Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,419 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06273137Recruiting
Positive affect treatment for teens with early adversity
This trial tests a treatment designed to improve positive emotions in adolescents who have experienced stressful early life events. It may help your teen build resilience and emotional wellbeing.
Irvine, CaliforniaAges 12–16 - NCT06261463Recruiting
Peer-led support group for refugee families in Chicago
This study is testing a support program led by trained peers to help refugee families strengthen family bonds and cope with challenges. It is designed for Arabic-speaking families who have recently settled in Chicago.
Chicago, IllinoisAges 12–55 - NCT06262178Recruiting
Parenting support for mothers in military families
This study tests a parenting program designed to help mothers in military families cope with past trauma and improve their relationship with their child. The program aims to reduce PTSD and depression symptoms while increasing parenting confidence.
El Paso, TexasAges 18 years+ - NCT06183359Recruiting
Self-Identification Program for Depression
This study tests a self-identification program for people aged 18 to 70 who are currently in a major depressive episode. It aims to explore whether a simple self-monitoring tool can help you better manage your depression.
MontpellierAges 18–70 - NCT06236919Recruiting
Virtual reality for emotional regulation in kids and teens
This study tests a virtual reality program designed to help children and teens learn to manage their emotions. It's offered in schools and aims to improve emotional regulation skills.
BarcelonaAges 10–16 - NCT06248203Recruiting
Teacher-led mental health support for teens in Darjeeling
This trial tests a program in which teachers get extra training to support students with emotional or behavioral challenges in low-cost private schools in Darjeeling. It aims to see if teachers can make a positive difference for these teens.
Darjeeling, West BengalAges 13 years+ - NCT06246214Recruiting
Biological rhythms for perinatal mental health
This study looks at whether understanding your body's daily rhythms (like sleep and activity) can help treat depression after childbirth. If you are 4-6 weeks postpartum and have been diagnosed with postnatal depression, this could be an option for you.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT06212219Recruiting
EEG brain training to help arm recovery after stroke
This study tests whether a brain-training technique called neurofeedback can improve arm movement in people who recently had a stroke. It uses an EEG cap to measure your brain activity while you do arm exercises, helping you relearn how to move your affected arm.
ToulouseAges 18–99 - NCT06226155Recruiting
HIV prevention support for pregnant women in Zimbabwe
This study in Zimbabwe tests a program to help pregnant women start and stay on PrEP (medication that prevents HIV). It aims to make PrEP easier to use during pregnancy for women who are at risk of HIV.
HarareAges 15–55 - NCT06221020Recruiting
Enhanced recovery after pituitary tumor surgery
This study tests a standard care plan to help patients recover faster after surgery to remove a pituitary tumor. It may reduce hospital stay and improve recovery.
Kaohsiung CityAges 20–75 - NCT06215313Enrolling by invitation
Comparing two therapies for trauma memories
This study compares two types of therapy—EMDR and imagery rescripting—to help people who have upsetting memories or nightmares from past events. It's for people with depression or PTSD, and you'll need to come to therapy twice a week.
Eindhoven, North BrabantAges 18–70 - NCT06200155RecruitingPhase 2
Psilocybin therapy for advanced cancer patients with anxiety or depression
This trial tests whether a drug called psilocybin, given with therapy, can help people with advanced cancer who are feeling anxious or depressed. You must have a stable cancer and be willing to travel to Houston for treatment.
Houston, TexasAges 25 years+ - NCT06162741Recruiting
Brief mindfulness training for Veterans in primary care
This study tests whether brief mindfulness training offered in VA primary care can help Veterans with symptoms of PTSD, depression, or anxiety. It aims to see if this approach works well in everyday clinic settings.
Phoenix, ArizonaAges 18 years+ - NCT06178328Recruiting
Online mental health program for Canadian adults
This study is testing a short online mental health program for adults in Canada who are seeking help. It aims to see if the program helps people feel better.
Regina, SaskatchewanAges 18 years+ - NCT06130371Recruiting
Stress, Inflammation & Brain in Depression vs. Severe PMS
This study looks at how stress and inflammation affect the brain in women with major depression compared to women with severe PMS (PMDD). It could help find better ways to understand and treat these mood disorders.
Tübingen, Baden-WurttembergAges 18–40 - NCT06139861Recruiting
Better Sleep Study
This study tests a program to help you sleep better. It is for people who are generally healthy and do not have serious medical or mental health conditions.
Los Angeles, CaliforniaAges 12–18 - NCT06142955Recruiting
TMS therapy for depression in autism spectrum disorder
This study tests whether transcranial magnetic stimulation (TMS), a noninvasive brain stimulation technique, can help treat depression in people with autism spectrum disorder. It may help if you are between 18 and 40, have autism and depression, and are not taking medications that could interfere.
New Haven, ConnecticutAges 18–40 - NCT06085937RecruitingPhase 1
Ketamine for suicidal patients in the ER
This trial tests if a single dose of ketamine can quickly reduce suicidal thoughts in people who come to the emergency department. If you are having active suicidal thoughts and need inpatient care, you may be able to join.
Kansas City, KansasAges 18–65 - NCT06087159Recruiting
Mental health toolkit for teachers and caregivers in Uganda
This trial tests if a personalized mobile health toolkit can help teachers and caregivers in Uganda manage stress and support mental health. If you are a teacher or a parent in the study schools, this program may provide tools to improve your wellbeing.
KampalaAges 18 years+ - NCT06093906Recruiting
Positive processes and transition to health (PATH) study
This study tests a new therapy that may help people recover after a stressful life event. Over about 6 weeks, you'll work with a coach to retrain your brain's patterns and feel more in control again, as well as reconnect with positive activities.
Newark, DelawareAges 18–65 - NCT06085313Recruiting
Web-based program for cancer pain in Asian women
This trial tests a web-based program to help women of Chinese, Korean, or Japanese heritage manage breast cancer pain and depressive symptoms. If you've had breast cancer, have had pain in the past week, and feel some depression, this program could help you cope better.
Austin, TexasAges 18 years+ - NCT06093282Enrolling by invitation
Community activity program for health and mood
This study tests if a community-based activity program can improve both mood and heart health in people who have limited access to healthcare or live in less-resourced neighborhoods. You may be able to join if you have symptoms of depression and are not very physically active or have a higher body weight.
Chicago, IllinoisAges 18 years+ - NCT05418894Recruiting
Study brain signals and improve treatment-resistant depression
This trial studies how brain activity relates to feelings and depression, using brain electrodes to measure signals. It’s meant for people with long-lasting, treatment-resistant major depression who may need stimulation while continuing psychiatric care.
Houston, TexasAges 22–70 - NCT05734313Recruiting
Teletherapy CBT for anxiety and depression in people with diabetes
This trial tests a unified, talk-therapy program delivered by video (telemedicine) to help with anxiety and depressive symptoms. If you have type 1 diabetes and symptoms of anxiety or depression, it may help you learn coping skills and improve mood.
Boston, MassachusettsAges 18–64
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,419 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.