Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,507 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07220486Recruiting
Depression support program for nursing home residents and their helpers
This study tests a program for nursing facility residents who have symptoms of depression and their care partners. It aims to provide emotional and practical support during a short stay.
Boston, MassachusettsAges 18 years+ - NCT07188467Recruiting
Stress and well-being support for international students
This study tests a self-help program called 'SH+' designed to reduce stress and improve well-being in international students at The New School. If you are an international student feeling at least mildly distressed, this program may help you develop coping skills.
Brooklyn, New YorkAges 18 years+ - NCT05548244Recruiting
Testing behavioral activation for teens with depression
This study looks at how a therapy approach called behavioral activation may affect depression in teens. It also uses brief daily check-ins on a phone to understand what changes during treatment.
Atlanta, GeorgiaAges 15–17 - NCT06557642Recruiting
Laughing Gas and Emotional Thinking Study
This study tests how nitrous oxide (laughing gas) affects your emotions and thinking. It's looking for healthy volunteers ages 18 to 40 to see how the gas might change emotional processing.
OxfordAges 18–40 - NCT06817993Recruiting
How social media affects the teen brain
This study looks at how social media affects the brains of teens with depression. You would complete smartphone surveys and have one brain scan (MRI) to help researchers understand these connections.
Pittsburgh, PennsylvaniaAges 13–17 - NCT07305415Recruiting
Emotion support program for dementia caregivers
This trial tests a program designed to help informal caregivers of people with dementia manage their expressed emotions. If you care for a loved one with dementia and feel emotionally stressed, this program may help you regulate your feelings and improve your caregiving experience.
Hong KongAges 18–100 - NCT06490315Enrolling by invitation
Studying OkeyMind for social anxiety in young people
This trial tests if a smartphone program called OkeyMind helps reduce social anxiety in young people aged 15-24. It also looks at whether the program is worth the cost.
Hong Kong, Hong KongAges 15–24 - NCT01809080Enrolling by invitation
Intern and medical student health check study
This study looks at the health of new interns and some final-year medical students in several training programs. It may help improve care and support for people early in their medical careers.
Ann Arbor, MichiganAges Any age - NCT06716996Recruiting
Brain stimulation for mood problems after COVID-19
This study tests if repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation technique, can help people aged 18 to 65 who have ongoing depression or low mood for more than 12 weeks after a confirmed COVID-19 infection. The treatment uses magnetic pulses to gently stimulate parts of the brain involved in mood regulation.
Zurich, Canton of ZurichAges 18–65 - NCT06882798Recruiting
New support program for Latinx teens with suicidal thoughts
This study tests a new support program for Latinx teens who have had serious thoughts about suicide or a suicide crisis in the past year. It involves working with both you and your family to find ways to help you feel safer and more supported.
Providence, Rhode IslandAges 12–18 - NCT07590999Recruiting
Probiotics and Menopause Symptoms: A Research Study
This study tests whether taking a probiotic supplement helps with hot flushes, mood changes, and other symptoms of perimenopause (the years around menopause). Researchers believe gut health may play a role in these symptoms.
Oxford, EnglandAges 45–60 - NCT06009523Recruiting
Testing brain stimulation for suicidal thoughts
This study tests a non-invasive brain stimulation technique called tDCS, which uses mild electrical currents to reduce suicidal thoughts in people with depression. If you have moderate to severe depression and still have suicidal ideation despite treatment, this might be an option.
Faye-l'AbbesseAges 18 years+ - NCT05862636Recruiting
Testing who benefits most from mindfulness meditation
This study looks at people who take part in a mindfulness program at specific study locations and examines who does best. You might be eligible if you are already joining the mindfulness intervention and can complete study tasks in the required language.
AntwerpAges 18 years+ - NCT06835985Enrolling by invitation
Social media help for teens bullied online
This study tests a social media program to help teens who have been bullied online and feel depressed. It aims to see if the program can reduce their sadness and help them cope better.
Philadelphia, PennsylvaniaAges 12–18 - NCT06639477Recruiting
Mood and sleep improvement study for older adults
This study tests whether adding a sleep treatment to regular depression medication can improve both mood and sleep in adults aged 55 and older. It may help if you have ongoing depression, sleep problems, and are already taking antidepressant medication.
Los Angeles, CaliforniaAges 55 years+ - NCT07436117Recruiting
AI avatar therapy for depression at work
This study tests whether talking with an AI-powered virtual avatar can help reduce depression and keep you at work. It is designed for people currently experiencing depressive symptoms who are not already in therapy.
LondonAges 18 years+ - NCT06631781Recruiting
Study on thinking skills in older adults with depressive symptoms
This study tests whether a tablet-based program can help older adults with depressive symptoms improve their thinking and control skills. If you have low mood and are comfortable with a tablet, you may be able to join.
JerusalemAges 65 years+ - NCT01415310Recruiting
Registering geriatric mental health patients and families
This study sets up a quality registry to better understand and improve care in geriatric psychiatry units. It includes patients who receive care there and their relatives, as long as they agree to take part by signing consent.
OsloAges 65 years+ - NCT06604481Recruiting
Online coaching for family caregivers
This study tests a 6-week online coaching program to help family caregivers reduce stress and build resilience. You'll learn practical strategies you can use at home.
Hong KongAges 18 years+ - NCT06494384Recruiting
Problem-solving treatment in community health centers
This trial tests if training therapists in a specific counseling method (problem-solving treatment) helps patients with depression. It's for adults who have depression and are seen at certain community health centers.
Portland, OregonAges 18 years+ - NCT06424314Recruiting
Trial on why some patients fail to come off a ventilator
This trial is studying why some people have trouble coming off a breathing machine (ventilator). It's for patients who've been on a ventilator for at least 2 days and don't have certain other conditions.
Guangzhou, GuangdongAges 18 years+ - NCT06072677Recruiting
Mood and testosterone in young teens
This study looks at how mood changes during puberty in young people aged 11 to 14. It tests whether using a mindfulness app (Healthy Minds) can help teens who have been through stress or feel down.
Chapel Hill, North CarolinaAges 11–14 - NCT06139861Recruiting
Better Sleep Study
This study tests a program to help you sleep better. It is for people who are generally healthy and do not have serious medical or mental health conditions.
Los Angeles, CaliforniaAges 12–18 - NCT06130371Recruiting
Stress, Inflammation & Brain in Depression vs. Severe PMS
This study looks at how stress and inflammation affect the brain in women with major depression compared to women with severe PMS (PMDD). It could help find better ways to understand and treat these mood disorders.
Tübingen, Baden-WurttembergAges 18–40
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,507 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.