Clinical trials
Crohn’s disease clinical trials
A type of inflammatory bowel disease causing inflammation of the digestive tract. We’re tracking 332 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07770425Recruiting
Measuring lesion size during gastrointestinal endoscopy
This study tests a new way to measure the size of abnormal areas found during a routine endoscopy procedure. It may help doctors make more accurate measurements, which could improve diagnosis and treatment planning.
Montreal, QuebecAges 18 years+ - NCT07724990Recruiting
Probiotic for gut health in mild-to-moderate colitis
This trial tests a specific probiotic (a type of beneficial bacteria) to see if it can help people with mild to moderate ulcerative colitis by improving the balance of gut microbes. It may be an option if you have not used many advanced treatments before.
Roma, RMAges 18–80 - NCT07710287Recruiting
Using a protein test to measure inflammation in IBD
This study looks at a protein called claudin 2 in tissue samples from people with inflammatory bowel disease (IBD). The goal is to see if it can help doctors tell whether inflammation is active or inactive. This could lead to a more accurate way to check disease activity.
San Donato Milanese, MiAges 18 years+ - NCT07686757Enrolling by invitationPhase 4
Study of mirikizumab for ulcerative colitis and Crohn's disease
This study tests a new medicine called mirikizumab for people with ulcerative colitis or Crohn's disease who have not responded well to other treatments. It aims to see if mirikizumab can help control symptoms and improve quality of life.
Sun City, ArizonaAges 21 years+ - NCT07654751RecruitingPhase 4
Study of Tremfya in breast milk of breastfeeding women
This study measures how much Tremfya (guselkumab) gets into breast milk for women who are already taking it for conditions like psoriasis or arthritis and choose to breastfeed. It helps understand if the drug passes to the baby.
Chapel Hill, North CarolinaAges 18 years+ - NCT03901235RecruitingPhase 1/Phase 2
Stem cell injections for Crohn’s lesions that won’t heal
This study tests injections of stem cells placed directly into Crohn’s affected tissue. It may help people whose Crohn’s disease lesions have not responded to standard medicines and biologic therapies.
Liège, LiègeAges 18 years+ - NCT07564609Enrolling by invitation
Infliximab injection therapy outcomes in inflammatory bowel disease
This study tracks how patients with Crohn's disease or ulcerative colitis respond to infliximab (a biologic medication) given as injections under the skin after an initial IV dose. Researchers want to understand which patients benefit most and for how long.
AmiensAges 18 years+ - NCT05636709Recruiting
Follow-up study for adults starting GMA for Crohn’s or colitis
This study follows adults with inflammatory bowel disease (Crohn’s disease or ulcerative colitis) after their doctor starts a treatment called GMA. It mainly looks at safety and how patients do in real-world care, and may help doctors understand how GMA works over time.
Albacete, AlbaceteAges 18 years+ - NCT07433946Recruiting
Liquid nutrition to prevent weight loss in IBD
This study tests whether adding a special liquid nutrition drink (partial enteral nutrition) to your regular diet can help prevent weight loss and muscle loss in people with Crohn's disease or ulcerative colitis who are at risk of malnutrition.
Rozzano, MilanoAges 18–65 - NCT07431983Recruiting
IBUS vs colonoscopy and enterography for UC and CD
This study compares a newer, possibly greener imaging method (IBUS) with standard colonoscopy and enterography for people with ulcerative colitis (UC) or Crohn's disease (CD). The goal is to see if IBUS is as helpful and produces less waste or carbon emissions.
Hyderabad, TelanganaAges 18–80 - NCT07347158Enrolling by invitation
Health education for ostomy patients
This study teaches people with an ostomy (a surgical opening for waste) about their health to improve their quality of life and reduce anxiety or depression. If you are an adult with a permanent or long-term ostomy and live in the Santiago or Barbanza area, you may be able to join.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT06862843Recruiting
Family eating habits and chronic inflammation study
This study looks at how eating habits and family health history relate to chronic inflammatory conditions like Crohn's disease, ulcerative colitis, and juvenile idiopathic arthritis. It aims to understand these links by studying families with a child or adult affected by these conditions, as well as healthy families.
Florence, ItalyAges Any age - NCT07319442Recruiting
German registry for inflammatory bowel disease
This is a long-term registry study that follows people with chronic inflammatory bowel diseases to better understand the conditions and improve care. By joining, you help researchers learn more about how these diseases affect patients over time.
HamburgAges 18 years+ - NCT06089590Recruiting
I-CARE 2 study on IBD, cancer and serious infections
This study follows adults with Crohn's disease, ulcerative colitis, or unclassified IBD to better understand the links between these conditions, cancer, and serious infections. It asks you to share personal details and complete online surveys over time.
AmiensAges 18–75 - NCT06516341Recruiting
Predicting bowel recurrence after surgery for chronic inflammation
This study follows patients with Crohn's disease or ulcerative colitis to see how their intestine heals after surgery. It looks for signs that can predict whether inflammation will return or complications will happen.
Milan, ItalyAges 18–69 - NCT07261826Recruiting
Long-term effects of fecal microbiota transplant
This study looks at how well fecal microbiota transplantation (FMT) works over time and checks its safety. If you have received at least one FMT for a qualifying condition, you may be able to participate.
Shanghai, Shanghai MunicipalityAges 3 years+ - NCT07169123Recruiting
Salt and inflammation in Crohn's disease study
This study looks at how salt affects inflammation in people with Crohn's disease. You will have blood and urine tests to measure how your body handles sodium and inflammation.
Hamilton, OntarioAges 18–70 - NCT07077681Recruiting
Switching from Stelara to a biosimilar for Crohn's disease
This study checks if it's acceptable for people with Crohn's disease to switch from the biologic medicine Stelara to a similar, lower-cost version called Uzpruvo. If you have been stable on Stelara for at least 6 months without needing steroids, you may be able to participate.
AmiensAges 18 years+ - NCT06997055Recruiting
Study of Steqeyma® biosimilar in Crohn's and psoriasis
This study follows people with Crohn's disease or plaque psoriasis who are switching from the reference Ustekinumab to a biosimilar (Steqeyma®). It aims to see how well the biosimilar works in real-world settings.
AmiensAges 18 years+ - NCT06997965RecruitingPhase 4
Mirikizumab for Crohn's with inflammatory strictures
This study tests a medication called mirikizumab to see if it can help people with Crohn's disease who have narrowing (strictures) in the small intestine caused by inflammation. The goal is to improve symptoms like belly pain after eating and to possibly reduce the narrowing without needing surgery.
Orlando, FloridaAges 18 years+ - NCT06468774Recruiting
Test for gut ischemia in chronic belly artery disease
This study tests a blood marker for chronic mesenteric ischemia (poor blood flow to the gut). If it works, it could help doctors diagnose the condition faster and more easily.
Oslo, OsloAges 18 years+ - NCT06698601Recruiting
Wild blueberries for colitis inflammation
This study tests whether eating wild blueberries can help reduce inflammation in people with Crohn's disease or ulcerative colitis. You would eat wild blueberries during your hospital stay and have a colonoscopy to see how your gut is doing.
Bamberg, BavariaAges 18 years+ - NCT06670638Recruiting
New test for crohn's disease in people with a permanent ileostomy
This study aims to develop a new way to measure inflammation and symptoms in people with Crohn's disease who have a permanent ileostomy. Participants will undergo a routine ileoscopy and answer questions to help create better tools for future clinical trials.
Rochester, MinnesotaAges 18 years+ - NCT06663332RecruitingPhase 3
Long-term study of guselkumab in children who previously took it
This study is a long-term follow-up for children who have already finished an earlier study of guselkumab, a medicine for skin conditions like psoriasis. It looks at whether staying on the medicine continues to be safe and helpful over time.
Atlanta, GeorgiaAges 3 years+
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Common questions
- Are there clinical trials for crohn’s disease?
- Yes. Clin2 currently lists 332 recruiting crohn’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.