Clinical trials
Dental clinical trials
Below are recruiting dental clinical trials, each written for real people, not researchers. We’re tracking 459 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06892184Recruiting
How the dentist talks during numbing injections
This study tests whether the way your dentist communicates with you during a numbing shot (para-apical anesthesia) affects your pain and comfort. It may help find the best way to talk to patients during dental procedures.
Clermont-FerrandAges 18 years+ - NCT06898918Enrolling by invitation
Mothers' feeding habits and kids' eating and tooth health
This study looks at how mothers control their child's eating, how the child eats, and whether it relates to early childhood cavities. It may help families understand what affects their preschooler's dental health.
CairoAges 3–5 - NCT06890988Recruiting
Dental team study to help end HIV epidemic
This trial tests if training dental teams (dentists, hygienists, assistants, navigators) can help end the HIV epidemic by offering HIV testing and prevention in dental visits. You may be able to join if you work in a dental practice that is part of this study.
New York, New YorkAges 18 years+ - NCT06876064Recruiting
Tracking people at risk for rheumatoid arthritis
This study follows different groups of people—from those at high risk of developing rheumatoid arthritis to those recently diagnosed—to learn more about the disease. By joining, you help researchers understand who gets RA and why, which may lead to earlier detection and better care.
Montpellier, HéraultAges 18–80 - NCT06824493Recruiting
How Braces Affect Mouth Bacteria and Saliva
This study looks at how braces (orthodontic treatment) change the bacteria and proteins in your mouth. Healthy volunteers who have never had dental work or cavities are needed to provide saliva samples before and during treatment.
Xi'an, ShaanxiAges 6–18 - NCT06803576Enrolling by invitation
Long-term study of dental implants after 10 to 22 years
This study looks at how well dental implants work and how healthy the mouth stays more than 10 years after implant placement. The goal is to learn about implant success and any gum or bone changes over time.
ThessalonikiAges 18 years+ - NCT06797778Enrolling by invitation
Oral health program for schoolchildren
This trial is a program to teach kids in Polígono Sur schools how to take care of their teeth and gums. It's a simple, no-risk way to learn about oral health.
Seville, SevillaAges Any age - NCT06791694Enrolling by invitation
Comparing tooth color measurement methods for dental students
This trial tests different ways to measure tooth color in healthy young adults. It aims to see which method works best for dental students to learn.
Altındağ, AnkaraAges 18–40 - NCT06787261Recruiting
Study of oral microbes linked to cavities
This study looks for tiny organisms called archaea in the mouth and how they might be related to cavities. It may help us learn more about what causes tooth decay.
MarseilleAges 18 years+ - NCT06762210Recruiting
Quit smoking with AI and dental health checks
This trial tests whether a smartphone app that uses artificial intelligence (AI) can help you quit smoking by looking at how it affects your dental health. If you smoke at least 5 cigarettes a day and want to quit, you may be able to join.
Fayoum, Alexandria GovernorateAges 21–65 - NCT06757075RecruitingPhase 4
Managing pain after children's dental surgery
This study tests different ways to manage pain in young children after dental surgery done under general anesthesia. It aims to find the best method to keep children comfortable and reduce discomfort.
Brighton, MassachusettsAges 4–6 - NCT06736964Enrolling by invitation
Testing new fillings for gum-line cavities in high-risk adults
This study tests how well two newer, tooth-friendly filling materials work for cavities at the gum line in people who are prone to tooth decay. If you need a couple of these fillings, this trial could help restore your teeth and protect them from future cavities.
CairoAges 25–45 - NCT06725134Recruiting
Do therapy dogs help kids feel calmer during dental shots?
This study tests if having a trained therapy dog in the room reduces a child's anxiety and improves their behavior when getting numbing medicine for dental work. It could help children who are nervous about dental procedures feel more at ease.
Ann Arbor, MichiganAges 4–12 - NCT06727110Recruiting
New liquid treatment for tooth cavities
This study tests a new method to treat cavities that reach the middle layer of a tooth. It may help repair the tooth with a liquid that hardens into a filling. If you have a back tooth with a cavity that hasn't been filled yet, you might be eligible to join.
San Francisco, CaliforniaAges 18–64 - NCT06152081Recruiting
Detecting cavities with two new devices
This study tests two different devices for finding cavities in adults at high risk for tooth decay, comparing how well they work against each other and standard methods.
Boston, MassachusettsAges 21 years+ - NCT06713330Recruiting
Stainless steel vs. resin crowns for baby molars
This study compares two types of dental crowns (stainless steel vs. resin) for baby molars to see which works better. If your child needs full mouth dental work under general anesthesia, they may be able to join.
Cincinnati, OhioAges 2–5 - NCT06714929Recruiting
School water study for students in grades K-5
This study looks at how a new water program in schools might affect student health and hydration. It includes watching what kids drink at lunch, checking teeth and body weight for older students, and asking 4th and 5th graders and staff about their drinks.
Henrico, VirginiaAges 4 years+ - NCT06576063Recruiting
Light therapy for better oral hygiene in older adults
This study tests a special light therapy (called antibacterial photodynamic therapy) used with a device called Lumoral to improve oral hygiene in older adults. It may help reduce bacteria and plaque in people who can brush their teeth and follow the study routine.
Loviisa, UusimaaAges 65 years+ - NCT05663385Recruiting
Testing a gum graft seal during follow-up care
This follow-up study checks whether using Mucograft Seal during aftercare can improve healing for people who took part in an earlier trial. It may help by supporting healthier gum and mouth recovery over time.
RotterdamAges 18 years+ - NCT06685640Recruiting
Comparing metal and ceramic crowns for back baby teeth
This trial tests whether stainless steel or zirconia crowns work better for fixing cavities in children's back baby teeth after nerve treatment. It can help parents choose the best option for their child.
Aydin, AydınAges 4–5 - NCT06647381Enrolling by invitation
Long-term outcomes of implants with sinus lifts
This study looks at how well dental implants hold up many years after a sinus lift procedure. If you had a sinus lift and implant around 1997–2001 at the University of Bern, you may be asked to come in for an exam to check your implant health.
BernAges 18–100 - NCT06619574Recruiting
Testing the dental compass for jaw joint positioning
This study tests a new tool called a Dental Compass that helps dentists place your jaw joint back in the right position more accurately and quickly. It may help relieve TMJ pain and improve jaw function.
Gainesville, TexasAges 18–90 - NCT06588725Enrolling by invitation
Parent program to prevent cavities in young children
This study tests simple ways to help parents improve their child's dental health and prevent cavities. It focuses on changing behaviors to keep your child's teeth healthy.
Nashville, TennesseeAges 9 months–3 years - NCT06571812Recruiting
Study of the TSX dental implant system (Xpresso)
This trial tests a new dental implant system (called TSX Xpresso) for replacing a single missing tooth, either right after pulling the tooth or after the gum has healed. It may be a good option if you need a dental implant and want to see how this system works.
Columbus, OhioAges 18 years+
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Common questions
- Are there clinical trials for dental?
- Yes. Clin2 currently lists 459 recruiting dental studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.