Clinical trials · Houston, TX
Dementia clinical trials in Houston
We’re tracking 18 recruiting dementia studies with a site in or near Houston — including Phase 1/Phase 2, Phase 2, Phase 3 and Phase 4 studies, each written for real people, not researchers.
Recruiting studies near Houston
- NCT07602582RecruitingPhase 3
Donanemab Extension Study for Alzheimer's Disease
This is a follow-up study for people who already completed a previous donanemab trial (AACM). Donanemab is a medication designed to slow cognitive decline in early Alzheimer's disease by targeting amyloid buildup in the brain.
Houston, TexasAges 55 years+ - NCT07667478Recruiting
Brain stimulation study for early Alzheimer's memory loss
This study tests whether a non-invasive magnetic brain stimulation technique can help improve memory in people with early Alzheimer's disease. It may be an option if you have mild cognitive impairment or mild dementia due to Alzheimer's and have had a positive blood test for Alzheimer's markers.
Houston, TexasAges 55–90 - NCT06903078Recruiting
Shingles and Dementia Risk Study
This study looks at whether the virus that causes shingles (herpes zoster) might increase the risk of dementia. Participants with a fresh shingles rash will give blood samples and attend several follow-up visits over one year.
Houston, TexasAges 18 years+ - NCT07176286RecruitingPhase 2
PET scan study for diagnosing Lewy body dementia
This trial is testing a special PET scan that uses a radioactive tracer (18F-mFBG) to see how much it is taken up by the heart. The goal is to help tell Lewy body disease (Parkinson's or Lewy body dementia) apart from other brain disorders.
Houston, TexasAges 18 years+ - NCT06584357Recruiting
Digital and blood markers linked to brain scans in older adults
This study is looking for older adults (60–90) who are either cognitively normal, have mild cognitive impairment (MCI), or have mild-to-moderate Alzheimer's dementia. It aims to see how digital tests and blood-based markers relate to brain scans (amyloid and tau PET). You will need a study partner, undergo MRI and PET scans, and give blood samples.
Houston, TexasAges 60–90 - NCT06064890RecruitingPhase 1/Phase 2
Gene therapy trial for genetic frontotemporal dementia
This trial tests a new gene therapy called AVB-101 for people with a specific genetic cause of frontotemporal dementia (FTD). The therapy is given as a one-time injection into the brain to potentially slow or stop the disease.
Houston, TexasAges 30–75 - NCT06835283Recruiting
Brain stimulation for mood and behavior in Alzheimer's
This study tests a non-invasive brain stimulation treatment designed to help with difficult mood and behavior symptoms in people with Alzheimer's disease. If you are a veteran with mild to moderate Alzheimer's and have troubling symptoms like agitation, the treatment may help improve your quality of life.
Houston, TexasAges 65–85 - NCT07387614Enrolling by invitation
Web support for caregivers of Veterans with dementia
This study tests a web-based support program for people caring for a Veteran with dementia who has recently come home from a nursing facility. The program aims to help you manage caregiving challenges and connect with resources.
Houston, TexasAges 18 years+ - NCT05617014Enrolling by invitation
ADNI4 study for early Alzheimer’s with brain imaging tests
This study enrolls people with no memory impairment, mild memory problems, or mild Alzheimer’s dementia to test how brain scans and cognitive tests relate to Alzheimer’s disease. It may help by contributing to better early diagnosis and by letting you see whether you fit into the study’s imaging and blood-test pathway.
Houston, TexasAges 55–90 - NCT07029581RecruitingPhase 2
Testing ACP-204 for psychosis in Lewy body dementia
This trial tests a new drug called ACP-204 for people with dementia from Lewy body disease or Parkinson's who also have hallucinations or delusions. The goal is to see if the drug can safely reduce these symptoms without worsening thinking problems.
Houston, TexasAges 55–84 - NCT07651319RecruitingPhase 1/Phase 2
IL-2 and Semaglutide Treatment for Alzheimer's Disease
This study tests whether two drugs—IL-2 (an immune-boosting medication) and semaglutide (a diabetes drug that may help brain function)—can slow memory loss in people with Alzheimer's disease. Researchers believe these drugs together might help reduce brain inflammation and protect memory.
Houston, TexasAges 50–86 - NCT04262206RecruitingPhase 4
Testing how statins affect outcomes in adults 75 and older
This trial studies whether cholesterol-lowering medicine (a statin, specifically atorvastatin) improves health and benefits in people age 75 and older in everyday life. It may help doctors understand which older adults benefit most and how to use these medicines safely.
Houston, TexasAges 75 years+ - NCT04363684Recruiting
Study of frontotemporal dementia and related syndromes over time
This study follows people with frontotemporal dementia (FTLD) and related conditions, and collects health and (for some people) body fluid information, to understand how these illnesses change over time. It may help researchers track disease signs and find better ways to measure progression.
Houston, TexasAges 18 years+ - NCT06289569Recruiting
Home therapy for recovery after stroke-related dementia
This trial tests a home-based therapy program for people who have had a stroke that led to vascular dementia. The therapy focuses on improving arm and hand movement, and it is done remotely with a caregiver's help.
Houston, TexasAges 18–110 - NCT05397639RecruitingPhase 3
Masupirdine trial for agitation in Alzheimer’s dementia
This Phase 3 study tests masupirdine to see if it can reduce agitation in people with Alzheimer’s-type dementia. If you have Alzheimer’s dementia with confirmed agitation, joining could help researchers find better treatment options.
Houston, TexasAges 50–90 - NCT04916210Recruiting
Study how stroke type affects thinking and recovery
This study looks at what predicts memory and thinking problems after different types of stroke or brain bleeding, and how blood-vessel changes relate to recovery. You may be invited if you recently had a stroke/bleed and can complete a baseline check within 6 weeks.
Houston, TexasAges 18 years+ - NCT07095465Enrolling by invitationPhase 3
Long-term study of ACP-204 for psychosis in Lewy body dementia
This study tests a medication called ACP-204 for psychosis (hallucinations or delusions) in people with Lewy body dementia. It is a long-term extension open to patients who completed a previous ACP-204 study, to see if the drug continues to be helpful and safe.
Stafford, TexasAges 55–84 - NCT06245031Enrolling by invitation
Long-term follow-up of sensory stimulation for Alzheimer's
This is a follow-up study for people who already completed the 12-month Hope Study (CA-0011). It tests long-term safety and effects of a gentle sensory stimulation device (light and sound) for Alzheimer's disease. You will continue using the device at home with a study partner.
Stafford, TexasAges 50–92
Hear when a new Dementia trial opens near Houston, TX
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Dementia trials in other cities
Where these studies are running near Houston
Institutions with a site for the recruiting dementia studies listed above.
- Houston Methodist Hospital · 5 studies
- Baylor College of Medicine · 3 studies
- Horizon Clinical Research Center · 2 studies
- Michael E. DeBakey VA Medical Center · 2 studies
- R and H Clinical Research · 2 studies
- The University of Texas Health Science Center at Houston · 2 studies
- Center for Clinical Studies
- Clinical Trial Network
What taking part in a dementia study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting dementia studies in Texas.
Common questions
- Are there dementia clinical trials near Houston?
- Yes. We're currently tracking 18 recruiting dementia studies with a site near Houston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a dementia study near Houston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Houston to take part?
- Not necessarily. These studies have a site near Houston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New dementia studies open near Houston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.