Clinical trials
Crohn's Disease, Active clinical trials
Below are recruiting crohn's disease, active clinical trials, each written for real people, not researchers. We’re tracking 195 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06750731Recruiting
IV vs. shot vedolizumab for IBD with remote check-ins
This study compares two ways of taking the IBD medicine vedolizumab (injecting under the skin versus through an IV line). You'll use a smartphone app to report your symptoms, so you can participate from home and help doctors learn which option works better.
New Orleans, LouisianaAges 18 years+ - NCT07632573RecruitingPhase 1
Safety Study of BDHK-2009 Tablets in Healthy Adults
This is an early-stage safety study testing a new experimental tablet called BDHK-2009 in healthy volunteers with no major illnesses. Researchers want to make sure the drug is safe and well-tolerated before testing it in people with medical conditions.
Hangzhou, ZhejiangAges 18–55 - NCT06774079RecruitingPhase 4
GLP-1 drug and diet study for Crohn's disease patients
This study tests a drug that helps with weight loss and blood sugar (called a GLP-1 receptor agonist) combined with a special diet to see if it can improve symptoms in people with mild Crohn's disease. You may join if you have Crohn's, a BMI of 27 or higher, and are already on a stable dose of a TNF blocker.
Miami, FloridaAges 18 years+ - NCT07385131Recruiting
Steroid before infliximab for inflammatory bowel disease
This study tests whether giving a steroid (dexamethasone) before an infliximab infusion can prevent allergic reactions in people with moderate-to-severe Crohn's disease or ulcerative colitis. If you qualify, you will receive either the steroid or a placebo before your infliximab treatment.
Hangzhou, ZhejiangAges 14–80 - NCT04010526RecruitingPhase 2
Local treatment for Crohn’s fistulas using your own fat cells
This Phase 2 trial studies whether a local injection of fat-derived cells (made from your own tissue) can improve difficult Crohn’s disease fistulas around the anus. It’s designed for people whose Crohn’s fistulas have not responded to usual treatments.
Marseille, PACAAges 18 years+ - NCT06606808RecruitingPhase 1/Phase 2
Imaging risankizumab in inflammatory bowel disease
This trial tests a new imaging method using a special dye (risankizumab-800CW) to see how risankizumab, a medicine for inflammatory bowel disease, works in the bowel. The goal is to better understand the medicine's effects and help doctors tailor treatments.
GroningenAges 18 years+ - NCT07033208Recruiting
Testing a wireless thermal capsule for the digestive tract
This study tests a new wireless capsule that you swallow, like a pill, to measure temperature inside your digestive tract. It is for healthy volunteers to see if the device is safe and works well.
Boston, MassachusettsAges 18–75 - NCT07113522RecruitingPhase 2
Study of new therapies for Crohn's and colitis
This trial tests new therapies for people with moderate to severe Crohn's disease or ulcerative colitis. It may help if your standard treatments aren't working well enough.
Birmingham, AlabamaAges 18–80 - NCT06657001Enrolling by invitation
Personalized nutrition study for gut health
This study uses information from your gut bacteria (microbiome) to create personalized nutrition advice. It is for people with gut conditions like IBD, IBS, or celiac disease, as well as healthy volunteers.
Rochester, MinnesotaAges 18 years+ - NCT07216014RecruitingPhase 4
IL-23 antibody for inflammatory bowel disease
This trial tests a new antibody drug (IL-23 inhibitor) for people with Crohn's disease or ulcerative colitis. It aims to see if the drug is safe and effective. You may be able to join if you have moderate to severe disease and have not had certain bowel surgeries or infections.
Guangzhou, GuangdongAges 18–65 - NCT06351124RecruitingPhase 1/Phase 2
Beta-hydroxybutyrate for active Crohn's disease when starting new therapy
This study tests whether a natural substance called beta-hydroxybutyrate (BHB) can help treat active Crohn's disease when you start a new prescription therapy. It aims to see if adding BHB is safe and practical.
Austin, TexasAges 18 years+ - NCT06587646Recruiting
Virtual reality for perianal Crohn's surgery
This trial is testing whether using virtual reality (VR) technology can help doctors better plan surgery for people with Crohn's disease around the bottom. It aims to improve how fistulas and abscesses are managed.
NottinghamAges 18–75 - NCT04617184Recruiting
Join an inflammatory bowel disease registry and sample bank
This study asks people with known or suspected inflammatory bowel disease to enroll in a registry and biorepository. It helps researchers better understand the condition using health information and stored biological samples.
Austin, TexasAges 18–100 - NCT06956703Recruiting
Nottingham IBD study testing new treatments
This study looks at people with active Crohn's disease or ulcerative colitis starting a new type of medication (anti-TNF, ustekinumab, upadacitinib, or vedolizumab), as well as people without IBD having a routine colonoscopy. It aims to collect information to better understand how these treatments work.
Nottingham, NottinghamshireAges 16 years+ - NCT04924270RecruitingPhase 2
Capsule stool transfer for newly diagnosed inflammatory bowel or joint disease
This Phase 2 study tests whether taking capsule stool (FMT) is safe and can help people who are newly diagnosed and haven’t started the usual medicines yet. Participants will also start the standard first-line treatment for their condition, and the study will compare safety and outcomes.
OdenseAges 18–75 - NCT06895252Recruiting
Fecal transplant and diet for new ulcerative colitis
This study tests whether a combination of fecal transplant (transferring healthy stool into your gut) and dietary changes can help control inflammation in people recently diagnosed with active ulcerative colitis. It may offer a new treatment option before starting stronger medications.
Kochi, KeralaAges 18–75 - NCT07519850Recruiting
How Perianal Disease Affects Sexual Health and Quality of Life
This study explores how chronic perianal conditions—like anal fistulas or pilonidal disease—affect patients' sexual function and relationships. Researchers will ask you to complete surveys about your symptoms and sexual health to better understand this impact and help future patients.
Thessaloniki, ThessalonikiAges 18 years+ - NCT07686406Recruiting
IBD biomarker discovery study
This study collects blood, stool, tissue, and health information from people with inflammatory bowel disease (IBD), their relatives, and healthy volunteers to find patterns that may help diagnose or treat IBD better in the future.
Guangzhou, GuangdongAges 14 years+ - NCT06211400Recruiting
Vibration Exercise for Crohn's Disease Response
This study tests whether gentle whole-body vibration exercise can help people with mild to moderate Crohn's disease feel better. You will do short vibration sessions at a research center over several weeks.
Hatfield, UKAges 18–65 - NCT04760964Recruiting
Testing blood markers in active Crohn’s and ulcerative colitis
This study looks for specific body signals (called mitochondrial “DAMPs”) that may reflect active inflammation in Crohn’s disease and ulcerative colitis. It also checks how these markers relate to what doctors see during colonoscopy or flexible scope exams, to help understand inflammation and potentially guide future care.
DundeeAges Any age - NCT07710287Recruiting
Using a protein test to measure inflammation in IBD
This study looks at a protein called claudin 2 in tissue samples from people with inflammatory bowel disease (IBD). The goal is to see if it can help doctors tell whether inflammation is active or inactive. This could lead to a more accurate way to check disease activity.
San Donato Milanese, MiAges 18 years+ - NCT05579392Recruiting
Bright light therapy for gut inflammation in Crohn’s or colitis
This trial studies whether daily bright light can improve gut barrier “leakiness” and reduce inflammation in adults with Crohn’s disease or ulcerative colitis. It compares bright light versus dim light in a crossover design, meaning you may receive both.
Chicago, IllinoisAges 18 years+ - NCT07160231RecruitingPhase 4
Lowering dose of JAK inhibitors for rheumatoid arthritis or psoriatic arthritis
This trial tests if reducing the dose of a JAK inhibitor can keep your inflammatory arthritis under control. If you have rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis and are in a stable remission, you may be able to take a lower dose.
Nijmegen, GelderlandAges 16 years+ - NCT05230173Recruiting
Treat to endoscopic remission in inflammatory bowel disease
This study tests whether switching to a different treatment for inflammatory bowel disease (IBD) can achieve healing of the gut lining. It is for people whose symptoms are under control but who still have significant inflammation in their bowel.
Scottsdale, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for crohn's disease, active?
- Yes. Clin2 currently lists 195 recruiting crohn's disease, active studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn's disease, active trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn's disease, active trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.