Clinical trials
Crohn’s disease clinical trials
A type of inflammatory bowel disease causing inflammation of the digestive tract. We’re tracking 334 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07441447Recruiting
Muscle strength and mass in inflammatory bowel disease
This study looks at muscle strength and muscle mass in people with inflammatory bowel disease (IBD), such as Crohn's disease or ulcerative colitis. It aims to understand how IBD affects muscles, which can help improve patient care.
Sakarya, AdapazarıAges 18 years+ - NCT07352995Enrolling by invitation
Gut temperature study during colonoscopy
This study uses a special probe to measure temperature inside the colon during a routine colonoscopy. It may help researchers understand conditions like IBD, Crohn's disease, and ulcerative colitis.
Boston, MassachusettsAges 18 years+ - NCT06953791RecruitingPhase 2
Comparing two treatments for Crohn's disease flare-ups
This trial compares a steroid called prednisolone to a special diet (aCDED with PEN) for treating Crohn's disease flare-ups. It aims to see which approach helps improve quality of life.
TübingenAges 18 years+ - NCT06972901Recruiting
Preventing Crohn's recurrence after surgery using stool tests
This trial tests if checking a stool marker (fecal calprotectin) early after surgery can guide treatment with ustekinumab to prevent Crohn's disease from coming back. It's for people who had certain bowel surgery and have at least one risk factor for recurrence.
AmiensAges 18 years+ - NCT05294107Recruiting
Intestinal organoid study in digestive biopsies
This study collects small tissue samples (biopsies) during a routine endoscopy to create organoids—miniature versions of your intestine grown in a lab. The goal is to better understand digestive diseases and test potential treatments. You may be eligible if you're already scheduled for an endoscopy.
RennesAges 18–75 - NCT07670975Recruiting
Energy use in children with new IBD diagnosis
This study measures how many calories children with newly diagnosed inflammatory bowel disease (Crohn's or ulcerative colitis) burn at rest. It helps doctors understand and manage their energy needs.
Alessandria, PiedmontAges 6–17 - NCT07436910Enrolling by invitation
Quality of life in inflammatory bowel disease
This study asks people with inflammatory bowel disease to fill out questionnaires about their quality of life. It aims to learn how the condition affects daily living and well-being.
CairoAges 18 years+ - NCT07314151Recruiting
TCM tools for inflammatory bowel disease
This study compares people with Crohn’s disease or ulcerative colitis to healthy volunteers to see if traditional Chinese medicine tools can help identify unique features of these conditions, like changes in tongue coating. It aims to improve how we diagnose and understand inflammatory bowel disease.
Taichung, NorthAges 18 years+ - NCT03458195Recruiting
Crohn’s surgery follow-up for ileocecal resection patients
This study follows adults with Crohn’s disease who need surgery to remove the ileocecal area. It aims to better understand post-operative outcomes and what to expect after the operation.
LiègeAges 18–100 - NCT06710067Recruiting
Urine chemicals for diagnosing disease
This study looks at chemicals in urine to help find new ways to diagnose diseases. You give one urine sample and answer a few questions—no treatment or long-term follow-up needed.
Encinitas, CaliforniaAges 18 years+ - NCT07222189Enrolling by invitationPhase 2
Long-term safety of an experimental drug for Crohn's or colitis
This study looks at the long-term safety and side effects of an investigational drug called balinatunfib in people with Crohn's disease or ulcerative colitis. It is for patients who have already completed a full year of treatment in a previous related study.
Gorna OryahovitsaAges 19–77 - NCT06104631Recruiting
Testing a treatment for IBS-like symptoms in Crohn's remission
This study tests whether a new treatment can reduce IBS-like symptoms, such as belly pain and bloating, in people whose Crohn's disease is in remission. It aims to improve your quality of life without targeting active Crohn's inflammation.
LiègeAges 18–75 - NCT05733845Recruiting
Study of why some bowel inflammation treatments don’t work
This study looks at blood and/or tissue “molecular” (cell-level) reasons why treatments don’t fully work in adults with Crohn’s disease or ulcerative colitis. If you are starting a biologic or small-molecule medicine and still have moderate to severe symptoms, you may be able to contribute to research that helps improve future care.
Vandœuvre-lès-Nancy, CHRU de NancyAges 18 years+ - NCT07245394Recruiting
Switching to guselkumab for inflammatory bowel disease after ustekinumab
This trial tests whether switching from the drug ustekinumab to another drug called guselkumab can help people with active inflammatory bowel disease (IBD) who didn't get enough benefit from ustekinumab. It focuses on people with Crohn's disease or ulcerative colitis who still have signs of inflammation in their gut.
Calgary, AlbertaAges 18 years+ - NCT06810518Recruiting
Studying stool test for digestive disease diagnosis
This trial tests a new stool test to measure calprotectin levels, which could help doctors tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). If you have symptoms like stomach pain, diarrhea, or weight loss and are about to have a colonoscopy, you may be able to join.
Miami, FloridaAges 22 years+ - NCT07132333Recruiting
Personalized inflammation study for chronic conditions
This study uses advanced testing to understand inflammation in people with certain chronic inflammatory diseases, such as psoriasis, psoriatic arthritis, other types of arthritis, or inflammatory bowel disease. The goal is to tailor treatment to your specific needs.
TübingenAges 18 years+ - NCT07300553RecruitingPhase 2
Gut bacteria and energy metabolism in health and IBD
This study looks at how the bacteria living in your gut affect your body's energy use. It includes both healthy volunteers and people with inactive Crohn's disease or ulcerative colitis.
ParisAges 18–50 - NCT01140789Recruiting
Study comparing people with and without bowel inflammation
This study looks at people with inflammatory bowel disease (Crohn’s disease or ulcerative colitis) and compares them with people without it. Researchers want to understand differences that may help explain or better detect the disease.
Hong KongAges 18 years+ - NCT02636517Enrolling by invitationPhase 1
Fecal microbiome transplant for repeat C. difficile infection
This Phase 1 study tests whether transferring healthy gut bacteria (a fecal microbiome transplant) can help children with repeated or moderate-to-severe C. difficile infection. It focuses on changing gut bacteria to reduce ongoing infection and symptoms.
Philadelphia, PennsylvaniaAges 3–21 - NCT07102368Recruiting
Study of guselkumab for inflammatory bowel disease in Germany
This study tracks how well guselkumab (Tremfya) works in real-life for people with inflammatory bowel disease in Germany. If you are starting this treatment, researchers will watch your progress and ask you to fill out simple surveys about your symptoms.
BerlinAges 18 years+ - NCT06750731Recruiting
IV vs. shot vedolizumab for IBD with remote check-ins
This study compares two ways of taking the IBD medicine vedolizumab (injecting under the skin versus through an IV line). You'll use a smartphone app to report your symptoms, so you can participate from home and help doctors learn which option works better.
New Orleans, LouisianaAges 18 years+ - NCT06180382RecruitingPhase 4
Comparing vedolizumab to higher-dose adalimumab for Crohn's disease
This trial tests whether switching to vedolizumab works better than increasing your adalimumab dose if your Crohn's symptoms or inflammation are coming back despite treatment. It aims to find the best next step for people whose condition is no longer well-controlled.
Le Kremlin-Bicêtre, PARISAges 18 years+ - NCT07377188Recruiting
Pregnancy and Inflammatory Bowel Disease Study
This trial looks at how pregnancy affects and is affected by inflammatory bowel disease. It aims to learn more to help women with IBD who are or want to become pregnant.
AmiensAges 18–50 - NCT07632573RecruitingPhase 1
Safety Study of BDHK-2009 Tablets in Healthy Adults
This is an early-stage safety study testing a new experimental tablet called BDHK-2009 in healthy volunteers with no major illnesses. Researchers want to make sure the drug is safe and well-tolerated before testing it in people with medical conditions.
Hangzhou, ZhejiangAges 18–55
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Common questions
- Are there clinical trials for crohn’s disease?
- Yes. Clin2 currently lists 334 recruiting crohn’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.