Clinical trials
Critically Ill clinical trials
Below are recruiting critically ill clinical trials, each written for real people, not researchers. We’re tracking 336 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07307066Recruiting
Ventilation feedback study for lung protection in ARDS
This study tests a computer system that gives real-time breathing machine advice to help protect the lungs of patients with severe lung injury (ARDS). It may help doctors adjust the ventilator settings to cause less damage.
Qujing, YunnanAges 18–75 - NCT07093125Recruiting
Rehabilitation for ICU patients on a breathing machine
This trial is studying rehabilitation practices for people in the ICU who need a breathing machine (ventilator) for at least 48 hours. It aims to improve recovery and care for critically ill patients.
Genova, ItalyAges 16–100 - NCT07877350Recruiting
Breathing effort and breathlessness in ICU patients on a ventilator
This study looks at how the effort patients make to breathe relates to feelings of breathlessness while they are on a breathing machine in the intensive care unit. It may help doctors better manage breathing support to reduce discomfort.
HeraklionAges 18 years+ - NCT07854730Recruiting
Lung treatment with positioning for pneumonia in ventilated patients
This study tests whether using a breathing bag to inflate the lungs while changing body position can improve oxygen levels in patients with pneumonia who are on a breathing machine. It may help clear mucus and improve breathing.
CairoAges 40–60 - NCT03470467Recruiting
ICU study of a reversible brain swelling condition
This trial looks at Posterior Reversible Encephalopathy Syndrome (PRES) in adults in the ICU. It may help doctors better understand and manage a condition that can cause seizures, confusion, headaches, and vision problems, and that typically shows specific changes on brain scans.
Le ChesnayAges 18 years+ - NCT04541862Recruiting
ICU patient information database for adults
This trial collects and studies health information from people who are critically ill and admitted to an intensive care unit. It may help doctors learn how to better care for ICU patients in the future.
TaipeiAges 20 years+ - NCT03457831Recruiting
Check a treatment approach for prolonged seizure emergencies
This trial is for adults in the intensive care unit who are having seizures that last at least 5 minutes or keep coming back without fully recovering. It tests a study approach for managing a dangerous seizure emergency and may help doctors improve care for critically ill patients.
AngoulêmeAges 18 years+ - NCT03793257Recruiting
ECMO patient registry for adults in Australia and New Zealand
This is a research registry for adults who need a breathing and/or heart support machine called ECMO while in the hospital. It collects information to better understand who receives ECMO and how patients do over time.
Canberra, Australian Capital TerritoryAges 18 years+ - NCT04722939Recruiting
Testing brain function outcomes after ICU kidney failure treatment
This trial studies how treating severe kidney injury in the ICU may affect patients’ brain and thinking function over time. It compares measurements of brain activity and function after starting kidney replacement therapy.
Kingston, OntarioAges 18 years+ - NCT01913938Recruiting
Testing treatment for severe inflammation in very ill adults
This trial looks at how to treat a severe, whole-body immune overreaction (“hemophagocytosis”) in adults who are critically ill. You might be considered if blood counts are low (white blood cells and platelets) and if you are already receiving a growth-factor medicine (rhG-CSF).
UlmAges 18–90 - NCT05191381Recruiting
Immune treatment using exosome therapy for severe COVID-19
This trial tests whether immune-supporting treatment made from exosomes can help people with critically severe COVID-19 and lung damage. If you qualify, you may receive this therapy as part of the study to see if it improves outcomes.
UlmAges 18–90 - NCT05860894Recruiting
Study of new ICU atrial fibrillation
This trial looks at people who develop a new irregular heart rhythm called atrial fibrillation while in the intensive care unit (ICU). It tests an approach to help with that condition after critical illness, aiming to improve outcomes for those affected.
BesançonAges 18 years+ - NCT06362525Recruiting
Episodes of Disconnected Consciousness in Emergency Patients
This study looks at brief episodes of being disconnected from your surroundings among very ill emergency patients. Researchers want to see how often this happens and what it means for recovery.
LiègeAges 18 years+ - NCT01068990Recruiting
Testing how to identify pneumonia germs in ICU patients
This study looks at how well doctors can detect and identify the cause of new pneumonia in people in the medical intensive care unit (ICU). It may help improve how pneumonia is diagnosed and treated in critically ill patients.
SeoulAges 16 years+ - NCT06369818Recruiting
Heart output measurement in shock patients on life support
This study tests if a new way of measuring heart function (using sound waves and breath analysis) works well in patients who are in severe heart failure and need a heart-lung machine. It might help doctors better monitor patients after heart surgery.
MünsterAges 18 years+ - NCT06452966Recruiting
Traditional Chinese medicine for organ failure in ICU
This trial is studying whether adding traditional Chinese medicine (TCM) to standard care can help patients in the surgical ICU recover from organ failure. It looks at how TCM might support your body's organs during critical illness.
TaichungAges 20 years+ - NCT07837128Recruiting
Gentle breathing support in intensive care
This trial tests two ways of using a breathing machine (ventilator) in the ICU. One method is more gentle on the lungs, and the goal is to see if it helps patients recover faster.
Amsterdam, NLAges 18 years+ - NCT06471400Recruiting
Making clinical trial consent easier for legal representatives
This trial is designed to improve how legally authorized representatives (people who make medical decisions for patients) understand and agree to join clinical studies. The goal is to see if simpler consent processes help representatives feel more comfortable giving permission.
Freiburg im BreisgauAges 18–100 - NCT07817550Enrolling by invitation
Predicting sudden health declines with wearable monitors
This study uses wearable devices and other monitoring tools to see if they can predict when a patient might suddenly get worse within the next 72 hours. By participating, you may help develop early warning systems that could lead to faster medical help.
New York, New YorkAges 18–90 - NCT07802379Recruiting
Tube feeding tolerance with different blood pressure medications in the intensive care unit
This study looks at how critically ill patients on a breathing tube and receiving nutrition through a tube tolerate their feeding, depending on the dose of medications given to manage their blood pressure. It aims to see if feeding works well while patients are on these medications.
IstanbulAges 18 years+ - NCT07787312Recruiting
Ultrasound for swallowing and muscle loss in intensive care patients
This study uses ultrasound to check the muscles that help you swallow and move. It aims to see if measuring these muscles can predict swallowing problems and muscle loss after being on a breathing machine.
Madrid, MadridAges 18 years+ - NCT02893462Recruiting
Collecting health and signal data from ICU patients
This trial sets up a way to collect and store physiological readings (like vital-sign data) from adults in the intensive care unit. It aims to improve how doctors understand and monitor critically ill patients over time.
BrestAges 18 years+ - NCT07737353Recruiting
Education for families of ICU patients with tracheostomy
This study tests whether a structured education program for family members of ICU patients who need a tracheostomy helps them feel more prepared and less stressed. You would be asked to attend training sessions and fill out some questionnaires.
Giresun, GiresunAges 18 years+ - NCT07740304Recruiting
Blood flow test to predict survival in sepsis patients
This study checks if a simple blood flow measurement can help predict which patients with sepsis are at higher risk of dying within 28 days. The goal is to see if this test can guide treatment decisions in the ICU.
Edirne, MerkezAges 18 years+
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Common questions
- Are there clinical trials for critically ill?
- Yes. Clin2 currently lists 336 recruiting critically ill studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a critically ill trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a critically ill trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.