Clinical trials · Pennsylvania
COPD clinical trials in Pennsylvania
We’re tracking 30 recruiting copd studies with a site in Pennsylvania — including Phase 2 and Phase 3 studies, each written for real people, not researchers.
Recruiting studies in Pennsylvania
- NCT06544928Enrolling by invitation
Home monitoring for COPD flare-ups after hospital discharge
This study tests a wearable device that listens to your breathing at home. It may help detect early signs of a COPD flare-up so you can get care sooner. You can join if you have moderate to severe COPD and recently left the hospital for a flare-up.
Philadelphia, PennsylvaniaAges 40–80 - NCT06974981Recruiting
Using lung cancer screening to find and treat COPD
This study looks at how lung cancer screening can also help find and manage COPD, a lung condition that often goes undetected. If you are a current or former smoker and meet certain age and smoking history criteria, you may join to help improve screening and care for both lung cancer and COPD.
Philadelphia, PennsylvaniaAges 50–80 - NCT07684820RecruitingPhase 2
A study of ExPD-101 for COPD with chronic bronchitis and frequent flare-ups
This study tests an experimental drug (ExPD-101) given daily as a pill for 52 weeks for people with COPD who have chronic bronchitis and frequent flare-ups. It compares the drug to a placebo (inactive pill) to see if it reduces flare-ups and improves symptoms.
DuBois, PennsylvaniaAges 40–85 - NCT07646587RecruitingPhase 2
Safety Study of WIN378 for Moderate-Severe COPD
This study tests a new drug called WIN378 in people with moderate-to-severe COPD (chronic lung disease). It will check if the drug is safe and how the body processes it, which may help improve breathing and reduce flare-ups.
DuBois, PennsylvaniaAges 40–80 - NCT05204888Recruiting
Home breathing device study for COPD patients after recent flare-up
This study tests whether a home high-flow nasal breathing device (myAirvo 3) helps people with COPD who recently needed hospital care for a flare-up. You would use the device at home and track symptoms, oxygen levels, and heart rate daily to see how well it works.
Bethlehem, PennsylvaniaAges 30 years+ - NCT07222410Recruiting
Smart oxygen control for COPD patients on nasal high flow
This trial tests a smart oxygen system that automatically adjusts oxygen levels for people with COPD who are in the hospital using a nasal high-flow device. It may help keep your oxygen levels stable without needing constant adjustments.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06933758Recruiting
Temple Health Chest Lung Screening Study
This study looks at how a hospital program can help people who are at risk for lung cancer get the proper screening and follow-up care. You may be eligible if you are a Temple patient and have had a low-dose CT scan for lung cancer screening.
Philadelphia, PennsylvaniaAges 50–80 - NCT07118306Recruiting
COPD flare-up follow-up study
This study is for people with COPD who go to the emergency room for a moderate or severe flare-up. It looks at how they are doing after their visit and whether their current inhaler treatment is working well.
Philadelphia, PennsylvaniaAges 40 years+ - NCT07059091RecruitingPhase 2
Allergy medicine for COPD with indoor allergies
This study tests if omalizumab, an allergy medicine, can help people with COPD who are allergic to common indoor allergens and have had recent flare-ups. It aims to see if reducing allergic reactions can improve COPD control.
Philadelphia, PennsylvaniaAges 40 years+ - NCT07051707Recruiting
Study of a new lung treatment for people with COPD
This trial tests a device called dNerva that targets nerves in the lungs to help people with COPD breathe easier. It is designed for those who have moderate to severe COPD and are not currently smoking.
DuBois, PennsylvaniaAges 40–80 - NCT06883305RecruitingPhase 3
Testing tezepelumab for moderate to severe COPD
This trial tests tezepelumab, an injected medication, for people with moderate to very severe COPD who still have flare-ups despite using standard inhalers. It may help reduce flare-ups and improve breathing for those with higher eosinophil levels.
DuBois, PennsylvaniaAges 40–80 - NCT06878261RecruitingPhase 3
Tezepelumab for moderate to very severe COPD
This study tests a new medication called tezepelumab (given as a shot) to see if it can reduce COPD flare-ups in people with moderate to very severe COPD who have had recent flare-ups despite using inhalers. It may be an option for those with higher levels of eosinophils (a type of white blood cell) in their blood.
Horsham, PennsylvaniaAges 40–80 - NCT06600126Recruiting
Emotional support for people with emphysema and their caregivers
This study tests a program that helps people with COPD (emphysema) who feel sad or down. You and a loved one will get weekly phone or video calls to learn ways to manage emotions and improve your quality of life.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06376994RecruitingPhase 3
Clean air study for COPD
This study tests if using air cleaners at home improves lung health in people with COPD. If you qualify, you may get an air cleaner for your home and be followed for 12 months.
West Reading, PennsylvaniaAges 40 years+ - NCT05033990Recruiting
Study of early COPD changes using breathing tests and scans
This study follows people with early COPD patterns (or no lung disease) to understand how COPD starts and progresses over time. You may have breathing tests and possibly CT scans, and some participants may join an added lung procedure (bronchoscopy).
Philadelphia, PennsylvaniaAges 30–55 - NCT07610395RecruitingPhase 2
Testing an oral drug for cold virus in COPD patients
This trial tests an oral medication (VPV) to see if it can safely treat rhinovirus (a common cold virus) in people with COPD. The goal is to help you recover faster and prevent serious COPD flare-ups.
DuBois, PennsylvaniaAges 40–85 - NCT07759245RecruitingPhase 2
Brenipatide for moderate-to-severe COPD
This trial tests a new medicine called Brenipatide to see if it can help people with moderate-to-severe COPD who still have symptoms despite using standard inhalers. The study will compare the effects of Brenipatide against a placebo to understand if it is safe and effective.
DuBois, PennsylvaniaAges 40–75 - NCT07725939RecruitingPhase 2
Study of Galvokimig for moderate-to-severe COPD with chronic bronchitis
This study tests an experimental drug called Galvokimig (taken as a pill) to see if it can reduce COPD flare-ups and improve lung function in people with moderate to severe COPD and chronic bronchitis. It is for those who have had recent flare-ups and are already using maintenance inhalers.
DuBois, PennsylvaniaAges 40–80 - NCT07714252Enrolling by invitation
Virtual palliative care team for veterans with heart or lung disease
This study tests a virtual team of nurses and social workers who provide palliative care to veterans with heart failure, COPD, or interstitial lung disease. The goal is to improve quality of life by offering extra support at home.
Lebanon, PennsylvaniaAges 18 years+ - NCT07190209RecruitingPhase 3
Testing lunsekimig for COPD with frequent flare-ups
This trial tests a new medicine called lunsekimig for people with COPD that still causes flare-ups despite standard treatment. It focuses on people with higher blood eosinophils (a type of white blood cell). If you smoke or used to smoke and have had at least 2 moderate or 1 severe flare-up in the past year, this study may be an option.
Philadelphia, PennsylvaniaAges 40–80 - NCT07190222RecruitingPhase 3
New medicine for COPD with frequent flare-ups
This study tests a new medicine called Lunsekimig for people with COPD that has frequent flare-ups and high eosinophil levels (a sign of inflammation). It aims to see if it can help control symptoms better than a placebo (a dummy treatment).
Media, PennsylvaniaAges 40–80 - NCT07177339RecruitingPhase 3
Testing depemokimab for COPD with type 2 inflammation
This study tests an early treatment called depemokimab for people with moderate to severe COPD who have a type of inflammation linked to high eosinophils. It aims to reduce flare-ups and improve breathing.
DuBois, PennsylvaniaAges 40–75 - NCT07082738RecruitingPhase 2
Study of AZD6793 for people with moderate to very severe COPD
This trial tests a new drug called AZD6793 for people with moderate to very severe COPD. It aims to see if the drug can help improve breathing and reduce flare-ups.
Smithfield, PennsylvaniaAges 40 years+ - NCT06961214RecruitingPhase 3
Depemokimab for COPD with type 2 inflammation
This study tests a new biologic medicine, given as an injection, to see if it can reduce flare-ups in adults with COPD who have a certain type of inflammation. It may help people who still have frequent exacerbations despite using their current inhalers.
DuBois, PennsylvaniaAges 40–80
COPD trials by city in Pennsylvania
Where these studies are running in Pennsylvania
Institutions with a site for the recruiting copd studies listed above.
- Temple University Hospital · 4 studies
- Clinical Research Associates of Central Pennsylvania · 3 studies
- Research Site · 3 studies
- GSK Investigational Site · 2 studies
- Thomas Jefferson University · 2 studies
- Clinical Research Associates of Central PA, LLC
- Copd01 50002
- DM Clinical Research - Philadelphia
What taking part in a copd study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
COPD trials in other states
Common questions
- Are there copd clinical trials in Pennsylvania?
- Yes. We're currently tracking 30 recruiting copd studies with a site in Pennsylvania, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a copd study in Pennsylvania?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Pennsylvania to take part?
- Not necessarily. These studies have a site in Pennsylvania, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a copd trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New copd studies open in Pennsylvania regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.