Clinical trials
Crohn’s disease clinical trials
A type of inflammatory bowel disease causing inflammation of the digestive tract. We’re tracking 334 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04178408Recruiting
IBD family and neighborhood health registry study
This study builds a health registry for people with inflammatory bowel disease (IBD) and compares them with healthy family and neighborhood controls. It may help researchers better understand IBD in sub-Saharan African communities.
HarareAges Any age - NCT05633706Recruiting
Testing a capsule to study gut bacteria in the small intestine
This study tests the SIMBA capsule to learn how gut bacteria (dysbiosis) relate to digestive conditions. It may help researchers better understand these conditions and how the capsule can be used safely.
Calgary, AlbertaAges 18–80 - NCT05653011Recruiting
Study outcomes in people with inflammatory bowel disease
This study looks at what factors help predict how inflammatory bowel disease (IBD) may progress over time. You may be able to join if you are an adult with IBD and fit one of the study groups based on whether you have used TNF-blocking medicines before.
Seongnam-si, Gyeonggi-doAges 18 years+ - NCT05722236Recruiting
Peer support program to help people manage stress from IBD
This trial tests a “peer-to-peer” support program to help adults with inflammatory bowel disease (IBD) manage psychological distress (stress and emotional strain). It may help you cope better during major life or treatment changes related to IBD.
Halifax, N.S.Ages 18–99 - NCT06065228Recruiting
Tracking treatment progress in children with IBD
This study looks at a new way to measure how well treatment is working in children with inflammatory bowel disease (IBD). It uses a special eye test called pupillometry, which is painless and non-invasive, to see if it can help doctors adjust treatment earlier.
Washington D.C., District of ColumbiaAges 6–21 - NCT06774079RecruitingPhase 4
GLP-1 drug and diet study for Crohn's disease patients
This study tests a drug that helps with weight loss and blood sugar (called a GLP-1 receptor agonist) combined with a special diet to see if it can improve symptoms in people with mild Crohn's disease. You may join if you have Crohn's, a BMI of 27 or higher, and are already on a stable dose of a TNF blocker.
Miami, FloridaAges 18 years+ - NCT07532213Recruiting
Real-world outcomes of guselkumab for ulcerative colitis or Crohn's disease
This study tracks how well guselkumab (a biologic medication that blocks IL-23, a protein that drives inflammation) works for moderate-to-severe ulcerative colitis or Crohn's disease in everyday clinical practice. Researchers want to understand long-term benefits and safety in real patients.
BernAges 18 years+ - NCT07593352Recruiting
Kidney Health in Inflammatory Bowel Disease Patients
This study compares kidney function between people with inflammatory bowel disease (IBD) and those without it. Researchers want to understand if IBD affects the kidneys and why, which could help protect kidney health in IBD patients.
Warsaw, WarszawaAges 18–80 - NCT07385131Recruiting
Steroid before infliximab for inflammatory bowel disease
This study tests whether giving a steroid (dexamethasone) before an infliximab infusion can prevent allergic reactions in people with moderate-to-severe Crohn's disease or ulcerative colitis. If you qualify, you will receive either the steroid or a placebo before your infliximab treatment.
Hangzhou, ZhejiangAges 14–80 - NCT04010526RecruitingPhase 2
Local treatment for Crohn’s fistulas using your own fat cells
This Phase 2 trial studies whether a local injection of fat-derived cells (made from your own tissue) can improve difficult Crohn’s disease fistulas around the anus. It’s designed for people whose Crohn’s fistulas have not responded to usual treatments.
Marseille, PACAAges 18 years+ - NCT06606808RecruitingPhase 1/Phase 2
Imaging risankizumab in inflammatory bowel disease
This trial tests a new imaging method using a special dye (risankizumab-800CW) to see how risankizumab, a medicine for inflammatory bowel disease, works in the bowel. The goal is to better understand the medicine's effects and help doctors tailor treatments.
GroningenAges 18 years+ - NCT06636032RecruitingPhase 1/Phase 2
Stem cells for Crohn's fistula treatment
This trial tests whether injecting donated stem cells into complex anal fistulas can help heal them in people with Crohn's disease. You may qualify if you have a fistula that hasn't improved with standard treatments.
ToulouseAges 18 years+ - NCT07033208Recruiting
Testing a wireless thermal capsule for the digestive tract
This study tests a new wireless capsule that you swallow, like a pill, to measure temperature inside your digestive tract. It is for healthy volunteers to see if the device is safe and works well.
Boston, MassachusettsAges 18–75 - NCT07219537Recruiting
Imaging the lower gut with a new capsule
This trial tests a new type of camera capsule that takes pictures of the lower part of your digestive tract. It may be an option for people who are healthy or have Lynch Syndrome and have had a recent normal colonoscopy.
Boston, MassachusettsAges 18–75 - NCT07113522RecruitingPhase 2
Study of new therapies for Crohn's and colitis
This trial tests new therapies for people with moderate to severe Crohn's disease or ulcerative colitis. It may help if your standard treatments aren't working well enough.
Birmingham, AlabamaAges 18–80 - NCT06657001Enrolling by invitation
Personalized nutrition study for gut health
This study uses information from your gut bacteria (microbiome) to create personalized nutrition advice. It is for people with gut conditions like IBD, IBS, or celiac disease, as well as healthy volunteers.
Rochester, MinnesotaAges 18 years+ - NCT07216014RecruitingPhase 4
IL-23 antibody for inflammatory bowel disease
This trial tests a new antibody drug (IL-23 inhibitor) for people with Crohn's disease or ulcerative colitis. It aims to see if the drug is safe and effective. You may be able to join if you have moderate to severe disease and have not had certain bowel surgeries or infections.
Guangzhou, GuangdongAges 18–65 - NCT07195123Recruiting
Testing the SMART IBD app for kids with IBD
This study tests whether a smartphone app called SMART IBD can help children with IBD take their medications more consistently. It is for children who are currently missing more than 1 in 7 doses of their daily or weekly IBD medication.
Cincinnati, OhioAges 13–17 - NCT00001184Recruiting
Studying the immune system in Crohn's and colitis
This study collects blood and tissue samples to better understand how the immune system behaves in people with inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis. It aims to advance research rather than test a specific new treatment, and it also enrolls healthy volunteers for comparison.
Bethesda, MarylandAges 1 day–75 years - NCT04014413Recruiting
Fecal transplant for gut and immune-related conditions
This trial studies whether fecal microbiota transplantation (FMT)—a medical procedure using stool from a screened donor to restore gut bacteria—can improve safety and outcomes for people with certain bowel, immune, and metabolic conditions. It may help if your symptoms are thought to be related to an unhealthy gut microbiome, though eligibility is broad and depends on specific safety factors.
Hong Kong, ShatinAges Any age - NCT06351124RecruitingPhase 1/Phase 2
Beta-hydroxybutyrate for active Crohn's disease when starting new therapy
This study tests whether a natural substance called beta-hydroxybutyrate (BHB) can help treat active Crohn's disease when you start a new prescription therapy. It aims to see if adding BHB is safe and practical.
Austin, TexasAges 18 years+ - NCT04960826Recruiting
Study of an environmental risk factor in Crohn’s
This study looks at how an environmental factor may be linked to Crohn’s disease, especially around the time you need certain bowel surgery. Your experience may help researchers understand risk and how it relates to your gut health.
LilleAges 25–60 - NCT06124287Recruiting
Can MRI predict Crohn's relapse after stopping biologics?
This study looks at whether MRI scans can predict when Crohn's disease will come back after stopping biologic medications. If you are in remission and recently stopped a biologic, researchers want to see if your MRI results can help understand your risk of relapse.
LondonAges 16 years+ - NCT06581042Recruiting
Study of upadacitinib in adults with IBD in Belgium
This study looks at how adults with Crohn's disease or ulcerative colitis are doing after taking upadacitinib (Rinvoq) for at least 12 months. It helps doctors understand treatment patterns and outcomes in real-world settings.
Bonheiden, AntwerpenAges 18 years+
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Common questions
- Are there clinical trials for crohn’s disease?
- Yes. Clin2 currently lists 334 recruiting crohn’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.