Clinical trials
Dental Diseases clinical trials
Below are recruiting dental diseases clinical trials, each written for real people, not researchers. We’re tracking 50 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06182462Recruiting
Virtual reality for dental anxiety in children
This study tests whether wearing a virtual reality headset during dental treatment can help reduce fear and anxiety in children. If you feel nervous about dental visits, this may be a way to stay calm and comfortable.
Montreal, QuebecAges 6–17 - NCT07529444Recruiting
Testing ways to clean dental implants affected by infection
This study tests different methods to clean and treat dental implants that have developed an infection around them (peri-implantitis). The goal is to find the best way to remove harmful bacteria and save your implant.
ZagrebAges Any age - NCT07102121Enrolling by invitation
Comparing tooth sensitivity after cementing crowns with two dental materials
This study tests whether one type of dental cement causes less tooth sensitivity than another after placing a crown. The results could help your dentist choose the material that feels better for you.
Mingora, Khyber PakhtunkhwaAges 15–60 - NCT06196515RecruitingPhase 2/Phase 3
Study of a new nano-medication for infected tooth root canals
This trial tests whether a nano-scale calcium hydroxide paste works better than standard treatments for tooth infections. If you have a permanent molar with signs of infection around the root tip, this study may be an option.
CairoAges 21–49 - NCT06207253RecruitingPhase 2/Phase 3
Testing diclofenac gel for tooth root infections
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
CairoAges 18–50 - NCT04567030Recruiting
AI tool to help improve gum treatment outcomes
This trial tests whether an artificial intelligence (AI) system can help plan and improve results of gum (periodontal) treatment. You may be a good match if you have diagnosed periodontal disease and enough healthy teeth.
Kaohsiung CityAges 35–65 - NCT06286501Recruiting
Preventive treatment for teens at risk of oral diseases
This trial tests a new preventive treatment for teenagers at risk of tooth decay and gum disease. It uses a special mouthpiece device (Lumoral) to clean teeth better and see if it can prevent oral health problems.
Tampere, PirkanmaaAges 14–16 - NCT06844448Recruiting
Factors affecting success of vital pulp therapy
This trial looks at how different risk factors affect the success of vital pulp therapy, a treatment that tries to keep the nerve of your tooth healthy after it's been opened during a dental procedure. If you have a tooth that still responds to cold and can be restored, you may be able to join.
BudapestAges 18 years+ - NCT06173167Recruiting
Same-day zirconia crowns for back teeth
This study tests a new type of same-day zirconia crown made in the dentist's office. It compares two different zirconia materials for strength and durability, and aims to see which one works best for back teeth.
Ann Arbor, MichiganAges 18 years+ - NCT07511673Recruiting
Dental screening before heart valve surgery
This trial tests whether a dental checkup before heart valve surgery can improve recovery and prevent complications. If you are scheduled for a heart valve procedure, you may be able to join.
GothenburgAges 18 years+ - NCT06948162Recruiting
Testing dental MRI for routine dental care
This study explores whether a dental-dedicated MRI can be used for routine dental imaging. It may help improve dental care by providing detailed images without radiation.
Minneapolis, MinnesotaAges 18 years+ - NCT06506734Recruiting
Dental color changes and quality of life in early jaundice
This study looks at how early and long-lasting jaundice (high bilirubin levels) affects tooth color and quality of life in children with certain liver conditions. It aims to understand these effects to improve care.
BordeauxAges 12–18 - NCT07031856Recruiting
3D printed vs. CAD-CAM dental restorations comparison
This trial compares two modern ways to make partial dental restorations (like crowns or bridges): one using a 3D printer and the other using a computer-aided design and manufacturing (CAD-CAM) system. It aims to see which method works better for people who need a couple of teeth fixed.
Adana, SarıçamAges 18–65 - NCT06836882Recruiting
Testing cavity disinfectants for deep tooth decay pain
This study tests two cavity disinfectants to see which one better reduces pain and improves healing after removing deep decay from back teeth. It is for adults with deep cavities in their lower molars that are still alive (not needing a root canal).
HaryānaAges 18 years+ - NCT07732647Enrolling by invitation
Immediate tooth replacement with a temporary implant crown
This trial tests placing a temporary crown on a dental implant right after removing a front tooth. It may be an option if you need a front tooth replaced and have good overall health and oral hygiene.
Ann Arbor, MichiganAges 18 years+ - NCT07688421Enrolling by invitation
Short 3D-printed implants for back jaw teeth: 3-year study
This trial tests shorter implants made with 3D-printing for replacing missing teeth in the back of the mouth. Researchers will check how well they work over 3 years using X-rays.
Guarulhos, São PauloAges 18 years+ - NCT03384537RecruitingEarly Phase 1
Tropolone mouthwash test in healthy adults
This early trial compares a mouthwash that contains tropolone versus a mouthwash without tropolone to see how well each works against germs in the mouth. You may be asked to pause your usual mouth-cleaning routine for a few days beforehand.
CairoAges 18–45 - NCT05688982Recruiting
Check oral health needs and local care resources in the ER
This study asks people in the emergency department (and their parents/guardians) about oral health needs and what local resources they can access. It aims to map gaps in dental and oral health support so future care can be better targeted.
Boston, MassachusettsAges 1 year+ - NCT06252935Recruiting
Collagen membrane for gum and bone repair
This trial tests a new collagen membrane (FormaAid®) for repairing gum and bone damage from gum disease. It may help people with deep gum pockets and bone loss who are not smokers and have well-controlled health conditions.
Taipei, TaiwanAges 18–70 - NCT06787261Recruiting
Study of oral microbes linked to cavities
This study looks for tiny organisms called archaea in the mouth and how they might be related to cavities. It may help us learn more about what causes tooth decay.
MarseilleAges 18 years+ - NCT06808373Recruiting
Hypnosis for gum disease treatment
This study tests whether hypnosis can help with gum disease treatment. It is for adults who have chronic gum disease but are otherwise healthy.
AfyonkarahisarAges 20–65 - NCT06854744Recruiting
Olive oil and zinc oxide for baby tooth root canals
This study tests a mixture of olive oil and zinc oxide to treat infected baby molars. It aims to see if this natural treatment works as well as standard medicine for stopping infection and saving the tooth.
Tanta, Gharbia GovernorateAges 4–7 - NCT07239505Recruiting
Pre-operative medication for tooth pain relief study
This trial tests a medication called Trinase, given before a root canal, to see if it reduces pain after the procedure compared to a placebo. It may help if you have a painful tooth that needs treatment.
Al Fayyum, Faiyum GovernorateAges 18–50 - NCT07452614Recruiting
Predicting pulp treatment success with metabolic markers
This trial tests if a metabolic biomarker can predict how well a vital pulp treatment works for tooth pain caused by deep cavities. It aims to help patients keep their natural teeth instead of needing root canals.
BaghdadAges 16–50
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Common questions
- Are there clinical trials for dental diseases?
- Yes. Clin2 currently lists 50 recruiting dental diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.