Clinical trials
Crohn's Disease, Active clinical trials
Below are recruiting crohn's disease, active clinical trials, each written for real people, not researchers. We’re tracking 199 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06211400Recruiting
Vibration Exercise for Crohn's Disease Response
This study tests whether gentle whole-body vibration exercise can help people with mild to moderate Crohn's disease feel better. You will do short vibration sessions at a research center over several weeks.
Hatfield, UKAges 18–65 - NCT07710287Recruiting
Using a protein test to measure inflammation in IBD
This study looks at a protein called claudin 2 in tissue samples from people with inflammatory bowel disease (IBD). The goal is to see if it can help doctors tell whether inflammation is active or inactive. This could lead to a more accurate way to check disease activity.
San Donato Milanese, MiAges 18 years+ - NCT05579392Recruiting
Bright light therapy for gut inflammation in Crohn’s or colitis
This trial studies whether daily bright light can improve gut barrier “leakiness” and reduce inflammation in adults with Crohn’s disease or ulcerative colitis. It compares bright light versus dim light in a crossover design, meaning you may receive both.
Chicago, IllinoisAges 18 years+ - NCT07160231RecruitingPhase 4
Lowering dose of JAK inhibitors for rheumatoid arthritis or psoriatic arthritis
This trial tests if reducing the dose of a JAK inhibitor can keep your inflammatory arthritis under control. If you have rheumatoid arthritis, psoriatic arthritis, or axial spondyloarthritis and are in a stable remission, you may be able to take a lower dose.
Nijmegen, GelderlandAges 16 years+ - NCT03901235RecruitingPhase 1/Phase 2
Stem cell injections for Crohn’s lesions that won’t heal
This study tests injections of stem cells placed directly into Crohn’s affected tissue. It may help people whose Crohn’s disease lesions have not responded to standard medicines and biologic therapies.
Liège, LiègeAges 18 years+ - NCT06663332RecruitingPhase 3
Long-term study of guselkumab in children who previously took it
This study is a long-term follow-up for children who have already finished an earlier study of guselkumab, a medicine for skin conditions like psoriasis. It looks at whether staying on the medicine continues to be safe and helpful over time.
Atlanta, GeorgiaAges 3 years+ - NCT06698601Recruiting
Wild blueberries for colitis inflammation
This study tests whether eating wild blueberries can help reduce inflammation in people with Crohn's disease or ulcerative colitis. You would eat wild blueberries during your hospital stay and have a colonoscopy to see how your gut is doing.
Bamberg, BavariaAges 18 years+ - NCT07724990Recruiting
Probiotic for gut health in mild-to-moderate colitis
This trial tests a specific probiotic (a type of beneficial bacteria) to see if it can help people with mild to moderate ulcerative colitis by improving the balance of gut microbes. It may be an option if you have not used many advanced treatments before.
Roma, RMAges 18–80 - NCT07654751RecruitingPhase 4
Study of Tremfya in breast milk of breastfeeding women
This study measures how much Tremfya (guselkumab) gets into breast milk for women who are already taking it for conditions like psoriasis or arthritis and choose to breastfeed. It helps understand if the drug passes to the baby.
Chapel Hill, North CarolinaAges 18 years+ - NCT06997965RecruitingPhase 4
Mirikizumab for Crohn's with inflammatory strictures
This study tests a medication called mirikizumab to see if it can help people with Crohn's disease who have narrowing (strictures) in the small intestine caused by inflammation. The goal is to improve symptoms like belly pain after eating and to possibly reduce the narrowing without needing surgery.
Orlando, FloridaAges 18 years+ - NCT06997055Recruiting
Study of Steqeyma® biosimilar in Crohn's and psoriasis
This study follows people with Crohn's disease or plaque psoriasis who are switching from the reference Ustekinumab to a biosimilar (Steqeyma®). It aims to see how well the biosimilar works in real-world settings.
AmiensAges 18 years+ - NCT06906445Recruiting
Fecal transplant and diet changes for ulcerative colitis
This trial tests if a fecal transplant combined with dietary changes can help control symptoms in people with active ulcerative colitis who haven't responded well to standard treatments or advanced therapies.
Kochi, KeralaAges 18–75 - NCT06862843Recruiting
Family eating habits and chronic inflammation study
This study looks at how eating habits and family health history relate to chronic inflammatory conditions like Crohn's disease, ulcerative colitis, and juvenile idiopathic arthritis. It aims to understand these links by studying families with a child or adult affected by these conditions, as well as healthy families.
Florence, ItalyAges Any age - NCT06670638Recruiting
New test for crohn's disease in people with a permanent ileostomy
This study aims to develop a new way to measure inflammation and symptoms in people with Crohn's disease who have a permanent ileostomy. Participants will undergo a routine ileoscopy and answer questions to help create better tools for future clinical trials.
Rochester, MinnesotaAges 18 years+ - NCT06495658Recruiting
Prebiotics for ulcerative colitis symptoms
This trial tests whether a prebiotic supplement can improve symptoms of ulcerative colitis. It may be a good option for people with active symptoms who are already on stable medications.
Los Angeles, CaliforniaAges 18–85 - NCT05974280Recruiting
Stem cell treatment for complex anal fistulas
This trial compares two types of stem cell treatments to help heal complex anal fistulas (abnormal tunnels near the anus). You may be eligible if your Crohn’s-related disease is mostly controlled and the fistula has not fully healed with standard treatments.
Nantes, NantesAges 18 years+ - NCT05660746RecruitingPhase 2/Phase 3
Infliximab dose tailored to control Crohn’s inflammation
This trial tests a more precise way to start infliximab (a Crohn’s medicine) and adjust dosing based on how your body responds. It aims to better control Crohn’s inflammation early and keep it under control.
Los Angeles, CaliforniaAges 6–22 - NCT05421455Recruiting
Early vs delayed surgery for Crohn’s bowel narrowing
This study compares two timing choices for surgery in people with Crohn’s disease who have bowel narrowing (strictures) causing blockage symptoms. The goal is to see whether operating earlier leads to better control of symptoms and inflammation when other treatments haven’t worked.
Nanjing, JiangsuAges 18–60 - NCT05230173Recruiting
Treat to endoscopic remission in inflammatory bowel disease
This study tests whether switching to a different treatment for inflammatory bowel disease (IBD) can achieve healing of the gut lining. It is for people whose symptoms are under control but who still have significant inflammation in their bowel.
Scottsdale, ArizonaAges 18 years+ - NCT05169593RecruitingPhase 4
Prevent Crohn’s return after surgery: endoscopy-guided vs standard medicine
This study compares two ways to choose biologic (targeted) medicines after Crohn’s surgery to help stop Crohn’s from coming back in the bowel. It may help you avoid or delay repeat inflammation by adjusting treatment based on endoscopy findings.
Antwerp, AntwerpenAges 18–80 - NCT03256240Recruiting
Two surgical options for Crohn’s bowel resection
This trial compares two ways of reconnecting the bowel after surgery in people with Crohn’s disease that affects the small intestine and/or colon. It aims to see which reconnection method works better after the initial surgery, even if you’re on Crohn’s medicines before the operation.
Boston, MassachusettsAges 18–90 - NCT07691138RecruitingPhase 4
Stopping acid-reducing pills in stable IBD
This study tests whether it is safe to stop taking acid-reducing pills (PPIs) for people with inactive IBD. If you have been on a PPI for over 6 months and your IBD is stable, you may be able to join.
NottinghamAges 16 years+ - NCT06064864Recruiting
Switching Infliximab from IV to Subcutaneous for Crohn's
This study tests whether switching from an IV infliximab to a subcutaneous (under-the-skin) version is safe and works well for people with moderate to severe Crohn's disease. It's for people who have never used a biologic and need a new treatment option.
SeoulAges 18–100 - NCT07305454Recruiting
Teaching exercise habits for Crohn's and colitis
This study tests whether structured education sessions about exercise can help people with Crohn's or colitis be more active. It looks at how this education affects your physical activity levels and overall health.
ToulouseAges 18–100
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Common questions
- Are there clinical trials for crohn's disease, active?
- Yes. Clin2 currently lists 199 recruiting crohn's disease, active studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn's disease, active trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn's disease, active trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.