Clinical trials
COVID-19 Acute Respiratory Distress Syndrome clinical trials
Below are recruiting covid-19 acute respiratory distress syndrome clinical trials, each written for real people, not researchers. We’re tracking 17 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03963622Recruiting
Test of careful breathing support for severe lung distress
This study compares a more careful ventilation approach for people with severe lung breathing failure (ARDS). It aims to improve outcomes by using a specific strategy for how the ventilator controls breathing.
New York, New YorkAges 18 years+ - NCT04442191RecruitingPhase 2
Convalescent plasma for hospitalized COVID-19 patients over 40
This trial tests whether donated “recovered patient” plasma (antibodies from people who had COVID-19) can improve outcomes for people hospitalized with COVID-19. It focuses on patients early in their illness who need a small amount of oxygen.
Chicago, IllinoisAges 40 years+ - NCT04804943Recruiting
Testing an added breathing therapy for ARDS patients on ventilators
This pilot study tests NOA-001, a treatment given to people with ARDS (a serious lung condition) who are already on a breathing machine. It looks at whether the treatment can improve outcomes in ARDS caused by either non-COVID illnesses or COVID-19.
TokyoAges 16 years+ - NCT05123755RecruitingPhase 2
Testing a new medicine in hospitalized pneumonia patients needing oxygen
This Phase 2 trial tests an investigational medicine (given in increasing doses) for hospitalized people with pneumonia who need supplemental oxygen. It aims to see if the medicine is safe and potentially helps the pneumonia process in the early hospital period.
Newport Beach, CaliforniaAges 18 years+ - NCT05164744Recruiting
MRI study of heart tissue changes after COVID-19
This study uses a heart MRI to look for leftover (healing) changes in heart tissue after COVID-19. It may help researchers better understand what ongoing heart effects can happen after infection.
Brooklyn, New YorkAges 18 years+ - NCT05354141RecruitingPhase 3
Tested treatment with tiny lung particles for moderate to severe ARDS
This Phase 3 trial studies an “extracellular vesicle” treatment in people with moderate to severe ARDS, a serious lung breathing problem. The goal is to see whether the treatment can improve outcomes compared with standard care.
Phoenix, ArizonaAges 18–75 - NCT05562505Recruiting
Using ECMO to help you breathe, sit up, and come off a ventilator
This trial tests whether a heart-lung machine called venovenous ECMO can help people with severe breathing failure get less sedated, get extubated (have the breathing tube removed), and start moving. It’s for certain adults who are on a ventilator for a short time and have specific oxygenation problems.
Darlinghurst, New South WalesAges 18–65 - NCT06052436RecruitingPhase 1/Phase 2
Treg cell therapy for COVID-19 and acute respiratory distress
This trial tests a new cell therapy using Treg cells from thymic tissue to calm an overactive immune response in severe COVID-19 and ARDS. It aims to improve breathing and reduce inflammation.
Madrid, MadridAges 18–65 - NCT06402318Recruiting
Quick breath test for COVID, flu, and RSV
This study tests a breathalyzer device that quickly detects COVID-19, flu, and RSV from your breath. If you are already being tested for these viruses, you may join to see if this new method works as well as the usual swab test.
Fort Sam Houston, TexasAges 18–89 - NCT06807983Recruiting
Lung and heart ultrasound for breathing trouble in older adults
This trial tests whether using lung and heart ultrasound (LuCUS) can help emergency doctors better diagnose and treat shortness of breath in patients over 65. It aims to improve care for older adults with severe breathing problems.
ToulouseAges 65 years+ - NCT07051967Recruiting
Comparing recovery after ICU for pregnant and non-pregnant COVID-19 patients
This study looks at how COVID-19 and respiratory failure affect recovery after intensive care. It compares pregnant patients to non-pregnant patients to learn more about the long-term effects.
BerlinAges 18 years+ - NCT04369599Enrolling by invitation
Test chest vibration during ventilation for severe lung failure
This study looks at whether a special chest “vest” and related lung measurements can improve breathing in people with sudden severe lung failure who need a breathing machine. You may be eligible if you have ARDS and can safely use the vest during mechanical ventilation.
Atlanta, GeorgiaAges 18 years+ - NCT07413978RecruitingPhase 1/Phase 2
Stem cell injection for severe ARDS
This trial tests whether an injection of stem cells from umbilical cords can help people with severe ARDS (a type of lung failure) recover faster. It is for those who have not improved after standard treatment and whose ARDS is caused by an infection (not COVID-19).
Wuhan, HubeiAges 18–80 - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT04545424RecruitingPhase 2
Testing cooling treatment for severe lung failure in ICU patients
This trial tests whether therapeutic cooling (hypothermia) can improve outcomes in people with ARDS, a serious lung condition causing breathing failure. It may help by reducing harmful inflammation and lung injury, but eligibility is time-sensitive and requires ICU monitoring.
Los Angeles, CaliforniaAges 18–85 - NCT06631287RecruitingPhase 3
Testing baricitinib for persistent long COVID symptoms
This trial tests whether the anti-inflammatory drug baricitinib can improve persistent long COVID symptoms like brain fog, fatigue, and shortness of breath. You may qualify if you had COVID-19 at least 6 months ago and still have bothersome symptoms that affect your daily life.
Tucson, ArizonaAges 18 years+ - NCT05213000Recruiting
Exercise program study to boost vaccine immune response
This study looks at whether regular light-to-moderate exercise around the time of getting an mRNA COVID-19 vaccine can improve your immune response. It may help researchers understand how stress and exercise affect how well vaccines work.
Ames, IowaAges 18–64
Hear when a new COVID-19 Acute Respiratory Distress Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for covid-19 acute respiratory distress syndrome?
- Yes. Clin2 currently lists 17 recruiting covid-19 acute respiratory distress syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a covid-19 acute respiratory distress syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a covid-19 acute respiratory distress syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.