Clinical trials
Crohn’s disease clinical trials
A type of inflammatory bowel disease causing inflammation of the digestive tract. We’re tracking 334 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06754891RecruitingPhase 1
A study of TQH3906 for moderate to severe inflammatory bowel disease
This trial tests a new medicine (TQH3906) for people with moderate to severe ulcerative colitis or Crohn's disease that hasn't improved with other treatments. The goal is to see if it can help control inflammation in the gut.
Bengbu, AnhuiAges 18–75 - NCT06587646Recruiting
Virtual reality for perianal Crohn's surgery
This trial is testing whether using virtual reality (VR) technology can help doctors better plan surgery for people with Crohn's disease around the bottom. It aims to improve how fistulas and abscesses are managed.
NottinghamAges 18–75 - NCT04617184Recruiting
Join an inflammatory bowel disease registry and sample bank
This study asks people with known or suspected inflammatory bowel disease to enroll in a registry and biorepository. It helps researchers better understand the condition using health information and stored biological samples.
Austin, TexasAges 18–100 - NCT06426316Recruiting
Immune cells and migraines study
This study looks at how certain immune cells and inflammatory chemicals relate to migraines. If you have migraines or an autoimmune condition (like lupus, rheumatoid arthritis, or Crohn's disease), you may be able to participate. The goal is to understand what causes migraines.
Clermont-Ferrand, AURAAges 18–50 - NCT06956703Recruiting
Nottingham IBD study testing new treatments
This study looks at people with active Crohn's disease or ulcerative colitis starting a new type of medication (anti-TNF, ustekinumab, upadacitinib, or vedolizumab), as well as people without IBD having a routine colonoscopy. It aims to collect information to better understand how these treatments work.
Nottingham, NottinghamshireAges 16 years+ - NCT04243525Recruiting
Inflammatory bowel disease patient research registry
This study is a research registry that collects information from adults receiving care for inflammatory bowel disease at UPMC. It may help researchers better understand bowel disease and improve future treatments.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04924270RecruitingPhase 2
Capsule stool transfer for newly diagnosed inflammatory bowel or joint disease
This Phase 2 study tests whether taking capsule stool (FMT) is safe and can help people who are newly diagnosed and haven’t started the usual medicines yet. Participants will also start the standard first-line treatment for their condition, and the study will compare safety and outcomes.
OdenseAges 18–75 - NCT07519850Recruiting
How Perianal Disease Affects Sexual Health and Quality of Life
This study explores how chronic perianal conditions—like anal fistulas or pilonidal disease—affect patients' sexual function and relationships. Researchers will ask you to complete surveys about your symptoms and sexual health to better understand this impact and help future patients.
Thessaloniki, ThessalonikiAges 18 years+ - NCT07224113Recruiting
Reducing ultra-processed foods in teens with IBD
This study looks at whether a simple educational program can help teens with IBD eat less ultra-processed foods (like fast food and sugary snacks). Participants will learn about healthier food choices during their regular infusion visits.
Hartford, ConnecticutAges 10–21 - NCT07686406Recruiting
IBD biomarker discovery study
This study collects blood, stool, tissue, and health information from people with inflammatory bowel disease (IBD), their relatives, and healthy volunteers to find patterns that may help diagnose or treat IBD better in the future.
Guangzhou, GuangdongAges 14 years+ - NCT07013578Recruiting
Mental health support trial for IBD patients
This trial tests a mental health program for people with inflammatory bowel disease (IBD) who have mild to moderate anxiety or depression. It aims to see if the program can improve their emotional well-being.
North York, OntarioAges 18–75 - NCT02103361Recruiting
Pregnancy registry for Stelara or Tremfya exposure
This study is a pregnancy exposure registry. It collects information to better understand pregnancy outcomes after exposure to Stelara or Tremfya (medicines used for autoimmune diseases).
La Jolla, CaliforniaAges Any age - NCT07621783Recruiting
Blood protein levels and bowel disease activity in IBD
This study measures a blood protein called LRG and compares it to how active your inflammatory bowel disease (IBD) is during a planned scope procedure. The goal is to see if this blood test could help doctors assess disease activity more easily in the future.
BonheidenAges 16 years+ - NCT06211400Recruiting
Vibration Exercise for Crohn's Disease Response
This study tests whether gentle whole-body vibration exercise can help people with mild to moderate Crohn's disease feel better. You will do short vibration sessions at a research center over several weeks.
Hatfield, UKAges 18–65 - NCT07524244Recruiting
Ketogenic and carnivore diets for IBD and rheumatoid arthritis
This study tests whether special diets (ketogenic or carnivore/meat-based) can help reduce inflammation and symptoms in people with inflammatory bowel disease or rheumatoid arthritis. You'll follow dietary guidelines for 3 weeks, then continue in the study while researchers track how you respond.
Charlottesville, VirginiaAges 18–64 - NCT07155148Recruiting
Argentine registry for Crohn's and colitis patients
This study collects information from people diagnosed with inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. By joining the registry, you help researchers learn more about these conditions and improve care.
Córdoba, Córdoba ProvinceAges Any age - NCT07237516Recruiting
Study of Zymfentra for people with Crohn's or colitis
This study follows adults with inflammatory bowel disease who are starting or switching to Zymfentra. Researchers will track your health over the next year to see how the medicine works in real life.
New Haven, ConnecticutAges 18 years+ - NCT04760964Recruiting
Testing blood markers in active Crohn’s and ulcerative colitis
This study looks for specific body signals (called mitochondrial “DAMPs”) that may reflect active inflammation in Crohn’s disease and ulcerative colitis. It also checks how these markers relate to what doctors see during colonoscopy or flexible scope exams, to help understand inflammation and potentially guide future care.
DundeeAges Any age - NCT05579392Recruiting
Bright light therapy for gut inflammation in Crohn’s or colitis
This trial studies whether daily bright light can improve gut barrier “leakiness” and reduce inflammation in adults with Crohn’s disease or ulcerative colitis. It compares bright light versus dim light in a crossover design, meaning you may receive both.
Chicago, IllinoisAges 18 years+ - NCT01731665Recruiting
Study of Crohn’s and ulcerative colitis in Seoul
This study looks at how inflammatory bowel disease (Crohn’s disease and ulcerative colitis) affects people in a specific area of Seoul. It mainly focuses on describing patterns and health needs rather than testing a new drug.
SeoulAges Any age - NCT05698745Recruiting
Study of the immune features soon after bowel disease starts
This study looks at immune system changes in people around the time inflammatory bowel disease (IBD) is first diagnosed, and compares different groups (new, very recent, or not found on scope). It may help researchers understand what the immune system looks like early in IBD and later in people who don’t show it on colonoscopy.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT07770425Recruiting
Measuring lesion size during gastrointestinal endoscopy
This study tests a new way to measure the size of abnormal areas found during a routine endoscopy procedure. It may help doctors make more accurate measurements, which could improve diagnosis and treatment planning.
Montreal, QuebecAges 18 years+ - NCT07686757Enrolling by invitationPhase 4
Study of mirikizumab for ulcerative colitis and Crohn's disease
This study tests a new medicine called mirikizumab for people with ulcerative colitis or Crohn's disease who have not responded well to other treatments. It aims to see if mirikizumab can help control symptoms and improve quality of life.
Sun City, ArizonaAges 21 years+ - NCT05230173Recruiting
Treat to endoscopic remission in inflammatory bowel disease
This study tests whether switching to a different treatment for inflammatory bowel disease (IBD) can achieve healing of the gut lining. It is for people whose symptoms are under control but who still have significant inflammation in their bowel.
Scottsdale, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for crohn’s disease?
- Yes. Clin2 currently lists 334 recruiting crohn’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.