Clinical trials
Dental clinical trials
Below are recruiting dental clinical trials, each written for real people, not researchers. We’re tracking 459 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06569329Recruiting
Extra cleaning for infected root canals
This study tests if extra cleaning steps after a standard root canal can remove more bacteria from an infected tooth. It is for adults with a dead nerve and an infection at the root tip in a single-rooted premolar that has never been treated before.
Iowa City, IowaAges 18–95 - NCT06555029Recruiting
Oral health help for older adults on Medicaid
This trial is testing an oral health program offered during routine primary care visits for older adults (55+) on Medicaid. It aims to see if adding dental care support to regular check-ups can improve health.
Cleveland, OhioAges 55 years+ - NCT06507709Enrolling by invitation
Sinus lift study using a special bone graft putty
This study tests a new type of bone graft putty for people who need a sinus lift before getting dental implants. It may be an option if you have some existing bone and are generally healthy or have well-controlled diabetes.
San Antonio, TexasAges 18–85 - NCT06468111Recruiting
Can therapy dogs help kids during blood draws or dental work?
This study tests if having a gentle therapy dog nearby can help children ages 3 to 12 feel calmer and more comfortable during a blood draw or dental procedure. If your child likes dogs and needs one of these procedures, this might be a good fit.
LleidaAges 3–12 - NCT06275789Recruiting
Bone graft mix for preserving jawbone after tooth extraction
This study tests a mix of two bone graft materials (one from donated human bone and one from cow bone) to see if it helps preserve the jawbone after a tooth is pulled, so there is enough bone for a dental implant later. It may be a good option if you are generally healthy and need a molar or premolar removed.
Fort Lauderdale, FloridaAges 18 years+ - NCT06430268Enrolling by invitation
Cleaning methods for infected dental implants
This study is testing different ways to clean a dental implant that is failing due to severe infection (peri-implantitis). If you need to have an implant removed because of advanced bone loss, the researchers will compare cleaning methods during the removal procedure.
Pittsburgh, PennsylvaniaAges 18–80 - NCT06433297Recruiting
Direct vs. indirect pulp capping for deep cavities in lower molars
This study compares two ways to treat deep cavities in lower back teeth when the nerve is exposed. The goal is to see which method better protects the nerve and avoids the need for a root canal.
Rohtak, HaryanaAges 18 years+ - NCT06406751Enrolling by invitation
MI Paste and mouth bacteria in older denture wearers
This study tests whether a special paste (MI Paste) used for several months can change the natural bacteria in the mouth of older adults who wear dentures. It may help keep your mouth healthier.
Iowa City, IowaAges 65–105 - NCT06388395Enrolling by invitation
Comparison of PEEK and Conventional Dental Prostheses
This study compares two types of full-arch dental prostheses (PEEK and conventional) placed on four implants in the lower jaw, to see which works better. It may be an option if you need all lower teeth replaced and have healthy jawbone.
Sharjah cityAges 18 years+ - NCT06342258RecruitingPhase 1
Sealant order: does it matter for children's teeth?
This study tests whether the order in which a dentist applies sealant to a child's molars affects how well the sealant works. It is for healthy children ages 5–14 who have permanent molars on both sides of their mouth and can cooperate during a dental visit.
Los Angeles, CaliforniaAges 5–14 - NCT06330207Recruiting
Emergency provider training for dental care
This trial teaches emergency department doctors and advanced providers how to better manage dental emergencies. It aims to improve care for patients with non-traumatic dental problems.
Gainesville, FloridaAges 18 years+ - NCT06315348Recruiting
Gum shaping during braces with a vibration tool
This trial tests a new, less invasive surgical technique (using a special tool that vibrates, not a scalpel) to help reshape the gums while straightening teeth with braces. It is for people who need braces for mild to moderate crowding and have healthy gums.
MadridAges 16–70 - NCT06275191Enrolling by invitation
Testing non-opioid pain relief after tooth extraction
This trial tests whether alternative pain treatments can replace opioid painkillers after wisdom tooth or other tooth removal in teens and young adults. It aims to find safer ways to manage dental pain without relying on opioids.
Lexington, KentuckyAges 12–25 - NCT06276335Recruiting
Timing of dental implant placement and early healing
This trial compares placing a dental implant right after a tooth is pulled versus waiting for the socket to heal first. It aims to see which timing leads to better healing at the molecular level.
LondonAges 25 years+ - NCT06182293Recruiting
Mouth bacteria in early systemic sclerosis
This study looks at the bacteria in the mouth (periodontal microbiota) of people with early systemic sclerosis compared to those without the condition. It may help understand if there is a link between oral health and systemic sclerosis.
StrasbourgAges 18 years+ - NCT06138405Recruiting
Dental training for kids and dentists
This study tests a program to help dental providers and parents interact better with children during dental visits. The goal is to make the experience less stressful and more effective for everyone.
Fayetteville, ArkansasAges 18–99 - NCT06135714RecruitingPhase 3
Targeting limited breast cancer spread with focused therapy
This trial tests whether treating just the few spots where breast cancer has spread (called oligometastases) with radiation or surgery can help control the disease. It is for people whose cancer has spread to 3 or fewer places, each small in size, and who are healthy enough for local treatments.
Bunkyō-Ku, TokyoAges 18 years+ - NCT06149585Recruiting
Bacteria changes in gum disease patients getting all dental implants
This study looks at how bacteria in your mouth change when all your teeth are removed and replaced with dental implants. If you have severe gum disease and need all your teeth extracted, joining this trial could help researchers understand your healing process.
Cleveland, OhioAges 21 years+ - NCT05852145RecruitingPhase 1/Phase 2
Testing sweet drinks effect on children’s mouth health
This early-stage study looks at how drinking soft drinks with and without sweeteners affects children’s mouths and teeth. It may help researchers understand which types of sweet drinks contribute to more tooth damage.
Mexico City, CuahutemocAges 12–18 - NCT06110611Enrolling by invitation
Zirconia crowns on titanium abutments: 5-year study
This study checks how well a type of ceramic crown (zirconia) attached to a titanium base works for replacing a single missing back tooth. It looks at results 5 years after treatment.
GroningenAges 18 years+ - NCT06099717Recruiting
Testing a two-tooth dental bridge on one implant
This study tests if a special bridge supported by a single implant can replace three missing back teeth. It may help people who have a large enough jawbone and good overall health.
Goiânia, GoiásAges 18 years+ - NCT06086873Recruiting
Comparing two dental implant surfaces for healing
This study compares two types of dental implant surfaces to see which helps the implant bond better with the jawbone after a tooth is pulled. It may help you if you need a single front tooth or first premolar replaced.
LondonAges 18 years+ - NCT06075017Recruiting
Zirconia vs. titanium implants and biofilm buildup
This trial compares how much biofilm (a sticky layer of bacteria) builds up on two types of dental implants – one made of zirconia (a white ceramic) and one made of titanium (a metal). It's for people getting a single implant to replace a missing tooth.
Madrid, MadridAges 18–99 - NCT06012071Recruiting
Zirconia implants for a missing upper premolar
This trial tests two types of zirconia (ceramic) dental implants for replacing a single missing upper premolar. It aims to see which implant platform works best for long-term stability.
LjubljanaAges 25 years+
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Common questions
- Are there clinical trials for dental?
- Yes. Clin2 currently lists 459 recruiting dental studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.