Clinical trials
Depression, Anxiety clinical trials
Below are recruiting depression, anxiety clinical trials, each written for real people, not researchers. We’re tracking 441 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06988410Recruiting
Income changes and mental health study
This study looks at how ups and downs in income affect mental health. If you're a woman between 18 and 60 living with up to 4 other adults, you may be able to join.
TamaleAges 18–60 - NCT06994988Recruiting
Smart band-aid study for chronic pain in women
This trial tests a special band-aid that measures chronic pain. Women with chronic pain or healthy women may join to help researchers learn how this device works.
Chicago, IllinoisAges 18 years+ - NCT06985784Recruiting
Virtual reality for head and neck cancer patients and caregivers
This study tests whether using virtual reality can help reduce depression, anxiety, and pain in people with head and neck cancer and their caregivers. You and your caregiver may be able to use VR headsets together as part of your treatment.
Duarte, CaliforniaAges 18 years+ - NCT06979089Recruiting
Stress relief program for Dutch SMEs
This trial tests an online stress-management program for employees in small to medium-sized businesses in the Netherlands. It aims to help people with high stress levels feel better and cope more effectively.
Amsterdam, North HollandAges 18 years+ - NCT06981598Recruiting
Preventing mental health issues with unit-based support
This trial studies how having behavioral health technicians (mental health support people) work directly in military units can help prevent psychological problems. It is for service members who are currently seeing one of these technicians, or for the technicians themselves who are embedded in a unit.
New York, New YorkAges 18 years+ - NCT06978166Recruiting
Digital therapy for chronic pain and mood
This study tests a smartphone app that gives you personalized tips and exercises to help manage chronic pain along with depression or anxiety. It is designed for adults ages 45 and older and aims to see if these digital check-ins can improve how you feel day to day.
St Louis, MissouriAges 45 years+ - NCT06604481Recruiting
Online coaching for family caregivers
This study tests a 6-week online coaching program to help family caregivers reduce stress and build resilience. You'll learn practical strategies you can use at home.
Hong KongAges 18 years+ - NCT06929208Recruiting
Music and heart rate during procedures
This trial studies how listening to music affects your heart rate and stress response during a procedure like surgery or a pain treatment. It may help you relax and feel more comfortable.
SingaporeAges 21–90 - NCT06455397Recruiting
Building emotional awareness and mental health for parents
This trial tests a program called BEAM that helps parents and caregivers of young children (ages 2–5) manage stress, depression, anxiety, or anger. You'll get support from a peer coach through check-ins and learn skills to feel better.
Winnipeg, ManitobaAges 18 years+ - NCT06423417Recruiting
LifeHack program for student mental wellbeing
This trial tests a program called LifeHack to see if it helps university students feel better mentally. You'll take part in an online program and answer questions about your wellbeing.
AmsterdamAges 16–99 - NCT06901739Recruiting
Synbiotic for mental health in obesity
This trial tests if a synbiotic (a mix of probiotics and prebiotics) can improve mental health in people with obesity. It may help if you have obesity and also struggle with anxiety or depression.
Valencia, ValenciaAges 18–65 - NCT06899165RecruitingPhase 2
Psilocybin therapy for inherited trauma
This trial tests whether psilocybin (a psychedelic substance) combined with therapy can help adult children of genocide survivors who experience symptoms of trauma, depression, or anxiety. The goal is to see if this approach can reduce the emotional impact of intergenerational trauma.
New York, New YorkAges 18 years+ - NCT06874790Recruiting
Web-based mental health app study for Latina women
This study tests a web-based app to help Latina women in Los Angeles or Orange County who are feeling anxious or depressed. If you are not currently in therapy or on medication, you may be able to join from home using your smartphone or computer.
Los Angeles, CaliforniaAges 18 years+ - NCT06839859RecruitingPhase 2
Family Acceptance Project online pilot study
This trial tests an online program called Family Acceptance Project to help LGBTQ+ youth of color and their families improve acceptance and reduce rejection. You and a caregiver will join separate online group sessions to learn communication and support skills.
Ann Arbor, MichiganAges 14 years+ - NCT06722781Recruiting
Online group therapy for common mental health conditions
This trial tests an online group therapy for people waiting for high intensity CBT. It aims to provide quicker support for conditions like depression, anxiety, and PTSD.
Doncaster, South YorkshireAges 17 years+ - NCT06827951Recruiting
Parent-child therapy for young kids with behavior issues
This study tests if a therapy called Parent-Child Interaction Therapy (PCIT) helps parents of young children with behavioral concerns. You and your child would attend sessions together to improve your relationship and manage behaviors.
Gainesville, FloridaAges 18–89 - NCT06812247Recruiting
Therapy dog visits for hospitalized trauma patients
This study looks at whether visits from therapy dogs can help people who are in the hospital after a traumatic injury feel better. You must be able to talk to the research team and not be afraid of dogs.
Boston, MassachusettsAges 18 years+ - NCT06806176Recruiting
Study of CAT-GSH for returning patients
This trial is checking if a version of CBT-GSH (Cognitive Behavioral Therapy Guided Self-Help) works well for people who've had it before and are coming back for help with anxiety or depression. You'd get the same kind of low-intensity support again.
Ashton-under-LyneAges 16 years+ - NCT06788977Recruiting
Migraine treatment in pregnancy with a nerve stimulation device
This trial tests if a device that gently stimulates a nerve on your forehead can safely treat migraines during pregnancy. You'll use the device at home and track your headaches via text or email.
Darien, ConnecticutAges 18–44 - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT05908565Recruiting
Digital therapy program for Latinx college students in East LA
This study tests a digital (online) prevention and therapy program called STAND to see if it improves engagement and outcomes. You may be able to participate if you’re a Latinx student at East Los Angeles College and can complete online assessments.
Los Angeles, CaliforniaAges 18–40 - NCT06745349Recruiting
Online sleep course for adults in Saskatchewan
This study tests an online sleep course for adults who have trouble falling or staying asleep. It aims to help improve sleep without requiring in-person visits.
Regina, SaskatchewanAges 18 years+ - NCT06266611RecruitingPhase 2
Cannabis for cancer symptom relief
This trial tests whether cannabis can help cancer patients manage symptoms like sleep trouble, pain, and mood changes. It's for people who are new to using cannabis for these issues.
Aurora, ColoradoAges 25 years+ - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80
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Common questions
- Are there clinical trials for depression, anxiety?
- Yes. Clin2 currently lists 441 recruiting depression, anxiety studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression, anxiety trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression, anxiety trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.