Clinical trials
Critical Care, Intensive Care clinical trials
Below are recruiting critical care, intensive care clinical trials, each written for real people, not researchers. We’re tracking 154 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06766461RecruitingPhase 4
Optimizing antibiotic dosing in ICU patients with septic shock
This trial checks if giving higher doses of beta-lactam antibiotics (a type of strong antibiotic) right from the start helps people in the ICU with septic shock. It aims to find the best dose to fight the infection quickly.
RotterdamAges 18 years+ - NCT07032987Recruiting
Improving sedation with a new care plan for ICU patients
This trial tests a new sedation protocol for adults in intensive care who need strong pain relief or sedation medicines. It aims to make sedation safer and more comfortable, and includes people on ECMO (a heart-lung machine) or a ventilator (breathing machine) for severe breathing problems.
London, LondonAges 18–100 - NCT05551325Recruiting
Resetting sleep timing for ICU patients to support recovery
This study tests a “sleep chronobundle,” a set of sleep and light-timing steps, to improve daily sleep-wake timing in people in the ICU on breathing or blood-pressure support. It also checks whether the body’s sleep rhythms are more aligned during critical illness and over time.
New Haven, ConnecticutAges 18 years+ - NCT06513130Recruiting
Checkup after ICU for adults 75 and older
This study looks at how well older adults (75+) do after leaving the intensive care unit. It will test a simple checkup done at discharge to see if it helps doctors plan better care.
StrasbourgAges 75 years+ - NCT06683781Recruiting
Breathing machine settings and weaning success study
This study looks at how breathing machine settings and monitoring can help predict if a patient will successfully come off the ventilator. It may help doctors choose better settings for patients who are ready to try breathing on their own.
Buenos AiresAges 18–100 - NCT03793257Recruiting
ECMO patient registry for adults in Australia and New Zealand
This is a research registry for adults who need a breathing and/or heart support machine called ECMO while in the hospital. It collects information to better understand who receives ECMO and how patients do over time.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT05298982Enrolling by invitation
Join a long-term follow-up study for ICU care
This study follows people who joined the TEAM Phase III trial to learn how ICU care affects health over the long term. Your participation helps researchers understand outcomes long after the initial treatment.
Camperdown, New South WalesAges 18 years+ - NCT06427265Recruiting
Recovery after ICU: a long-term study
This study follows people after they leave the ICU to see how they recover over time. It uses computer programs to find patterns and create early warning tools to help doctors spot problems sooner.
Guiyang, GuizhouAges 18–100 - NCT04608630RecruitingPhase 2
Preventing bone loss in ICU patients with anti-bone drugs
This Phase 2 study tests whether zoledronic acid or denosumab can prevent bone thinning in critically ill adults after staying in the ICU. It may help reduce the risk of future bone fractures if your body is at higher risk during and after critical illness.
Sydney, New South WalesAges 50 years+ - NCT04588311RecruitingPhase 3
Epoetin to improve outcomes in severe trauma ICU patients
This trial tests epoetin alfa (a blood-building medicine) to help reduce death and severe disability in critically ill trauma patients in the ICU. You may be considered if your ICU team expects a longer stay and the timing after injury is early.
Camperdown, New South WalesAges 18–75 - NCT06370338Recruiting
Expert views on cardiothoracic critical care training
This study interviews experts in cardiothoracic critical care to understand what training is needed. It helps improve how doctors learn to care for patients after heart or chest surgery.
Columbus, OhioAges Any age - NCT07457554Recruiting
Can respiratory quotient help ICU patients on ventilators?
This study looks at whether using a simple measurement called the respiratory quotient (a sign of how your body is using fuel) can help doctors make better decisions for patients on a breathing machine in the ICU. It may lead to safer, more personalized care.
Poznan, WielkopolskaAges 18–85 - NCT06799910Recruiting
Optimizing fluid balance with bioelectrical impedance during dialysis in ICU
This trial tests a method to better manage fluid levels in critically ill patients who are receiving a type of dialysis (CVVH) for kidney failure. It uses a device (bioelectrical impedance) to measure fluid in the body, which may help doctors give the right amount of fluids more safely.
SalouëlAges 18 years+ - NCT03216785Recruiting
Study of long-term health after ICU stays
This study follows people admitted to a medical intensive care unit to understand long-term problems after critical illness. It may help researchers better identify who is at risk and how to improve recovery after an ICU stay.
SeoulAges 20 years+ - NCT04176094Recruiting
Trial of ICU overnight resident scheduling plans
This study tests whether changing how ICU residents are scheduled for overnight shifts affects training and ICU operations. It looks at participating adult ICU patients and the residents and staff who work overnight during the study periods.
Toronto, OntarioAges 18 years+ - NCT05295862Recruiting
Stroke registry for adults after acute stroke
This study enrolls adults who are admitted to the hospital for a sudden (acute) stroke. It mainly collects information about your care and recovery to help improve stroke treatment in the future.
Giessen, HesseAges 18 years+ - NCT05357170Recruiting
Testing gut bacteria changes after severe ICU illnesses
This study looks at changes in the microbiome (gut bacteria) in adults after serious ICU illnesses like sepsis, major trauma, or open heart/abdominal surgery. It may help researchers understand why recovery can be harder in some people and guide future treatments.
Gainesville, FloridaAges 18–110 - NCT05415332Recruiting
Tracking outcomes for cardiogenic shock in ICU
This study looks at how people with cardiogenic shock (or very low blood pressure from heart causes) do after treatment in a specialized cardiovascular ICU. It also examines whether care by heart critical-care specialists affects outcomes.
SeoulAges 19 years+ - NCT06206759Recruiting
Vitamin C for triglyceride levels in ICU patients
This trial looks at whether giving vitamin C through an IV can help lower triglyceride levels in patients in the intensive care unit. It compares patients who received vitamin C with similar patients who did not.
Kfar SabaAges 18–99 - NCT06735898Recruiting
A combined therapy for recovery after intensive care
This trial tests a combination of CYTOFLAVIN (given as an IV and later as a pill) to help people with long-term symptoms after spending time in the ICU. It aims to improve muscle weakness, breathing, swallowing, and energy levels during later stages of rehabilitation.
Yekaterinburg, Sverdlovsk OblastAges 18 years+ - NCT06927037Recruiting
Physical therapy for very premature babies in the NICU
This study tests whether immersive physical therapy (special hands-on activities) helps babies born very early (before 29 weeks) grow and develop better while in the NICU. It may help your baby's movement and strength.
Chapel Hill, North CarolinaAges birth–99 years - NCT06940219Recruiting
Comparing delayed vs. rapid intubation in emergencies
This trial tests whether delaying medication to start breathing support (by waiting 60 seconds after sedation) is safer for critically ill adults needing emergency intubation. Standard practice is to give sedation then immediately insert the tube.
Leipzig, SaxonyAges 18 years+ - NCT06990295Recruiting
Ultrasound spleen stimulation for sepsis shock
This trial tests if using focused ultrasound to stimulate the spleen can reduce inflammation in septic shock. It may help patients in the ICU who need strong blood pressure support.
Wuhu, AnhuiAges 18 years+ - NCT07239206Recruiting
Serious game for ICU nurses on temperature management
This study tests whether a serious game (an educational game) can help critical care nurses learn more about targeted temperature management (cooling or warming the body to protect the brain) and improve their ability to notice and react to patient changes. You would play the game and take tests before and after to see if it works.
Taipei, TaipeiAges 20 years+
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Common questions
- Are there clinical trials for critical care, intensive care?
- Yes. Clin2 currently lists 154 recruiting critical care, intensive care studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critical care, intensive care trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critical care, intensive care trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.