questions
- Are there clinical trials for complication?
- Yes. Clin2 currently lists 1,144 recruiting complication studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a complication trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a complication trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.